Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation M Wichert, N Krall, W Decurtins, RM Franzini, F Pretto, P Schneider, ... Nature chemistry 7 (3), 241-249, 2015 | 213 | 2015 |
20 years of DNA-encoded chemical libraries L Mannocci, M Leimbacher, M Wichert, J Scheuermann, D Neri Chemical Communications 47 (48), 12747-12753, 2011 | 178 | 2011 |
Automated screening for small organic ligands using DNA-encoded chemical libraries W Decurtins, M Wichert, RM Franzini, F Buller, MA Stravs, Y Zhang, D Neri, ... Nature protocols 11 (4), 764-780, 2016 | 132 | 2016 |
Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library RM Franzini, T Ekblad, N Zhong, M Wichert, W Decurtins, A Nauer, ... Angewandte Chemie 127 (13), 3999-4003, 2015 | 106 | 2015 |
Targeting carbonic anhydrase IX with small organic ligands M Wichert, N Krall Current opinion in chemical biology 26, 48-54, 2015 | 37 | 2015 |
A multifaceted hit-finding approach reveals novel LC3 family ligands M Steffek, E Helgason, N Popovych, L Rougé, JM Bruning, KS Li, ... Biochemistry 62 (3), 633-644, 2022 | 14 | 2022 |
Augmenting Chemical Space with DNA-encoded Library Technology and Machine Learning: Medicinal Chemistry and Chemical Biology Highlights L Guasch, M Reutlinger, D Stoffler, M Wichert Chimia 75 (1-2), 105-105, 2021 | 7 | 2021 |
Small molecule drug conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert ES Patent App. 15,702,001 T, 2019 | 3 | 2019 |
Production of encoded chemical libraries W Decurtins, R Franzini, D Neri, J Scheuermann, M Wichert US Patent 10,240,147, 2019 | 2 | 2019 |
Small molecule drug conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert US Patent 10,016,511, 2018 | 1 | 2018 |
Challenges and Prospects of DNA-Encoded Library Data Interpretation M Wichert, L Guasch, RM Franzini Chemical Reviews 124 (22), 12551-12572, 2024 | | 2024 |
Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding J Liang, MJ Lambrecht, TL Arenzana, S Aubert-Nicol, L Bao, F Broccatelli, ... ACS Medicinal Chemistry Letters, 2024 | | 2024 |
Small molecule drug conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert US Patent App. 18/170,914, 2023 | | 2023 |
Small Molecule Drug Conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert US Patent App. 17/209,519, 2021 | | 2021 |
Production of encoded chemical libraries W Decurtins, R Franzini, D Neri, J Scheuermann, M Wichert US Patent App. 16/365,437, 2020 | | 2020 |
Small Molecule Drug Conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert US Patent App. 16/004,921, 2018 | | 2018 |
Small molecule drug conjugates N Krall, W Decurtins, D Neri, J Scheuermann, M Wichert US Patent 9,884,122, 2018 | | 2018 |
Bile Acids, Chemical Libraries, Ebola Virus, and Bacterial Uracil M Wichert Chemistry & Biology 22, 2015 | | 2015 |
DNA-encoded self-assembling chemical library technology for de novo ligand discovery and tumor targeting applications MA Wichert ETH Zurich, 2015 | | 2015 |
DNA-encoded chemical libraries: An emerging technology for efficient ligand discovery M Leimbacher, L Mannocci, M Wichert, J Scheuermann, D Neri MEDCHEM NEWS 22 (2), 7-14, 2012 | | 2012 |