Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial H Mehanna, M Robinson, A Hartley, A Kong, B Foran, T Fulton-Lieuw, ... The Lancet 393 (10166), 51-60, 2019 | 951 | 2019 |
Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection Z Wang, F Li, J Rufo, C Chen, S Yang, L Li, J Zhang, J Cheng, Y Kim, ... The Journal of Molecular Diagnostics 22 (1), 50-59, 2020 | 139 | 2020 |
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis H Mehanna, M Taberna, C Von Buchwald, S Tous, J Brooks, M Mena, ... The Lancet Oncology 24 (3), 239-251, 2023 | 96 | 2023 |
Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer JM Brooks, AN Menezes, M Ibrahim, L Archer, N Lal, CJ Bagnall, ... Clinical Cancer Research 25 (17), 5315-5328, 2019 | 92 | 2019 |
Human papillomavirus (HPV) vaccine effectiveness and potential herd immunity for reducing oncogenic oropharyngeal HPV-16 prevalence in the United Kingdom: a cross-sectional study H Mehanna, TS Bryant, J Babrah, K Louie, JL Bryant, RJ Spruce, N Batis, ... Clinical Infectious Diseases 69 (8), 1296-1302, 2019 | 49 | 2019 |
Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams) C Grønhøj, DH Jensen, C Dehlendorff, L Marklund, S Wagner, ... British Journal of Cancer 118 (12), 1672-1681, 2018 | 44 | 2018 |
A digital score of tumour‐associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma M Shaban, SEA Raza, M Hassan, A Jamshed, S Mushtaq, A Loya, N Batis, ... The Journal of Pathology 256 (2), 174-185, 2022 | 31 | 2022 |
Circulating tumour cell biomarkers in head and neck cancer: current progress and future prospects K Payne, J Brooks, R Spruce, N Batis, G Taylor, P Nankivell, H Mehanna Cancers 11 (8), 1115, 2019 | 31 | 2019 |
The clinical utility of cell-free DNA measurement in differentiated thyroid cancer: a systematic review JM Fussey, JL Bryant, N Batis, RJ Spruce, A Hartley, JS Good, ... Frontiers in oncology 8, 132, 2018 | 23 | 2018 |
5‐Chloroindole: a potent allosteric modulator of the 5‐HT3 receptor AS Newman, N Batis, G Grafton, F Caputo, CA Brady, JJ Lambert, ... British Journal of Pharmacology 169 (6), 1228-1238, 2013 | 23 | 2013 |
Lack of predictive tools for conventional and targeted cancer therapy: Barriers to biomarker development and clinical translation N Batis, JM Brooks, K Payne, N Sharma, P Nankivell, H Mehanna Advanced Drug Delivery Reviews 176, 113854, 2021 | 21 | 2021 |
Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma J Bryant, N Batis, AC Franke, G Clancey, M Hartley, G Ryan, J Brooks, ... Oncotarget 10 (50), 5229, 2019 | 18 | 2019 |
G-protein-coupled receptor (GPCR) signaling in the carotid body: roles in hypoxia and cardiovascular and respiratory disease HS Aldossary, AA Alzahrani, D Nathanael, EA Alhuthail, CJ Ray, N Batis, ... International Journal of Molecular Sciences 21 (17), 6012, 2020 | 17 | 2020 |
Mitochondrial succinate metabolism and reactive oxygen species are important but not essential for eliciting carotid body and ventilatory responses to hypoxia in the rat A Swiderska, AM Coney, AA Alzahrani, HS Aldossary, N Batis, CJ Ray, ... Antioxidants 10 (6), 840, 2021 | 16 | 2021 |
The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress HJ Gleneadie, AH Baker, N Batis, J Bryant, Y Jiang, SJH Clokie, ... Cancer letters 501, 172-186, 2021 | 12 | 2021 |
Surveillance of HPV-positive head and neck squamous cell carcinoma with circulating and salivary DNA biomarkers D Borsetto, J Cheng, K Payne, P Nankivell, N Batis, K Rao, S Bhide, F Li, ... Critical Reviews™ in Oncogenesis 23 (3-4), 2018 | 12 | 2018 |
Ultra-low DNA input into whole genome methylation assays and detection of oncogenic methylation and copy number variants in circulating tumour DNA C Whalley, K Payne, E Domingo, A Blake, S Richman, J Brooks, N Batis, ... Epigenomes 5 (1), 6, 2021 | 10 | 2021 |
Circulating tumour cell expression of immune markers as prognostic and therapeutic biomarkers in head and neck squamous cell carcinoma: a systematic review and meta-analysis K Payne, M Pugh, J Brooks, N Batis, G Taylor, P Nankivell, H Mehanna International Journal of Molecular Sciences 21 (21), 8229, 2020 | 10 | 2020 |
Immediate sample fixation increases circulating tumour cell (CTC) capture and preserves phenotype in head and neck squamous cell carcinoma: towards a standardised approach to … K Payne, JM Brooks, GS Taylor, N Batis, B Noyvert, Y Pan, P Nankivell, ... Cancers 13 (21), 5519, 2021 | 8 | 2021 |
Upper aerodigestive tract squamous cell carcinomas show distinct overall DNA methylation profiles and different molecular mechanisms behind WNT signaling disruption SC Soares-Lima, H Mehanna, D Camuzi, PT de Souza-Santos, TA Simao, ... Cancers 13 (12), 3014, 2021 | 8 | 2021 |