Cardiac energy metabolism in heart failure GD Lopaschuk, QG Karwi, R Tian, AR Wende, ED Abel Circulation research 128 (10), 1487-1513, 2021 | 622 | 2021 |
Loss of metabolic flexibility in the failing heart QG Karwi, GM Uddin, KL Ho, GD Lopaschuk Frontiers in cardiovascular medicine 5, 68, 2018 | 342 | 2018 |
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ... Cardiovascular diabetology 18, 1-12, 2019 | 133 | 2019 |
AP39, a mitochondria‐targeting hydrogen sulfide (H2S) donor, protects against myocardial reperfusion injury independently of salvage kinase signalling QG Karwi, J Bornbaum, K Boengler, R Torregrossa, M Whiteman, ... British journal of pharmacology 174 (4), 287-301, 2017 | 95 | 2017 |
Ketone metabolism in the failing heart GD Lopaschuk, QG Karwi, KL Ho, S Pherwani, EB Ketema Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 79 | 2020 |
Ketones can become the major fuel source for the heart but do not increase cardiac efficiency KL Ho, QG Karwi, C Wagg, L Zhang, K Vo, T Altamimi, GM Uddin, ... Cardiovascular research 117 (4), 1178-1187, 2021 | 76 | 2021 |
Pharmacological postconditioning against myocardial infarction with a slow-releasing hydrogen sulfide donor, GYY4137 QG Karwi, M Whiteman, ME Wood, R Torregrossa, GF Baxter Pharmacological research 111, 442-451, 2016 | 72 | 2016 |
Adropin regulates cardiac energy metabolism and improves cardiac function and efficiency TR Altamimi, S Gao, QG Karwi, A Fukushima, S Rawat, CS Wagg, ... Metabolism 98, 37-48, 2019 | 61 | 2019 |
Influence of molecular weight and degree of deacetylation of low molecular weight chitosan on the bioactivity of oral insulin preparations NA Qinna, QG Karwi, N Al-Jbour, MA Al-Remawi, TM Alhussainy, ... Marine drugs 13 (4), 1710-1725, 2015 | 61 | 2015 |
Pre- and postconditioning the heart with hydrogen sulfide (H2S) against ischemia/reperfusion injury in vivo: a systematic review and meta-analysis QG Karwi, JS Bice, GF Baxter Basic research in cardiology 113, 1-21, 2018 | 53 | 2018 |
Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction QG Karwi, L Zhang, CS Wagg, W Wang, M Ghandi, D Thai, H Yan, ... Cardiovascular Diabetology 18, 1-18, 2019 | 52 | 2019 |
Myocardial ketones metabolism in heart failure QG Karwi, D Biswas, T Pulinilkunnil, GD Lopaschuk Journal of cardiac failure 26 (11), 998-1005, 2020 | 51 | 2020 |
Concurrent diabetes and heart failure: interplay and novel therapeutic approaches QG Karwi, KL Ho, S Pherwani, EB Ketema, Q Sun, GD Lopaschuk Cardiovascular Research 118 (3), 686-715, 2022 | 50 | 2022 |
Insulin directly stimulates mitochondrial glucose oxidation in the heart QG Karwi, CS Wagg, TR Altamimi, GM Uddin, KL Ho, AM Darwesh, ... Cardiovascular diabetology 19, 1-14, 2020 | 44 | 2020 |
The contribution of cardiac fatty acid oxidation to diabetic cardiomyopathy severity QG Karwi, Q Sun, GD Lopaschuk Cells 10 (11), 3259, 2021 | 41 | 2021 |
Metabolic, structural and biochemical changes in diabetes and the development of heart failure KL Ho, QG Karwi, D Connolly, S Pherwani, EB Ketema, JR Ussher, ... Diabetologia 65 (3), 411-423, 2022 | 39 | 2022 |
Weight loss enhances cardiac energy metabolism and function in heart failure associated with obesity QG Karwi, L Zhang, TR Altamimi, CS Wagg, V Patel, GM Uddin, AR Joerg, ... Diabetes, Obesity and Metabolism 21 (8), 1944-1955, 2019 | 38 | 2019 |
Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve TR Altamimi, QG Karwi, GM Uddin, A Fukushima, JQ Kwong, ... Journal of molecular and cellular cardiology 127, 223-231, 2019 | 36 | 2019 |
Branched-chain amino acid metabolism in the failing heart QG Karwi, GD Lopaschuk Cardiovascular Drugs and Therapy 37 (2), 413-420, 2023 | 35 | 2023 |
Allosteric, transcriptional and post-translational control of mitochondrial energy metabolism QG Karwi, AR Jörg, GD Lopaschuk Biochemical Journal 476 (12), 1695-1712, 2019 | 31 | 2019 |