In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies EA Fayed, YA Ammar, A Ragab, NA Gohar, ABM Mehany, AM Farrag Bioorganic Chemistry 100, 103951, 2020 | 51 | 2020 |
Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents EA Fayed, SI Eissa, AH Bayoumi, NA Gohar, ABM Mehany, YA Ammar Molecular diversity 23, 165-181, 2019 | 35 | 2019 |
Development of new spiro [1, 3] dithiine-4, 11′-indeno [1, 2-b] quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation A Ragab, MS Abusaif, NA Gohar, DS Aboul-Magd, EA Fayed, YA Ammar Bioorganic Chemistry 131, 106307, 2023 | 26 | 2023 |
Upregulation of BAX and caspase‐3, as well as downregulation of Bcl‐2 during treatment with indeno[1,2‐b]quinoxalin derivatives, mediated apoptosis in human … EA Fayed, NA Gohar, AM Farrag, YA Ammar Archiv der Pharmazie 355 (5), 2100454, 2022 | 17 | 2022 |
Novel fluorinated pyrazole-based heterocycles scaffold: cytotoxicity, in silico studies and molecular modelling targeting double mutant EGFR L858R/T790M as … EA Fayed, NA Gohar, AH Bayoumi, YA Ammar Medicinal Chemistry Research 32 (2), 369-388, 2023 | 9 | 2023 |
Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α-amylase, and α-glucosidase: synthesis, molecular docking, and … NA Gohar, EA Fayed, Y A. Ammar, O A. Abu Ali, A Ragab, AM Mahfoz, ... Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2367128, 2024 | 1 | 2024 |