SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology FP Veras, MC Pontelli, CM Silva, JE Toller-Kawahisa, M de Lima, ... Journal of Experimental Medicine 217 (12), e20201129, 2020 | 868 | 2020 |
The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ... Nature medicine 23 (5), 631-637, 2017 | 385 | 2017 |
Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial MI Lopes, LP Bonjorno, MC Giannini, NB Amaral, PI Menezes, SM Dib, ... RMD open 7 (1), e001455, 2021 | 230 | 2021 |
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ... Nature medicine 24 (3), 292-303, 2018 | 168 | 2018 |
12-Lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, ... Cell metabolism 30 (4), 768-783. e7, 2019 | 157 | 2019 |
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice MC Calixto, L Lintomen, DM André, LO Leiria, D Ferreira, C Lellis-Santos, ... PloS one 8 (10), e76786, 2013 | 130 | 2013 |
Obesity and asthma: beyond TH2 inflammation LOS Leiria, MA Martins, MJA Saad Metabolism 64 (2), 172-181, 2015 | 129 | 2015 |
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 103 | 2020 |
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis F Shamsi, R Xue, TL Huang, M Lundh, Y Liu, LO Leiria, MD Lynes, ... Nature communications 11 (1), 1421, 2020 | 80 | 2020 |
Cold-activated lipid dynamics in adipose tissue highlights a role for cardiolipin in thermogenic metabolism MD Lynes, F Shamsi, EG Sustarsic, LO Leiria, CH Wang, SC Su, ... Cell reports 24 (3), 781-790, 2018 | 76 | 2018 |
Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin‐induced diabetic mice: evidence of a role for L‐type voltage‐operated Ca2+ … LOS Leiria, FZT Monica, F Carvalho, MA Claudino, CF Franco‐Penteado, ... British journal of pharmacology 163 (6), 1276-1288, 2011 | 70 | 2011 |
Lipidomics of brown and white adipose tissue: Implications for energy metabolism LO Leiria, YH Tseng Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 61 | 2020 |
Therapy with resveratrol attenuates obesity-associated allergic airway inflammation in mice DM Andre, MC Calixto, C Sollon, EC Alexandre, LO Leiria, N Tobar, ... International immunopharmacology 38, 298-305, 2016 | 54 | 2016 |
The soluble guanylyl cyclase activator BAY 60-2770 ameliorates overactive bladder in obese mice LO Leiria, FH Silva, APC Davel, EC Alexandre, MC Calixto, G De Nucci, ... The Journal of urology 191 (2), 539-547, 2014 | 53 | 2014 |
Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation S Sugimoto, HA Mena, BE Sansbury, S Kobayashi, T Tsuji, CH Wang, ... Nature metabolism 4 (6), 775-790, 2022 | 51 | 2022 |
Insulin relaxes bladder via PI3K/AKT/eNOS pathway activation in mucosa: unfolded protein response‐dependent insulin resistance as a cause of obesity‐associated overactive bladder LO Leiria, C Sollon, FR Báu, FZ Mónica, CL D’Ancona, G De Nucci, ... The Journal of physiology 591 (9), 2259-2273, 2013 | 49 | 2013 |
Soluble guanylyl cyclase (sGC) degradation and impairment of nitric oxide-mediated responses in urethra from obese mice: Reversal by the sGC activator BAY 60-2770 EC Alexandre, LO Leiria, FH Silva, CB Mendes-Silvério, FB Calmasini, ... Journal of Pharmacology and Experimental Therapeutics 349 (1), 2-9, 2014 | 47 | 2014 |
Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology CMS Silva, CWS Wanderley, FP Veras, AV Gonçalves, MHF Lima, ... Critical Care 26 (1), 206, 2022 | 45 | 2022 |
Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes M Sato, T Tsuji, K Yang, X Ren, JM Dreyfuss, TL Huang, CH Wang, ... PLoS biology 18 (2), e3000630, 2020 | 45 | 2020 |
Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway CB Mendes-Silverio, LOS Leiria, RP Morganti, GF Anhe, S Marcondes, ... PLoS One 7 (11), e47223, 2012 | 44 | 2012 |