Genetic dissection of the α-globin super-enhancer in vivo D Hay, JR Hughes, C Babbs, JOJ Davies, BJ Graham, LLP Hanssen, ... Nature genetics 48 (8), 895-903, 2016 | 390 | 2016 |
Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ... Nature cell biology 19 (8), 952-961, 2017 | 224 | 2017 |
The relationship between genome structure and function AM Oudelaar, DR Higgs Nature Reviews Genetics 22 (3), 154-168, 2021 | 213 | 2021 |
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains AM Oudelaar, JOJ Davies, LLP Hanssen, JM Telenius, R Schwessinger, ... Nature genetics 50 (12), 1744-1751, 2018 | 186 | 2018 |
How best to identify chromosomal interactions: a comparison of approaches JOJ Davies, AM Oudelaar, DR Higgs, JR Hughes Nature methods 14 (2), 125-134, 2017 | 162 | 2017 |
DeepC: predicting 3D genome folding using megabase-scale transfer learning R Schwessinger, M Gosden, D Downes, RC Brown, AM Oudelaar, ... Nature Methods 17 (11), 1118-1124, 2020 | 145 | 2020 |
Defining genome architecture at base-pair resolution P Hua, M Badat, LLP Hanssen, LD Hentges, N Crump, DJ Downes, ... Nature 595 (7865), 125-129, 2021 | 131 | 2021 |
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation L Godfrey, NT Crump, R Thorne, IJ Lau, E Repapi, D Dimou, AL Smith, ... Nature communications 10 (1), 2803, 2019 | 128 | 2019 |
Dynamics of the 4D genome during in vivo lineage specification and differentiation AM Oudelaar, RA Beagrie, M Gosden, S de Ornellas, E Georgiades, ... Nature Communications 11 (1), 1-12, 2020 | 99 | 2020 |
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions JM Brown, NA Roberts, B Graham, D Waithe, C Lagerholm, JM Telenius, ... Nature communications 9 (1), 3849, 2018 | 76 | 2018 |
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus AM Oudelaar, CL Harrold, LLP Hanssen, JM Telenius, DR Higgs, ... Nature communications 10 (1), 1-8, 2019 | 73 | 2019 |
Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF A Aljahani, P Hua, MA Karpinska, K Quililan, JOJ Davies, AM Oudelaar Nature communications 13 (1), 2139, 2022 | 69 | 2022 |
Enhancers predominantly regulate gene expression during differentiation via transcription initiation MSC Larke, R Schwessinger, T Nojima, J Telenius, RA Beagrie, ... Molecular Cell, 2021 | 45 | 2021 |
The Mediator complex regulates enhancer-promoter interactions S Ramasamy, A Aljahani, MA Karpinska, TBN Cao, T Velychko, JN Cruz, ... Nature Structural & Molecular Biology 30 (7), 991-1000, 2023 | 38 | 2023 |
A Dynamic Folded Hairpin Conformation Is Associated with α-Globin Activation in Erythroid Cells AM Chiariello, S Bianco, AM Oudelaar, A Esposito, C Annunziatella, ... Cell Reports 30 (7), 2125-2135. e5, 2020 | 38 | 2020 |
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale DJ Downes, RA Beagrie, ME Gosden, J Telenius, SJ Carpenter, ... Nature Communications 12 (1), 1-15, 2021 | 37 | 2021 |
Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C AM Oudelaar, JOJ Davies, DJ Downes, DR Higgs, JR Hughes Nucleic acids research 45 (22), e184-e184, 2017 | 31 | 2017 |
Reactivation of a developmentally silenced embryonic globin gene AJ King, D Songdej, DJ Downes, RA Beagrie, S Liu, M Buckley, P Hua, ... Nature Communications 12 (1), 1-15, 2021 | 29 | 2021 |
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture DJ Downes, AL Smith, MA Karpinska, T Velychko, K Rue-Albrecht, D Sims, ... Nature Protocols 17 (2), 445-475, 2022 | 28 | 2022 |
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization AM Oudelaar, RA Beagrie, MT Kassouf, DR Higgs Current Opinion in Genetics & Development 67, 18-24, 2021 | 26 | 2021 |