| Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells N Ioannou, AG Dalgleish, AM Seddon, D Mackintosh, U Guertler, F Solca, ... British journal of cancer 105 (10), 1554-1562, 2011 | 91 | 2011 |
| Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity BS Hanna, L Llao-Cid, M Iskar, PM Roessner, LC Klett, JKL Wong, Y Paul, ... Immunity 54 (12), 2825-2841. e10, 2021 | 73 | 2021 |
| Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy N Ioannou, PR Hagner, M Stokes, AK Gandhi, B Apollonio, M Fanous, ... Blood, The Journal of the American Society of Hematology 137 (2), 216-231, 2021 | 56 | 2021 |
| Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells N Ioannou, AM Seddon, A Dalgleish, D Mackintosh, H Modjtahedi BMC cancer 13, 1-12, 2013 | 55 | 2013 |
| Immunomodulatory drugs for the treatment of B cell malignancies N Ioannou, K Jain, AG Ramsay International journal of molecular sciences 22 (16), 8572, 2021 | 33 | 2021 |
| Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition N Ioannou, AM Seddon, A Dalgleish, D Mackintosh, F Solca, ... International journal of oncology 48 (3), 908-918, 2016 | 33 | 2016 |
| Expression pattern and targeting of HER family members and IGF-IR in pancreatic cancer N Ioannou, AM Seddon, A Dalgleish, D Mackintosh, H Modjtahedi Front Biosci (Landmark Ed) 17 (7), 2698-2724, 2012 | 26 | 2012 |
| Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses E Gargiulo, E Viry, PE Morande, A Largeot, S Gonder, F Xian, N Ioannou, ... Blood cancer discovery 4 (1), 54-77, 2023 | 23 | 2023 |
| T-cell dynamics in chronic lymphocytic leukemia under different treatment modalities A Vardi, E Vlachonikola, D Papazoglou, F Psomopoulos, K Kotta, ... Clinical Cancer Research 26 (18), 4958-4969, 2020 | 22 | 2020 |
| Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma CE Graham, A Jozwik, R Quartey-Papafio, N Ioannou, AM Metelo, ... Leukemia 35 (12), 3581-3584, 2021 | 20 | 2021 |
| A detailed analysis of parameters supporting the engraftment and growth of chronic lymphocytic leukemia cells in immune-deficient mice PEM Patten, G Ferrer, SS Chen, JE Kolitz, KR Rai, SL Allen, JC Barrientos, ... Frontiers in immunology 12, 627020, 2021 | 20 | 2021 |
| Understanding the immune-stroma microenvironment in B cell malignancies for effective immunotherapy B Apollonio, N Ioannou, D Papazoglou, AG Ramsay Frontiers in oncology 11, 626818, 2021 | 19 | 2021 |
| Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures AM Vaca, N Ioannou, M Sivina, E Vlachonikola, K Clise-Dwyer, E Kim, ... Leukemia 36 (5), 1324-1335, 2022 | 14 | 2022 |
| Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of … T Khan, AM Seddon, AG Dalgleish, S Khelwatty, N Ioannou, S Mudan, ... Oncology Reports 44 (6), 2581-2594, 2020 | 14 | 2020 |
| miR-181c-BRK1 axis plays a key role in actin cytoskeleton-dependent T cell function SP Lim, N Ioannou, AG Ramsay, D Darling, J Gäken, GJ Mufti Journal of leukocyte biology 103 (5), 855-866, 2018 | 9 | 2018 |
| Ibrutinib-based therapy reinvigorates CD8+ T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial D Papazoglou, XV Wang, TD Shanafelt, CE Lesnick, N Ioannou, ... Blood 143 (1), 57-63, 2024 | 8 | 2024 |
| The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy F Arruga, M Rubin, D Papazoglou, A Iannello, N Ioannou, R Moia, ... Haematologica 108 (8), 2101, 2023 | 8 | 2023 |
| Interleukin-27 potentiates CD8+ T-cell-mediated anti-tumor immunity in chronic lymphocytic leukemia G Pagano, IF Botana, M Wierz, PM Roessner, N Ioannou, X Zhou, ... Haematologica, 2023 | 8 | 2023 |
| Longitudinal evaluation of T-cells in clinical monoclonal B-cell lymphocytosis (MBL) SA Parikh, AG Ramsay, J Boysen, C Lesnick, W Ding, K Medina, ... Haematologica 101, 223-223, 2016 | 6 | 2016 |
| Allogeneic anti-CD19 CAR T cells manufactured from healthy donors provide a unique cellular product with distinct phenotypic characteristics compared to CAR T cells generated … C Graham, A Jozwik, R Quartey-Papafio, N Ioannou, AM Metelo, C Scala, ... Blood 134, 3228, 2019 | 5 | 2019 |
