Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2 V Monteil, H Kwon, P Prado, A Hagelkrüys, RA Wimmer, M Stahl, ... Cell 181 (4), 905-913. e7, 2020 | 2262 | 2020 |
Antigen presentation in the thymus for positive selection and central tolerance induction L Klein, M Hinterberger, G Wirnsberger, B Kyewski Nature Reviews Immunology 9 (12), 833-844, 2009 | 807 | 2009 |
A dual role for autophagy in a murine model of lung cancer S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ... Nature communications 5 (1), 3056, 2014 | 439 | 2014 |
Seventy-five genetic loci influencing the human red blood cell P Van Der Harst, W Zhang, I Mateo Leach, A Rendon, N Verweij, J Sehmi, ... Nature 492 (7429), 369-375, 2012 | 390 | 2012 |
Signaling mechanisms, interaction partners, and target genes of STAT6 D Hebenstreit, G Wirnsberger, J Horejs-Hoeck, A Duschl Cytokine & growth factor reviews 17 (3), 173-188, 2006 | 356 | 2006 |
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ... Cell stem cell 9 (6), 563-574, 2011 | 276 | 2011 |
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ... Nature 563 (7732), 564-568, 2018 | 208 | 2018 |
RANKL/RANK control Brca1 mutation-driven mammary tumors V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ... Cell research 26 (7), 761-774, 2016 | 163 | 2016 |
Regulatory T‐cell differentiation versus clonal deletion of autoreactive thymocytes G Wirnsberger, M Hinterberger, L Klein Immunology and cell biology 89 (1), 45-53, 2011 | 128 | 2011 |
Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control G Wirnsberger, F Mair, L Klein Proceedings of the National Academy of Sciences 106 (25), 10278-10283, 2009 | 120 | 2009 |
Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection V Monteil, M Dyczynski, VM Lauschke, H Kwon, G Wirnsberger, ... EMBO molecular medicine 13 (1), e13426, 2021 | 113 | 2021 |
IL‐4 induces expression of TARC/CCL17 via two STAT6 binding sites G Wirnsberger, D Hebenstreit, G Posselt, J Horejs‐Hoeck, A Duschl European journal of immunology 36 (7), 1882-1891, 2006 | 105 | 2006 |
Inhibition of CBLB protects from lethal Candida albicans sepsis G Wirnsberger, F Zwolanek, T Asaoka, I Kozieradzki, L Tortola, ... Nature medicine 22 (8), 915-923, 2016 | 99 | 2016 |
Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice K Lahl, CT Mayer, T Bopp, J Huehn, C Loddenkemper, G Eberl, ... The Journal of Immunology 183 (9), 5662-5672, 2009 | 74 | 2009 |
The tumor suppressor Hace1 is a critical regulator of TNFR1-mediated cell fate L Tortola, R Nitsch, MJM Bertrand, M Kogler, Y Redouane, I Kozieradzki, ... Cell reports 15 (7), 1481-1492, 2016 | 68 | 2016 |
Identification of lectin receptors for conserved SARS‐CoV‐2 glycosylation sites D Hoffmann, S Mereiter, Y Jin Oh, V Monteil, E Elder, R Zhu, D Canena, ... The EMBO Journal 40 (19), e108375, 2021 | 62 | 2021 |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense G Wirnsberger, F Zwolanek, J Stadlmann, L Tortola, SW Liu, T Perlot, ... Nature genetics 46 (9), 1028-1033, 2014 | 60 | 2014 |
B7/CD28 in central tolerance: costimulation promotes maturation of regulatory T cell precursors and prevents their clonal deletion M Hinterberger, G Wirnsberger, L Klein Frontiers in immunology 2, 30, 2011 | 49 | 2011 |
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF-and IFNγ-driven immunopathology R Gawish, P Starkl, L Pimenov, A Hladik, K Lakovits, F Oberndorfer, ... Elife 11, e74623, 2022 | 47 | 2022 |
Clinical grade ACE2 as a universal agent to block SARS‐CoV‐2 variants V Monteil, B Eaton, E Postnikova, M Murphy, B Braunsfeld, I Crozier, ... EMBO Molecular Medicine 14 (8), e15230, 2022 | 36 | 2022 |