| Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity … A Kaidi, D Qualtrough, AC Williams, C Paraskeva Cancer research 66 (13), 6683-6691, 2006 | 396 | 2006 |
| Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment D Qualtrough, A Buda, W Gaffield, AC Williams, C Paraskeva International journal of cancer 110 (6), 831-837, 2004 | 259 | 2004 |
| Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence SD Chell, IR Witherden, RR Dobson, M Moorghen, AA Herman, ... Cancer research 66 (6), 3106-3113, 2006 | 161 | 2006 |
| Butyrate downregulates α2β1 integrin: a possible role in the induction of apoptosis in colorectal cancer cell lines A Buda, D Qualtrough, MA Jepson, D Martines, C Paraskeva, M Pignatelli Gut 52 (5), 729-734, 2003 | 80 | 2003 |
| Prostaglandin F2α stimulates motility and invasion in colorectal tumor cells D Qualtrough, A Kaidi, S Chell, HN Jabbour, AC Williams, C Paraskeva International journal of cancer 121 (4), 734-740, 2007 | 74 | 2007 |
| Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system D Qualtrough, T Hinoi, E Fearon, C Paraskeva Gut 51 (2), 184-190, 2002 | 70 | 2002 |
| Inhibition of COX‐2 with NS‐398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy N Banu, A Buda, S Chell, D Elder, M Moorghen, C Paraskeva, ... Cell proliferation 40 (5), 768-779, 2007 | 55 | 2007 |
| Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines LC Playle, DJ Hicks, D Qualtrough, C Paraskeva British journal of cancer 87 (3), 352-358, 2002 | 49 | 2002 |
| The potential role of hedgehog signaling in the luminal/basal phenotype of breast epithelia and in breast cancer invasion and metastasis A Flemban, D Qualtrough Cancers 7 (3), 1863-1884, 2015 | 43 | 2015 |
| The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro D Qualtrough, K Singh, N Banu, C Paraskeva, M Pignatelli British journal of cancer 101 (7), 1124-1129, 2009 | 40 | 2009 |
| The hedgehog inhibitor cyclopamine reduces β-catenin-Tcf transcriptional activity, induces E-cadherin expression, and reduces invasion in colorectal cancer cells D Qualtrough, P Rees, B Speight, AC Williams, C Paraskeva Cancers 7 (3), 1885-1899, 2015 | 34 | 2015 |
| Prospects in NSAID-derived chemoprevention of colorectal cancer S Chell, HA Patsos, D Qualtrough, AM H-zadeh, DJ Hicks, A Kaidi, ... Biochemical Society Transactions 33 (4), 667-671, 2005 | 31 | 2005 |
| The actin-bundling protein fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair D Qualtrough, K Smallwood, D Littlejohns, M Pignatelli BMC gastroenterology 11 (1), 1-8, 2011 | 26 | 2011 |
| Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line CS Daly, A Flemban, M Shafei, ME Conway, D Qualtrough, SJ Dean Oncology reports 39 (2), 483-490, 2018 | 22 | 2018 |
| BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer MA Shafei, T Forshaw, J Davis, A Flemban, D Qualtrough, S Dean, ... Oncotarget 11 (21), 1971, 2020 | 15 | 2020 |
| Differential expression of the BCAT isoforms between breast cancer subtypes MA Shafei, A Flemban, C Daly, P Kendrick, P White, S Dean, ... Breast Cancer, 1-16, 2020 | 12 | 2020 |
| The effect of cyclopamine on hedgehog signalling pathway in breast cancer cells A Flemban, D Qualtrough BREAST CANCER RESEARCH AND TREATMENT 159 (1), 183-183, 2016 | | 2016 |
| 19-P018 Notch signalling in colonic epithelial cells: Potential roles in inflammatory bowel disease and tissue repair D Qualtrough, P Rees, M Pignatelli Mechanisms of Development, S296, 2009 | | 2009 |
| Fascin expression is increased in a size-dependent manner in colorectal adenomas and promotes cellular motility. D Qualtrough, K Singh, N Banu, M Pignatelli JOURNAL OF PATHOLOGY 207, 44-44, 2005 | | 2005 |
| Cyclooxygenase-2 inhibition decreases colon cancer cell motility through modulating epidermal growth factor receptor transactivation NA Banu, A Buda, S Chell, D Qualtrough, D Elder, M Moorghen, ... JOURNAL OF PATHOLOGY 204, 48A-48A, 2004 | | 2004 |
