An LXR-cholesterol axis creates a metabolic co-dependency for brain cancers GR Villa, JJ Hulce, C Zanca, J Bi, S Ikegami, GL Cahill, Y Gu, KM Lum, ... Cancer cell 30 (5), 683-693, 2016 | 285 | 2016 |
Altered cellular metabolism in gliomas—An emerging landscape of actionable co-dependency targets J Bi, S Chowdhry, S Wu, W Zhang, K Masui, PS Mischel Nature Reviews Cancer 20 (1), 57-70, 2020 | 242 | 2020 |
NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling S Chowdhry, C Zanca, U Rajkumar, T Koga, Y Diao, R Raviram, F Liu, ... Nature 569 (7757), 570-575, 2019 | 187 | 2019 |
mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT Y Gu, CP Albuquerque, D Braas, W Zhang, GR Villa, J Bi, S Ikegami, ... Molecular cell 67 (1), 128-138. e7, 2017 | 174 | 2017 |
Seipin promotes adipose tissue fat storage through the ER Ca2+-ATPase SERCA J Bi, W Wang, Z Liu, X Huang, Q Jiang, G Liu, Y Wang, X Huang Cell metabolism 19 (5), 861-871, 2014 | 161 | 2014 |
Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization J Bi, Y Xiang, H Chen, Z Liu, S Grönke, RP Kühnlein, X Huang Journal of cell science 125 (15), 3568-3577, 2012 | 161 | 2012 |
Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling J Bi, TA Ichu, C Zanca, H Yang, W Zhang, Y Gu, S Chowdhry, A Reed, ... Cell metabolism 30 (3), 525-538. e8, 2019 | 160 | 2019 |
Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation Y Tian, J Bi, G Shui, Z Liu, Y Xiang, Y Liu, MR Wenk, H Yang, X Huang PLoS genetics 7 (4), e1001364, 2011 | 150 | 2011 |
Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery, CD-19-0061, 2019 | 142 | 2019 |
Biogeography and hotspots of amphibian species of China: implications to reserve selection and conservation Y Chen, J Bi Current Science, 480-489, 2007 | 86 | 2007 |
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug J Bi, A Khan, J Tang, AM Armando, S Wu, W Zhang, RC Gimple, A Reed, ... Cell reports 37 (5), 2021 | 57 | 2021 |
Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance SH Wu, JF Bi, T Cloughesy, WK Cavenee, PS Mischel Cancer biology & medicine 11 (4), 255, 2014 | 55 | 2014 |
Targeting cancer's metabolic co-dependencies: A landscape shaped by genotype and tissue context J Bi, S Wu, W Zhang, PS Mischel Biochimica Et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 76-87, 2018 | 35 | 2018 |
TRIM-9 functions in the UNC-6/UNC-40 pathway to regulate ventral guidance S Song, Q Ge, J Wang, H Chen, S Tang, J Bi, X Li, Q Xie, X Huang Journal of Genetics and Genomics 38 (1), 1-11, 2011 | 27 | 2011 |
Acyl-CoA-Binding protein fuels gliomagenesis J Bi, PS Mischel Cell Metabolism 30 (2), 229-230, 2019 | 14 | 2019 |
A cell type selective YM155 prodrug targets receptor-interacting protein kinase 2 to induce brain cancer cell death TJ West, J Bi, F Martínez-Peña, EJ Curtis, NR Gazaniga, PS Mischel, ... Journal of the American Chemical Society 145 (15), 8355-8363, 2023 | 5 | 2023 |
bAP1 And PtEn stAbiLiZE iP3r3 to ProMotE cA2+-MEdiAtEd APoPtosis Y Gu, CP Albuquerque, D Braas, W Zhang, GR Villa, J Bi | | |