Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy SN Byrareddy, J Arthos, C Cicala, F Villinger, KT Ortiz, D Little, N Sidell, ... Science 354 (6309), 197-202, 2016 | 252 | 2016 |
Computing in mammalian cells with nucleic acid strand exchange B Groves, YJ Chen, C Zurla, S Pochekailov, JL Kirschman, PJ Santangelo, ... Nature nanotechnology 11 (3), 287-294, 2016 | 212 | 2016 |
Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS AW Lifland, J Jung, E Alonas, C Zurla, JE Crowe Jr, PJ Santangelo Journal of virology 86 (15), 8245-8258, 2012 | 197 | 2012 |
Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques PJ Santangelo, KA Rogers, C Zurla, EL Blanchard, S Gumber, K Strait, ... Nature methods 12 (5), 427-432, 2015 | 176 | 2015 |
Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents EL Blanchard, D Vanover, SS Bawage, PM Tiwari, L Rotolo, J Beyersdorf, ... Nature biotechnology 39 (6), 717-726, 2021 | 159 | 2021 |
Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging KE Lindsay, SM Bhosle, C Zurla, J Beyersdorf, KA Rogers, D Vanover, ... Nature biomedical engineering 3 (5), 371-380, 2019 | 154 | 2019 |
Tethered particle motion as a diagnostic of DNA tether length PC Nelson, C Zurla, D Brogioli, JF Beausang, L Finzi, D Dunlap The Journal of Physical Chemistry B 110 (34), 17260-17267, 2006 | 144 | 2006 |
Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection PM Tiwari, D Vanover, KE Lindsay, SS Bawage, JL Kirschman, S Bhosle, ... Nature communications 9 (1), 3999, 2018 | 116 | 2018 |
Mild innate immune activation overrides efficient nanoparticle‐mediated RNA delivery MP Lokugamage, Z Gan, C Zurla, J Levin, FZ Islam, S Kalathoor, M Sato, ... Advanced materials 32 (1), 1904905, 2020 | 94 | 2020 |
Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA–protein correlations at the level of single cells JL Kirschman, S Bhosle, D Vanover, EL Blanchard, KH Loomis, C Zurla, ... Nucleic acids research 45 (12), e113-e113, 2017 | 73 | 2017 |
Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung L Rotolo, D Vanover, NC Bruno, HE Peck, C Zurla, J Murray, RK Noel, ... Nature materials 22 (3), 369-379, 2023 | 62 | 2023 |
DNA looping kinetics analyzed using diffusive hidden Markov model JF Beausang, C Zurla, C Manzo, D Dunlap, L Finzi, PC Nelson Biophysical journal 92 (8), L64-L66, 2007 | 61 | 2007 |
Multilevel autoregulation of λ repressor protein CI by DNA looping in vitro D Lewis, P Le, C Zurla, L Finzi, S Adhya Proceedings of the National Academy of Sciences 108 (36), 14807-14812, 2011 | 58 | 2011 |
Quantifying RNA–protein interactions in situ using modified-MTRIPs and proximity ligation J Jung, AW Lifland, C Zurla, EJ Alonas, PJ Santangelo Nucleic acids research 41 (1), e12-e12, 2013 | 56 | 2013 |
Characterizing mRNA interactions with RNA granules during translation initiation inhibition C Zurla, AW Lifland, PJ Santangelo PLoS One 6 (5), e19727, 2011 | 50 | 2011 |
Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection PJ Santangelo, C Cicala, SN Byrareddy, KT Ortiz, D Little, KE Lindsay, ... Mucosal immunology 11 (3), 932-946, 2018 | 46 | 2018 |
Novel tethered particle motion analysis of CI protein-mediated DNA looping in the regulation of bacteriophage lambda C Zurla, A Franzini, G Galli, DD Dunlap, DEA Lewis, S Adhya, L Finzi Journal of Physics: Condensed Matter 18 (14), S225, 2006 | 45 | 2006 |
Enhanced tethered-particle motion analysis reveals viscous effects S Kumar, C Manzo, C Zurla, S Ucuncuoglu, L Finzi, D Dunlap Biophysical journal 106 (2), 399-409, 2014 | 44 | 2014 |
Elementary simulation of tethered Brownian motion JF Beausang, C Zurla, L Finzi, L Sullivan, PC Nelson American Journal of Physics 75 (6), 520-523, 2007 | 43 | 2007 |
Aerosol delivery of synthetic mRNA to vaginal mucosa leads to durable expression of broadly neutralizing antibodies against HIV KE Lindsay, D Vanover, M Thoresen, H King, P Xiao, P Badial, M Araínga, ... Molecular Therapy 28 (3), 805-819, 2020 | 41 | 2020 |