Screening out irrelevant cell-based models of disease P Horvath, N Aulner, M Bickle, AM Davies, ED Nery, D Ebner, ... Nature reviews Drug discovery 15 (11), 751-769, 2016 | 523 | 2016 |
Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene RA Rollins, M Korom, N Aulner, A Martens, D Dorsett Molecular and cellular biology 24 (8), 3100-3111, 2004 | 287 | 2004 |
Sequence characteristics of functional siRNAs B Jagla, N Aulner, PD Kelly, DA Song, A Volchuk, A Zatorski, D Shum, ... Rna 11 (6), 864-872, 2005 | 196 | 2005 |
Intracellular bacteria encode inhibitory SNARE-like proteins F Paumet, J Wesolowski, A Garcia-Diaz, C Delevoye, N Aulner, ... PloS one 4 (10), e7375, 2009 | 111 | 2009 |
Shigella subverts the host recycling compartment to rupture its vacuole N Mellouk, A Weiner, N Aulner, C Schmitt, M Elbaum, SL Shorte, ... Cell host & microbe 16 (4), 517-530, 2014 | 108 | 2014 |
HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes C Nobile, D Rudnicka, M Hasan, N Aulner, F Porrot, C Machu, O Renaud, ... Journal of virology 84 (5), 2282-2293, 2010 | 103 | 2010 |
High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery N Aulner, A Danckaert, E Rouault-Hardoin, J Desrivot, O Helynck, ... PLoS neglected tropical diseases 7 (4), e2154, 2013 | 78 | 2013 |
The AT-Hook Protein D1 Is Essential for Drosophila melanogaster Development and Is Implicated in Position-Effect Variegation N Aulner, C Monod, G Mandicourt, D Jullien, O Cuvier, A Sall, S Janssen, ... Molecular and Cellular Biology 22 (4), 1218-1232, 2002 | 77 | 2002 |
Next-generation phenotypic screening in early drug discovery for infectious diseases N Aulner, A Danckaert, JE Ihm, D Shum, SL Shorte Trends in parasitology 35 (7), 559-570, 2019 | 74 | 2019 |
Targeting macrophage histone H3 modification as a leishmania strategy to dampen the NF-κB/NLRP3-mediated inflammatory response H Lecoeur, E Prina, T Rosazza, K Kokou, P N’Diaye, N Aulner, H Varet, ... Cell reports 30 (6), 1870-1882. e4, 2020 | 62 | 2020 |
The Drosophila poly (A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro B Benoit, M Simonelig, A Nemeth, N Aulner, U Kühn, E Wahle, ... Nucleic acids research 27 (19), 3771-3778, 1999 | 60 | 1999 |
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection N Rachidi, JF Taly, E Durieu, O Leclercq, N Aulner, E Prina, P Pescher, ... Antimicrobial agents and chemotherapy 58 (3), 1501-1515, 2014 | 57 | 2014 |
Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I N Beaujean, C Bouniol-Baly, C Monod, K Kissa, D Jullien, N Aulner, ... Developmental Biology 221 (2), 337-354, 2000 | 55 | 2000 |
From drug screening to target deconvolution: a target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with antileishmanial activity E Durieu, E Prina, O Leclercq, N Oumata, N Gaboriaud-Kolar, ... Antimicrobial agents and chemotherapy 60 (5), 2822-2833, 2016 | 53 | 2016 |
The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors S Ortica, N Tarantino, N Aulner, A Israël, N Gupta‐Rossi The FASEB Journal 28 (2), 603-614, 2014 | 47 | 2014 |
Identification of N-(quinolin-8-yl) benzenesulfonamides as agents capable of down-regulating NFκB activity within two separate high-throughput screens of NFκB activation Y Xie, SX Deng, CJ Thomas, Y Liu, YQ Zhang, A Rinderspacher, ... Bioorganic & medicinal chemistry letters 18 (1), 329-335, 2008 | 32 | 2008 |
Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening S Lamotte, N Aulner, GF Späth, E Prina Scientific reports 9 (1), 438, 2019 | 25 | 2019 |
LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images S Herbert, L Valon, L Mancini, N Dray, P Caldarelli, J Gros, E Esposito, ... BMC biology 19, 1-13, 2021 | 22 | 2021 |
Modification of position‐effect variegation by competition for binding to Drosophila satellites C Monod, N Aulner, O Cuvier, E Käs EMBO reports, 2002 | 19 | 2002 |
Potent inhibitors of Huntingtin protein aggregation in a cell-based assay A Rinderspacher, ML Cremona, Y Liu, SX Deng, Y Xie, G Gong, N Aulner, ... Bioorganic & medicinal chemistry letters 19 (6), 1715-1717, 2009 | 17 | 2009 |