A family of evolution–entropy hybrid methods for ranking protein residues by importance I Mihalek, I Reš, O Lichtarge Journal of molecular biology 336 (5), 1265-1282, 2004 | 338 | 2004 |
An accurate, sensitive, and scalable method to identify functional sites in protein structures H Yao, DM Kristensen, I Mihalek, ME Sowa, C Shaw, M Kimmel, L Kavraki, ... Journal of molecular biology 326 (1), 255-261, 2003 | 245 | 2003 |
WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification GS Coombs, J Yu, CA Canning, CA Veltri, TM Covey, JK Cheong, ... Journal of cell science 123 (19), 3357-3367, 2010 | 213 | 2010 |
An evolution based classifier for prediction of protein interfaces without using protein structures I Reš, I Mihalek, O Lichtarge Bioinformatics 21 (10), 2496-2501, 2005 | 131 | 2005 |
Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions A Ribes-Zamora, I Mihalek, O Lichtarge, AA Bertuch Nature structural & molecular biology 14 (4), 301-307, 2007 | 127 | 2007 |
TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres A Ribes-Zamora, SM Indiviglio, I Mihalek, CL Williams, AA Bertuch Cell reports 5 (1), 194-206, 2013 | 99 | 2013 |
Evolutionary trace report_maker: a new type of service for comparative analysis of proteins I Mihalek, I Reš, O Lichtarge Bioinformatics 22 (13), 1656-1657, 2006 | 73 | 2006 |
Spectrum of neurodevelopmental disease associated with the GNAO1 guanosine triphosphate–binding region MK Kelly, M Park, I Mihalek, A Rochtus, M Gramm, E Pérez‐Palma, ... Epilepsia 60 (3), 406-418, 2019 | 64 | 2019 |
Defining the Phenotype in Congenital Disorder of Glycosylation Due to ALG1 Mutations E Morava, J Vodopiutz, DJ Lefeber, AR Janecke, WM Schmidt, S Lechner, ... Pediatrics 130 (4), e1034-e1039, 2012 | 54 | 2012 |
Accurate and scalable identification of functional sites by evolutionary tracing O Lichtarge, H Yao, DM Kristensen, S Madabushi, I Mihalek Journal of Structural and Functional Genomics 4, 159-166, 2003 | 54 | 2003 |
Mutations in RIT1 cause Noonan syndrome – additional functional evidence and expanding the clinical phenotype M Koenighofer, CY Hung, JL McCauley, J Dallman, EJ Back, I Mihalek, ... Clinical genetics 89 (3), 359-366, 2016 | 53 | 2016 |
Combining inference from evolution and geometric probability in protein structure evaluation I Mihalek, I Reš, H Yao, O Lichtarge Journal of molecular biology 331 (1), 263-279, 2003 | 49 | 2003 |
Cancer-associated mutations in the ribosomal protein L5 gene dysregulate the HDM2/p53-mediated ribosome biogenesis checkpoint I Oršolić, S Bursać, D Jurada, I Drmić Hofman, Z Dembić, J Bartek, ... Oncogene 39 (17), 3443-3457, 2020 | 40 | 2020 |
Active site coupling in PDE: PKA complexes promotes resetting of mammalian cAMP signaling S Krishnamurthy, BS Moorthy, LX Xiang, LX Shan, K Bharatham, ... Biophysical journal 107 (6), 1426-1440, 2014 | 38 | 2014 |
Helix straightening as an activation mechanism in the gelsolin superfamily of actin regulatory proteins H Wang, S Chumnarnsilpa, A Loonchanta, Q Li, YM Kuan, S Robine, ... Journal of Biological Chemistry 284 (32), 21265-21269, 2009 | 31 | 2009 |
The C-terminal extension unique to the long isoform of the shelterin component TIN2 enhances its interaction with TRF2 in a phosphorylation-and dyskeratosis congenita cluster … ND Nelson, LM Dodson, L Escudero, AT Sukumar, CL Williams, I Mihalek, ... Molecular and cellular biology 38 (12), e00025-18, 2018 | 28 | 2018 |
Manifestation of hawkinsinuria in a patient compound heterozygous for hawkinsinuria and tyrosinemia III I Mihalek, O Lichtarge, A Jalan, J Vodopiutz, A Muhl, OA Bodamer Molecular genetics and metabolism 91 (4), 379-383, 2007 | 24 | 2007 |
A structure and evolution-guided Monte Carlo sequence selection strategy for multiple alignment-based analysis of proteins I Mihalek, I Reš, O Lichtarge Bioinformatics 22 (2), 149-156, 2006 | 23 | 2006 |
deconSTRUCT: general purpose protein database search on the substructure level ZH Zhang, K Bharatham, WA Sherman, I Mihalek Nucleic acids research 38 (suppl_2), W590-W594, 2010 | 22 | 2010 |
On itinerant water molecules and detectability of protein–protein interfaces through comparative analysis of homologues I Mihalek, I Reš, O Lichtarge Journal of molecular biology 369 (2), 584-595, 2007 | 22 | 2007 |