Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases N Shah, AS Mohammad, P Saralkar, SA Sprowls, SD Vickers, D John, ... Pharmacological research 132, 47-68, 2018 | 125 | 2018 |
Improving CNS delivery to brain metastases by blood–tumor barrier disruption SA Sprowls, TA Arsiwala, JR Bumgarner, N Shah, SS Lateef, ... Trends in cancer 5 (8), 495-505, 2019 | 90 | 2019 |
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 60 | 2023 |
Development of a Cx46 targeting strategy for cancer stem cells EE Mulkearns-Hubert, LA Torre-Healy, DJ Silver, JT Eurich, D Bayik, ... Cell reports 27 (4), 1062-1072. e5, 2019 | 40 | 2019 |
Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery TA Arsiwala, SA Sprowls, KE Blethen, CE Adkins, PA Saralkar, ... Neoplasia 23 (7), 676-691, 2021 | 37 | 2021 |
Y Chromosome LncRNA Are Involved in Radiation Response of Male Non–Small Cell Lung Cancer Cells T Brownmiller, JA Juric, AD Ivey, BM Harvey, ES Westemeier, MT Winters, ... Cancer research 80 (19), 4046-4057, 2020 | 30 | 2020 |
MiR-34a interacts with cytochrome c and shapes stroke outcomes H Hu, EA Hone, EAP Provencher, SA Sprowls, I Farooqi, DR Corbin, ... Scientific reports 10 (1), 3233, 2020 | 25 | 2020 |
Biphasic blood-brain barrier openings after stroke EA Hone, H Hu, SA Sprowls, I Farooqi, K Grasmick, PR Lockman, ... Neurol Disord Stroke Int 1 (2), 1011, 2018 | 22 | 2018 |
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma K Mitchell, SA Sprowls, S Arora, S Shakya, DJ Silver, CM Goins, ... Genes & Development 37 (3-4), 86-102, 2023 | 21 | 2023 |
Hypomethylating agent azacitidine is effective in treating brain metastasis triple-negative breast cancer through regulation of DNA methylation of keratin 18 gene C Butler, S Sprowls, G Szalai, T Arsiwala, P Saralkar, B Straight, ... Translational Oncology 13 (6), 100775, 2020 | 21 | 2020 |
Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases KE Blethen, TA Arsiwala, RA Fladeland, SA Sprowls, DM Panchal, ... Neuro-Oncology Advances 3 (Supplement_5), v133-v143, 2021 | 16 | 2021 |
Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis N Shah, Z Liu, RM Tallman, A Mohammad, SA Sprowls, PA Saralkar, ... BMC cancer 20, 1-13, 2020 | 14 | 2020 |
Effects of whole-brain radiation therapy on the blood–brain barrier in immunocompetent and immunocompromised mouse models KE Blethen, SA Sprowls, TA Arsiwala, CP Wolford, DM Panchal, ... Radiation Oncology 18 (1), 22, 2023 | 11 | 2023 |
Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model TA Arsiwala, SA Sprowls, KE Blethen, RA Fladeland, CP Wolford, ... Fluids and Barriers of the CNS 19 (1), 72, 2022 | 10 | 2022 |
Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo Z Liu, N Shah, KL Marshall, SA Sprowls, P Saralkar, A Mohammad, ... Archives of toxicology 95 (11), 3575-3587, 2021 | 7 | 2021 |
Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy TA Arsiwala, KE Blethen, CP Wolford, DM Panchal, SA Sprowls, ... Frontiers in Oncology 13, 1104594, 2023 | 6 | 2023 |
Circadian influences on chemotherapy efficacy in a mouse model of brain metastases of breast cancer WH Walker, SA Sprowls, JR Bumgarner, JA Liu, OH Meléndez-Fernández, ... Frontiers in Oncology 11, 752331, 2021 | 6 | 2021 |
Chemotherapeutic activity of pitavastatin in vincristine resistant B-cell acute lymphoblastic leukemia D Piktel, JC Moore, S Nesbit, SA Sprowls, MD Craig, SL Rellick, RR Nair, ... Cancers 15 (3), 707, 2023 | 4 | 2023 |
Irradiator commissioning and dosimetry for assessment of LQ α and β parameters, radiation dosing schema, and in vivo dose deposition SA Sprowls, VJ Pizzuti, W Pentz, DC Nwafor, RAC Siochi, PR Lockman JoVE (Journal of Visualized Experiments), e61692, 2021 | 4 | 2021 |
Breaking down the barrier to medulloblastoma treatment: Piezo2 knockout disrupts the BTB and increases vascular permeability SA Sprowls, JD Lathia Neuron 111 (1), 3-5, 2023 | 3 | 2023 |