High-throughput screen for novel antimicrobials using a whole animal infection model TI Moy, AL Conery, J Larkins-Ford, G Wu, R Mazitschek, G Casadei, ... ACS chemical biology 4 (7), 527-533, 2009 | 255 | 2009 |
Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death NV Kirienko, DR Kirienko, J Larkins-Ford, C Wählby, G Ruvkun, ... Cell host & microbe 13 (4), 406-416, 2013 | 213 | 2013 |
OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development H Komatsu, MY Chao, J Larkins-Ford, ME Corkins, GA Somers, T Tucey, ... PLoS biology 6 (8), e196, 2008 | 169 | 2008 |
Sexual and social stimuli elicit rapid and contrasting genomic responses ME Cummings, J Larkins-Ford, CRL Reilly, RY Wong, M Ramsey, ... Proceedings of the Royal Society B: Biological Sciences 275 (1633), 393-402, 2008 | 151 | 2008 |
C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence K Singh, MY Chao, GA Somers, H Komatsu, ME Corkins, J Larkins-Ford, ... Current Biology 21 (10), 825-834, 2011 | 141 | 2011 |
Selective degradation of host RNA polymerase II transcripts by influenza A virus PA-X host shutoff protein DA Khaperskyy, S Schmaling, J Larkins-Ford, C McCormick, MM Gaglia PLoS pathogens 12 (2), e1005427, 2016 | 138 | 2016 |
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay I Okoli, JJ Coleman, E Tempakakis, WF An, E Holson, F Wagner, ... PloS one 4 (9), e7025, 2009 | 138 | 2009 |
Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis M Cokol, N Kuru, E Bicak, J Larkins-Ford, BB Aldridge Science advances 3 (10), e1701881, 2017 | 122 | 2017 |
Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus R Rajamuthiah, BB Fuchs, E Jayamani, Y Kim, J Larkins-Ford, A Conery, ... PloS one 9 (2), e89189, 2014 | 108 | 2014 |
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection R Pukkila-Worley, R Feinbaum, NV Kirienko, J Larkins-Ford, AL Conery, ... PLoS genetics 8 (6), e1002733, 2012 | 97 | 2012 |
High-and low-throughput scoring of fat mass and body fat distribution in C. elegans C Wählby, AL Conery, MA Bray, L Kamentsky, J Larkins-Ford, ... Methods 68 (3), 492-499, 2014 | 73 | 2014 |
Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model E Jayamani, R Rajamuthiah, J Larkins-Ford, BB Fuchs, AL Conery, ... Antimicrobial agents and chemotherapy 59 (3), 1728-1737, 2015 | 63 | 2015 |
High‐Throughput Screening for Novel Anti‐Infectives Using a C. elegans Pathogenesis Model AL Conery, J Larkins‐Ford, FM Ausubel, NV Kirienko Current protocols in chemical biology 6 (1), 25-37, 2014 | 58 | 2014 |
A new antibiotic with potent activity targets MscL I Iscla, R Wray, P Blount, J Larkins-Ford, AL Conery, FM Ausubel, S Ramu, ... The Journal of antibiotics 68 (7), 453-462, 2015 | 55 | 2015 |
lin-12 Notch functions in the adult nervous system of C. elegans MY Chao, J Larkins-Ford, TM Tucey, AC Hart BMC neuroscience 6, 1-12, 2005 | 43 | 2005 |
Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis J Larkins-Ford, T Greenstein, N Van, YN Degefu, MC Olson, A Sokolov, ... Cell systems 12 (11), 1046-1063. e7, 2021 | 39 | 2021 |
Transcriptomic signatures predict regulators of drug synergy and clinical regimen efficacy against tuberculosis S Ma, S Jaipalli, J Larkins-Ford, J Lohmiller, BB Aldridge, DR Sherman, ... MBio 10 (6), 10.1128/mbio. 02627-19, 2019 | 38 | 2019 |
Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components D Tomkiewicz, G Casadei, J Larkins-Ford, TI Moy, J Garner, JB Bremner, ... Antimicrobial agents and chemotherapy 54 (8), 3219-3224, 2010 | 36 | 2010 |
Morphological profiling of tubercle bacilli identifies drug pathways of action TC Smith, KM Pullen, MC Olson, ME McNellis, I Richardson, S Hu, ... Proceedings of the National Academy of Sciences 117 (31), 18744-18753, 2020 | 32 | 2020 |
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans JA Govindan, E Jayamani, X Zhang, P Breen, J Larkins-Ford, E Mylonakis, ... Nature cell biology 17 (10), 1294-1303, 2015 | 26 | 2015 |