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Morghan C Lucas
Morghan C Lucas
MGZ - Medical Genetics Centre
在 mgz-muenchen.de 的电子邮件经过验证 - 首页
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Accurate detection of m6A RNA modifications in native RNA sequences
H Liu, O Begik, MC Lucas, JM Ramirez, CE Mason, D Wiener, S Schwartz, ...
Nature communications 10 (1), 4079, 2019
3822019
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ...
Science translational medicine 9 (384), eaai8504, 2017
2412017
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ...
Nature communications 10 (1), 3637, 2019
2072019
Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing
O Begik, MC Lucas, LP Pryszcz, JM Ramirez, R Medina, I Milenkovic, ...
Nature biotechnology 39 (10), 1278-1291, 2021
1792021
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
J Chang, MC Lucas, LE Leonte, M Garcia-Montolio, LB Singh, AD Findlay, ...
Oncotarget 8 (16), 26066, 2017
1192017
Recent advances in understanding the complexities of metastasis
JL Chitty, EC Filipe, MC Lucas, D Herrmann, TR Cox, P Timpson
F1000Research 7, 2018
942018
Recent advances in understanding the complexities of metastasis
JL Chitty, EC Filipe, MC Lucas, D Herrmann, TR Cox, P Timpson
F1000Research 7, 2018
942018
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ...
Cell reports 21 (1), 274-288, 2017
942017
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
M Samuel, P Fonseka, R Sanwlani, L Gangoda, SH Chee, ...
Nature Communications 12 (1), 3950, 2021
932021
SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer
NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ...
Oncogene 36 (30), 4288-4298, 2017
882017
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis
M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ...
Nature communications 13 (1), 4587, 2022
832022
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib
AIJ Young, AMK Law, L Castillo, S Chong, HD Cullen, M Koehler, ...
Breast Cancer Research 18, 1-15, 2016
812016
Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue
Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ...
Cell reports 14 (1), 152-167, 2016
682016
Integrative analyses of the RNA modification machinery reveal tissue-and cancer-specific signatures
O Begik, MC Lucas, H Liu, JM Ramirez, JS Mattick, EM Novoa
Genome biology 21, 1-24, 2020
652020
Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing
MC Lucas, LP Pryszcz, R Medina, I Milenkovic, N Camacho, V Marchand, ...
Nature Biotechnology 42 (1), 72-86, 2024
562024
Molecular barcoding of native RNAs using nanopore sequencing and deep learning
MA Smith, T Ersavas, JM Ferguson, H Liu, MC Lucas, O Begik, L Bojarski, ...
Genome research 30 (9), 1345-1353, 2020
522020
Molecular mobility and activity in an intravital imaging setting–implications for cancer progression and targeting
M Nobis, SC Warren, MC Lucas, KJ Murphy, D Herrmann, P Timpson
Journal of Cell Science 131 (5), jcs206995, 2018
352018
Long-read sequencing in the era of epigenomics and epitranscriptomics
MC Lucas, EM Novoa
Nature Methods 20 (1), 25-29, 2023
302023
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
KJ Murphy, DA Reed, C Vennin, JRW Conway, M Nobis, JX Yin, ...
Science advances 7 (40), eabh0363, 2021
272021
‘MCC’protein interacts with E-cadherin and β-catenin strengthening cell–cell adhesion of HCT116 colon cancer cells
FA Benthani, D Herrmann, PN Tran, L Pangon, MC Lucas, AH Allam, ...
Oncogene 37 (5), 663-672, 2018
252018
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