| MDM2–p53 pathway in hepatocellular carcinoma X Meng, DA Franklin, J Dong, Y Zhang Cancer research 74 (24), 7161-7167, 2014 | 219 | 2014 |
| p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway DA Franklin, Y He, PL Leslie, AP Tikunov, N Fenger, JM Macdonald, ... Scientific reports 6 (1), 38067, 2016 | 86 | 2016 |
| The evolution of the ribosomal protein–MDM2–p53 pathway C Deisenroth, DA Franklin, Y Zhang Cold Spring Harbor perspectives in medicine 6 (12), a026138, 2016 | 67 | 2016 |
| Pyrimidine Nucleotides with 4-Alkyloxyimino and Terminal Tetraphosphate δ-Ester Modifications as Selective Agonists of the P2Y4 Receptor H Maruoka, MPS Jayasekara, MO Barrett, DA Franklin, S de Castro, ... Journal of medicinal chemistry 54 (12), 4018-4033, 2011 | 62 | 2011 |
| Protection against high-fat-diet-induced obesity in MDM2C305F mice due to reduced p53 activity and enhanced energy expenditure S Liu, TH Kim, DA Franklin, Y Zhang Cell reports 18 (4), 1005-1018, 2017 | 56 | 2017 |
| p53 regulates the expression of LRP1 and apoptosis through a stress intensity-dependent MicroRNA feedback loop PL Leslie, DA Franklin, Y Liu, Y Zhang Cell reports 24 (6), 1484-1495, 2018 | 35 | 2018 |
| MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC DA Franklin, JT Sharick, PI Ericsson-Gonzalez, V Sanchez, PT Dean, ... JCI insight 5 (15), 2020 | 27 | 2020 |
| MEK inhibition activates STAT signaling to increase breast cancer immunogenicity via MHC-I expression DA Franklin, JL James, ML Axelrod, JM Balko Cancer Drug Resistance 3 (3), 603, 2020 | 24 | 2020 |
| p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B J Di, J Tang, H Qian, DA Franklin, C Deisenroth, Y Itahana, J Zheng, ... Oncotarget 8 (39), 64657, 2017 | 13 | 2017 |
| Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway DA Franklin, S Liu, A Jin, P Cui, Z Guo, KC Arend, NJ Moorman, S He, ... Journal of Biological Chemistry 299 (1), 2023 | 4 | 2023 |
| Extra-ribosome functions of ribosomal proteins DA Franklin, Y Zhang Academic Press, 2016 | 4 | 2016 |
| Synthesis and optimization of new 3, 6-disubstitutedindole derivatives and their evaluation as anticancer agents targeting the MDM2/MDMX complex MS Rezk, M Abdel-Halim, A Keeton, D Franklin, M Bauer, FM Boeckler, ... Chemical and Pharmaceutical Bulletin 64 (1), 34-41, 2016 | 4 | 2016 |
| Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation JD Sanford, D Franklin, GA Grois, A Jin, Y Zhang Journal of Biological Chemistry 299 (7), 2023 | 3 | 2023 |
| Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway D Franklin, Y Zhang Molecular & Cellular Oncology 5 (3), e1302904, 2018 | 2 | 2018 |
| ADP-and ATP-mimetics derived from 2'(3')-C-methyladenosine as human P2Y1 and P2Y2 receptor ligands L Cappellacci, R Petrelli, P Vita, I Torquati, KA Jacobson, MO Barrett, ... PURINERGIC SIGNALLING 8 (1), 143-143, 2012 | 1 | 2012 |
| A CD33 antigen targeted Gamma Delta T-cell engager in combination with zoledronate promotes Vg9Vd2+ T cell proliferation and cytotoxicity against acute … AY Lai, C Wang, DC Baiu, K Smith, A Patel, K Evans, N Murr, D Franklin, ... Cancer Research 84 (6_Supplement), 6722-6722, 2024 | | 2024 |
| Rapid serial killing of target cells by Vγ9Vδ2 T Cells in cynomolgus macaques and humanized mice treated with a CD20-directed heterodimeric butyrophilin 2A1/3A1 fusion protein AY Lai, LE Gonzalez, N Murr, K Lenz, D Franklin, K Campbell, F Brewer, ... Cancer Research 83 (7_Supplement), 1815-1815, 2023 | | 2023 |
| Antigen targeted butyrophilin heterodimer-based bispecific engagers induce Vγ9δ2+ T cell-mediated anti-tumor activity D Franklin, A Lai, F Brewer, A Patel, K Evans, K Campbell, M Hussain, ... J Immunol 209 (8), 1475-1480, 2022 | | 2022 |
| MEK activation modulates immunosuppressive MDSCs and metabolic phenotypes in TNBC DA Franklin, JT Sharick, PI Ericsson-Gonzalez, V Sanchez, PT Dean, ... Cancer Research 79 (13_Supplement), 1511-1511, 2019 | | 2019 |
| Exploring the Metabolic Regulation of p53 from Ribosomal Proteins to Very Long Chain Fatty Acids DA Franklin The University of North Carolina at Chapel Hill, 2017 | | 2017 |
