Systematic discovery of in vivo phosphorylation networks R Linding, LJ Jensen, GJ Ostheimer, MATM van Vugt, C Jørgensen, ... Cell 129 (7), 1415-1426, 2007 | 881 | 2007 |
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells MATM Van Vugt, A Brás, RH Medema Molecular cell 15 (5), 799-811, 2004 | 458 | 2004 |
Gene expression analysis identifies global gene dosage sensitivity in cancer RSN Fehrmann, JM Karjalainen, M Krajewska, HJ Westra, D Maloney, ... Nature genetics 47 (2), 115-125, 2015 | 396 | 2015 |
Relevance of tumor-infiltrating immune cell composition and functionality for disease outcome in breast cancer RD Bense, C Sotiriou, MJ Piccart-Gebhart, JBAG Haanen, ... Journal of the National Cancer Institute 109 (1), djw192, 2017 | 365 | 2017 |
Rectal and colon cancer: Not just a different anatomic site K Tamas, AME Walenkamp, EGE De Vries, M Van Vugt, RG Beets-Tan, ... Cancer treatment reviews 41 (8), 671-679, 2015 | 345 | 2015 |
Getting in and out of mitosis with Polo-like kinase-1 MATM van Vugt, RH Medema Oncogene 24 (17), 2844-2859, 2005 | 341 | 2005 |
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint MATM van Vugt, AK Gardino, R Linding, GJ Ostheimer, HC Reinhardt, ... PLoS biology 8 (1), e1000287, 2010 | 290 | 2010 |
14-3-3σ controls mitotic translation to facilitate cytokinesis EW Wilker, MATM Van Vugt, SC Artim, PH Huang, CP Petersen, ... Nature 446 (7133), 329-332, 2007 | 286 | 2007 |
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization HC Reinhardt, P Hasskamp, I Schmedding, S Morandell, MATM van Vugt, ... Molecular cell 40 (1), 34-49, 2010 | 271 | 2010 |
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery I Mamely, MATM van Vugt, VAJ Smits, JI Semple, B Lemmens, A Perrakis, ... Current Biology 16 (19), 1950-1955, 2006 | 271 | 2006 |
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ... Cancer cell 33 (6), 1078-1093. e12, 2018 | 265 | 2018 |
Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis MATM Van Vugt, BCM Van De Weerdt, G Vader, H Janssen, J Calafat, ... Journal of Biological Chemistry 279 (35), 36841-36854, 2004 | 237 | 2004 |
Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM-or ATR-dependent fashion MATM van Vugt, VAJ Smits, R Klompmaker, RH Medema Journal of Biological Chemistry 276 (45), 41656-41660, 2001 | 225 | 2001 |
cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers C Hong, M Schubert, AE Tijhuis, M Requesens, M Roorda, ... Nature 607 (7918), 366-373, 2022 | 161 | 2022 |
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling T van Harn, F Foijer, M van Vugt, R Banerjee, F Yang, A Oostra, H Joenje, ... Genes & development 24 (13), 1377-1388, 2010 | 147 | 2010 |
Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination M Krajewska, AM Heijink, Y Bisselink, RI Seinstra, HHW Sillje, ... Oncogene 32 (24), 3001-3008, 2013 | 137 | 2013 |
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity AM Heijink, F Talens, LT Jae, SE van Gijn, RSN Fehrmann, ... Nature communications 10 (1), 100, 2019 | 118 | 2019 |
The DNA damage response during mitosis AM Heijink, M Krajewska, MATM van Vugt Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 750 (1 …, 2013 | 118 | 2013 |
ATR inhibition preferentially targets homologous recombination-deficient tumor cells M Krajewska, RSN Fehrmann, PM Schoonen, S Labib, EGE De Vries, ... Oncogene 34 (26), 3474-3481, 2015 | 113 | 2015 |
Functional dynamics of Polo-like kinase 1 at the centrosome K Kishi, MATM Van Vugt, K Okamoto, Y Hayashi, MB Yaffe Molecular and cellular biology 29 (11), 3134-3150, 2009 | 113 | 2009 |