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Lekh Dahal
Lekh Dahal
在 liverpool.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo
A Roghanian, I Teige, L Mårtensson, KL Cox, M Kovacek, A Ljungars, ...
Cancer cell 27 (4), 473-488, 2015
1492015
Antibodies to costimulatory receptor 4-1BB enhance anti-tumor immunity via T regulatory cell depletion and promotion of CD8 T cell effector function
SL Buchan, L Dou, M Remer, SG Booth, SN Dunn, C Lai, M Semmrich, ...
Immunity 49 (5), 958-970. e7, 2018
1372018
The soluble isoform of CTLA‐4 as a regulator of T‐cell responses
FJ Ward, LN Dahal, SK Wijesekera, SK Abdul‐Jawad, T Kaewarpai, H Xu, ...
European journal of immunology 43 (5), 1274-1285, 2013
1332013
Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies
X Yu, HTC Chan, CM Orr, O Dadas, SG Booth, LN Dahal, CA Penfold, ...
Cancer cell 33 (4), 664-675. e4, 2018
982018
Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies
TRW Tipton, A Roghanian, RJ Oldham, MJ Carter, KL Cox, CI Mockridge, ...
Blood, The Journal of the American Society of Hematology 125 (12), 1901-1909, 2015
892015
STING activation reverses lymphoma-mediated resistance to antibody immunotherapy
LN Dahal, L Dou, K Hussain, R Liu, A Earley, KL Cox, S Murinello, I Tracy, ...
Cancer research 77 (13), 3619-3631, 2017
762017
Antibody tumor targeting is enhanced by CD27 agonists through myeloid recruitment
AH Turaj, K Hussain, KL Cox, MJJ Rose-Zerilli, J Testa, LN Dahal, ...
Cancer cell 32 (6), 777-791. e6, 2017
712017
FcγR requirements leading to successful immunotherapy
LN Dahal, A Roghanian, SA Beers, MS Cragg
Immunological reviews 268 (1), 104-122, 2015
562015
Improved multiplex immunohistochemistry for immune microenvironment evaluation of mouse formalin-fixed, paraffin-embedded tissues
N Sorrelle, D Ganguly, ATA Dominguez, Y Zhang, H Huang, LN Dahal, ...
The Journal of Immunology 202 (1), 292-299, 2019
512019
Development and characterization of monoclonal antibodies specific for mouse and human Fcγ receptors
AL Tutt, S James, SA Laversin, TRW Tipton, M Ashton-Key, RR French, ...
The Journal of Immunology 195 (11), 5503-5516, 2015
512015
Optimising B-cell depletion in autoimmune disease: is obinutuzumab the answer?
V Reddy, LN Dahal, MS Cragg, M Leandro
Drug discovery today 21 (8), 1330-1338, 2016
492016
New revelations from an old receptor: Immunoregulatory functions of the inhibitory Fc gamma receptor, FcγRIIB (CD32B)
A Roghanian, RJ Stopforth, LN Dahal, MS Cragg
Journal of leukocyte biology 103 (6), 1077-1088, 2018
362018
Targeting the alternatively spliced soluble isoform of CTLA-4: prospects for immunotherapy?
FJ Ward, LN Dahal, RC Khanolkar, SP Shankar, RN Barker
Immunotherapy 6 (10), 1073-1084, 2014
302014
Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus
LN Dahal, N Basu, H Youssef, RC Khanolkar, RN Barker, LP Erwig, ...
Arthritis research & therapy 18, 1-11, 2016
292016
Shaving is an epiphenomenon of type I and II anti-CD20–mediated phagocytosis, whereas antigenic modulation limits type I monoclonal antibody efficacy
LN Dahal, CY Huang, RJ Stopforth, A Mead, K Chan, JX Bowater, ...
The Journal of Immunology 201 (4), 1211-1221, 2018
222018
Investigating the role of indoleamine 2, 3-dioxygenase in acute myeloid leukemia: a systematic review
G Wells, PT Kennedy, LN Dahal
Frontiers in immunology 12, 651687, 2021
202021
Antibodies specifically directed to the soluble form of ctla-4
FJ Ward, RN Barker, LN Dahal
202017
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
J Bloehdorn, A Braun, A Taylor-Weiner, BMC Jebaraj, S Robrecht, ...
Nature Communications 12 (1), 5395, 2021
192021
On the road to immunotherapy—prospects for treating head and neck cancers with checkpoint inhibitor antibodies
FJ Ward, LN Dahal, R Abu-Eid
Frontiers in immunology 9, 2182, 2018
182018
PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis
MJ Carter, KL Cox, SJ Blakemore, AH Turaj, RJ Oldham, LN Dahal, ...
Leukemia 31 (6), 1423-1433, 2017
182017
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