mTORC1 regulates mitochondrial integrated stress response and mitochondrial myopathy progression NA Khan, J Nikkanen, S Yatsuga, C Jackson, L Wang, S Pradhan, ... Cell metabolism 26 (2), 419-428. e5, 2017 | 345 | 2017 |
CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular Endothelial Growth Factor-C … M Jeltsch, SK Jha, D Tvorogov, A Anisimov, VM Leppänen, T Holopainen, ... Circulation 129 (19), 1962-1971, 2014 | 259 | 2014 |
VEGFB/VEGFR1-induced expansion of adipose vasculature counteracts obesity and related metabolic complications MR Robciuc, R Kivelä, IM Williams, JF de Boer, TH van Dijk, H Elamaa, ... Cell metabolism 23 (4), 712-724, 2016 | 226 | 2016 |
The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis HI Chen, B Sharma, BN Akerberg, HJ Numi, R Kivelä, P Saharinen, ... Development 141 (23), 4500-4512, 2014 | 210 | 2014 |
Vascular endothelial growth factor-B in physiology and disease M Bry, R Kivelä, VM Leppänen, K Alitalo Physiological reviews 94 (3), 779-794, 2014 | 195 | 2014 |
VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart R Kivelä, M Bry, MR Robciuc, M Räsänen, M Taavitsainen, JMU Silvola, ... EMBO molecular medicine 6 (3), 307-321, 2014 | 176 | 2014 |
Cardiomyocyte—endothelial cell interactions in cardiac remodeling and regeneration V Talman, R Kivelä Frontiers in cardiovascular medicine 5, 101, 2018 | 165 | 2018 |
Effects of experimental type 1 diabetes and exercise training on angiogenic gene expression and capillarization in skeletal muscle R Kivelä, M Silvennoinen, AM Touvra, T Maarit Lehti, H Kainulainen, ... The FASEB journal 20 (9), 1570-1572, 2006 | 165 | 2006 |
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation M Bry, R Kivelä, T Holopainen, A Anisimov, T Tammela, J Soronen, ... Circulation 122 (17), 1725-1733, 2010 | 156 | 2010 |
Endothelial cells regulate physiological cardiomyocyte growth via VEGFR2-mediated paracrine signaling R Kivelä, KA Hemanthakumar, K Vaparanta, M Robciuc, Y Izumiya, ... Circulation 139 (22), 2570-2584, 2019 | 135 | 2019 |
Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice R Kivelä, M Silvennoinen, M Lehti, S Jalava, V Vihko, H Kainulainen Cardiovascular diabetology 7, 1-10, 2008 | 122 | 2008 |
VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection M Räsänen, J Degerman, TA Nissinen, I Miinalainen, R Kerkelä, ... Proceedings of the National Academy of Sciences 113 (46), 13144-13149, 2016 | 121 | 2016 |
Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy JJ Hulmi, M Silvennoinen, M Lehti, R Kivelä, H Kainulainen American Journal of Physiology-Endocrinology and Metabolism 302 (3), E307-E315, 2012 | 103 | 2012 |
Interrelationships between muscle structure, muscle strength, and running economy H KYRÖLÄINEN, R KIVELÄ, S Koskinen, J McBride, JL Andersen, ... Medicine & Science in Sports & Exercise 35 (1), 45-49, 2003 | 91 | 2003 |
Lymphatic and immune cell cross-talk regulates cardiac recovery after experimental myocardial infarction M Houssari, A Dumesnil, V Tardif, R Kivelä, N Pizzinat, I Boukhalfa, ... Arteriosclerosis, thrombosis, and vascular biology 40 (7), 1722-1737, 2020 | 79 | 2020 |
Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk R Kivelä, M Silvennoinen, M Lehti, R Rinnankoski-Tuikka, T Purhonen, ... The FASEB journal 24 (11), 4565, 2010 | 78 | 2010 |
Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes TA Nissinen, J Degerman, M Räsänen, AR Poikonen, S Koskinen, ... Scientific reports 6 (1), 32695, 2016 | 76 | 2016 |
VEGF-B promotes endocardium-derived coronary vessel development and cardiac regeneration M Räsänen, I Sultan, J Paech, KA Hemanthakumar, W Yu, L He, J Tang, ... Circulation 143 (1), 65-77, 2021 | 74 | 2021 |
The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation R Kivelä, I Salmela, YH Nguyen, TV Petrova, HA Koistinen, Z Wiener, ... Nature communications 7 (1), 13124, 2016 | 67 | 2016 |
Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses TA Nissinen, J Hentilä, F Penna, A Lampinen, JH Lautaoja, V Fachada, ... Journal of cachexia, sarcopenia and muscle 9 (3), 514-529, 2018 | 66 | 2018 |