Direct conversion of human fibroblasts to dopaminergic neurons U Pfisterer, A Kirkeby, O Torper, J Wood, J Nelander, A Dufour, ... Proceedings of the National Academy of Sciences 108 (25), 10343-10348, 2011 | 917 | 2011 |
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions A Kirkeby, S Grealish, DA Wolf, J Nelander, J Wood, M Lundblad, ... Cell reports 1 (6), 703-714, 2012 | 772 | 2012 |
Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment YM Ganat, EL Calder, S Kriks, J Nelander, EY Tu, F Jia, D Battista, ... The Journal of clinical investigation 122 (8), 2928-2939, 2012 | 176 | 2012 |
TRIM28 controls a gene regulatory network based on endogenous retroviruses in human neural progenitor cells PL Brattås, ME Jönsson, L Fasching, JN Wahlestedt, M Shahsavani, ... Cell reports 18 (1), 1-11, 2017 | 104 | 2017 |
hESC-derived dopaminergic transplants integrate into basal ganglia circuitry in a preclinical model of Parkinson’s disease AF Adler, T Cardoso, S Nolbrant, B Mattsson, DB Hoban, U Jarl, ... Cell reports 28 (13), 3462-3473. e5, 2019 | 86 | 2019 |
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol A Kirkeby, J Nelander, M Parmar Frontiers in cellular neuroscience 6, 64, 2013 | 66 | 2013 |
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of Parkinsonian rats T Cardoso, AF Adler, B Mattsson, DB Hoban, S Nolbrant, JN Wahlestedt, ... Journal of Comparative Neurology 526 (13), 2133-2146, 2018 | 62 | 2018 |
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD DB Hoban, S Shrigley, B Mattsson, LS Breger, U Jarl, T Cardoso, ... Proceedings of the National Academy of Sciences 117 (26), 15209-15220, 2020 | 60 | 2020 |
Organization of the human embryonic ventral mesencephalon J Nelander, JB Hebsgaard, M Parmar Gene Expression Patterns 9 (8), 555-561, 2009 | 54 | 2009 |
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors R Sachdeva, ME Jönsson, J Nelander, A Kirkeby, C Guibentif, B Gentner, ... Proceedings of the National Academy of Sciences 107 (25), 11602-11607, 2010 | 50 | 2010 |
Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics JB Hebsgaard, J Nelander, H Sabelström, ME Jönsson, S Stott, M Parmar Glia 57 (15), 1648-1659, 2009 | 47 | 2009 |
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor ME Jönsson, J Nelander Wahlestedt, M Åkerblom, A Kirkeby, J Malmevik, ... Development 142 (18), 3166-3177, 2015 | 45 | 2015 |
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PD A Kirkeby, J Nelander, DB Hoban, N Rogelius, H Bjartmarz, P Storm, ... Cell Stem Cell 30 (10), 1299-1314. e9, 2023 | 37 | 2023 |
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain M Birtele, P Storm, Y Sharma, J Kajtez, JN Wahlestedt, E Sozzi, F Nilsson, ... Development 149 (23), dev200504, 2022 | 16 | 2022 |
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases J Nelander, S Grealish, M Parmar Neuroreport 24 (18), 1025-1030, 2013 | 12 | 2013 |
Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons A Fiorenzano, M Birtele, JN Wahlestedt, M Parmar Heliyon 7 (1), 2021 | 7 | 2021 |
Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures M Birtele, Y Sharma, P Storm, J Kajtez, JN Wahlestedt, E Sozzi, F Nilsson, ... BioRxiv, 2020.10. 01.322495, 2020 | 3 | 2020 |
Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells P Rifes, M Isaksson, C Rusimbi, A Ramón Santonja, J Nelander, T Laurell, ... Stem Cell Research & Therapy 14 (1), 354, 2023 | 1 | 2023 |
APCDD1 outperforms other dopaminergic cell surface markers in benchmarking study A Kirkeby, A Schörling, E Hänninen, P Rifes, A Salvador, A Holm, ... | | 2023 |
Longitudinal in vivo PET imaging of human ESC-derived dopamine neurons in minipig TP Lillethorup, DB Hoban, B Mattsson, D Orlowski, JN Wahlestedt, ... JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 41 (1_ SUPPL), 154-154, 2021 | | 2021 |