Structural biology and regulation of protein import into the nucleus M Christie, CW Chang, G Róna, KM Smith, AG Stewart, AAS Takeda, ... Journal of molecular biology 428 (10), 2060-2090, 2016 | 265 | 2016 |
The C-terminal 18 amino acid region of dengue virus NS5 regulates its subcellular localization and contains a conserved arginine residue essential for infectious virus production MYF Tay, K Smith, IHW Ng, KWK Chan, Y Zhao, EE Ooi, J Lescar, D Luo, ... PLoS pathogens 12 (9), e1005886, 2016 | 84 | 2016 |
Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses KM Smith, S Tsimbalyuk, MR Edwards, EM Cross, J Batra, ... Nature communications 9 (1), 3703, 2018 | 55 | 2018 |
Nuclear import inhibitor N-(4-hydroxyphenyl) retinamide targets Zika virus (ZIKV) nonstructural protein 5 to inhibit ZIKV infection C Wang, SNY Yang, K Smith, JK Forwood, DA Jans Biochemical and biophysical research communications 493 (4), 1555-1559, 2017 | 50 | 2017 |
Targeting nuclear LSD1 to reprogram cancer cells and reinvigorate exhausted T cells via a novel LSD1-EOMES switch WJ Tu, RD McCuaig, AHY Tan, K Hardy, N Seddiki, S Ali, JE Dahlstrom, ... Frontiers in Immunology 11, 1228, 2020 | 43 | 2020 |
Zika Virus NS5 forms supramolecular nuclear bodies that sequester importin-α and modulate the host immune and pro-inflammatory response in neuronal cells IHW Ng, KWK Chan, MJA Tan, CP Gwee, KM Smith, SJ Jeffress, WG Saw, ... ACS infectious diseases 5 (6), 932-948, 2019 | 42 | 2019 |
Structural basis for importin-α binding of the human immunodeficiency virus tat KM Smith, Z Himiari, S Tsimbalyuk, JK Forwood Scientific reports 7 (1), 1650, 2017 | 30 | 2017 |
Lysozyme conformational changes with ionic liquids: Spectroscopic, small angle x-ray scattering and crystallographic study Q Han, KM Smith, C Darmanin, TM Ryan, CJ Drummond, TL Greaves Journal of Colloid and Interface Science 585, 433-443, 2021 | 29 | 2021 |
Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting KM Smith, V Di Antonio, L Bellucci, DR Thomas, F Caporuscio, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (8), 1114-1129, 2018 | 28 | 2018 |
MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity TS Munasinghe, MR Edwards, S Tsimbalyuk, OA Vogel, KM Smith, ... Nature Communications 13 (1), 1604, 2022 | 16 | 2022 |
Repeat spillover of beak and feather disease virus into an endangered parrot highlights the risk associated with endemic pathogen loss in endangered species S Das, K Smith, S Sarker, A Peters, K Adriaanse, P Eden, SA Ghorashi, ... Journal of wildlife diseases 56 (4), 896-906, 2020 | 14 | 2020 |
Fast fragment-and compound-screening pipeline at the Swiss Light Source JW Kaminski, L Vera, DP Stegmann, J Vering, D Eris, KML Smith, ... Biological Crystallography 78 (3), 328-336, 2022 | 12 | 2022 |
Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids Q Han, Y Su, KM Smith, J Binns, CJ Drummond, C Darmanin, TL Greaves Journal of Colloid and Interface Science 650, 1393-1405, 2023 | 11 | 2023 |
Assessing circovirus gene flow in multiple spill-over events S Das, K Smith, S Sarker, A Peters, K Adriaanse, P Eden, SA Ghorashi, ... Virus genes 55 (6), 802-814, 2019 | 10 | 2019 |
Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase YB Khandokar, P Srivastava, N Cowieson, S Sarker, D Aragao, S Das, ... Journal of Biological Chemistry 292 (50), 20461-20471, 2017 | 10 | 2017 |
Probing ligand binding of endothiapepsin bytemperature-resolved'macromolecular crystallography CY Huang, S Aumonier, S Engilberge, D Eris, KML Smith, F Leonarski, ... Acta Crystallographica Section D: Structural Biology 78 (8), 964-974, 2022 | 9 | 2022 |
Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii EM Cross, D Aragão, KM Smith, KI Shaw, JD Nanson, SR Raidal, ... Biochemical and biophysical research communications 518 (3), 465-471, 2019 | 8 | 2019 |
SDU–software for high-throughput automated data collection at the Swiss Light Source KML Smith, E Panepucci, JW Kaminski, S Aumonier, CY Huang, D Eris, ... Synchrotron Radiation 30 (3), 538-545, 2023 | 4 | 2023 |
CX-ASAP: a high-throughput tool for the serial refinement and analysis of crystallographic data collected under varying conditions AJ Thompson, KML Smith, JK Clegg, JR Price Journal of Applied Crystallography 56 (2), 558-564, 2023 | 2 | 2023 |
Thermosalience Revealed on the Atomic Scale: Rapid Synchrotron Techniques Uncover Molecular Motion Preceding Crystal Jumping A Angeloski, JR Price, C Ennis, K Smith, AM McDonagh, A Dowd, ... Crystal Growth & Design 22 (3), 1951-1959, 2022 | 1 | 2022 |