| Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2 KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye, DM Kranz, ... Science 369 (6508), 1261-1265, 2020 | 568 | 2020 |
| Engineering interferons and interleukins for cancer immunotherapy PG Holder, SA Lim, CS Huang, P Sharma, YS Dagdas, B Bulutoglu, ... Advanced drug delivery reviews 182, 114112, 2022 | 74 | 2022 |
| Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides P Sharma, VVVR Marada, Q Cai, M Kizerwetter, Y He, SP Wolf, ... Proceedings of the National Academy of Sciences 117 (26), 15148-15159, 2020 | 37 | 2020 |
| Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity P Sharma, DM Kranz Journal of Biological Chemistry 293 (5), 1820-1834, 2018 | 33 | 2018 |
| Multiple cancer-specific antigens are targeted by a chimeric antibody receptor on a single cancer cell Y He, K Schreiber, SP Wolf, F Wen, C Steentoft, J Zerweck, M Steiner, ... JCI insight 4 (21), 2019 | 32 | 2019 |
| Recent advances in T-cell engineering for use in immunotherapy P Sharma, DM Kranz F1000Research 5, 2016 | 23 | 2016 |
| Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens P Sharma, N Wang, DM Kranz Toxins 6 (2), 556-574, 2014 | 21 | 2014 |
| Generation of genetically stable transformants by Agrobacterium using tomato floral buds MS Sharada, A Kumari, AK Pandey, S Sharma, P Sharma, Y Sreelakshmi, ... Plant Cell, Tissue and Organ Culture (PCTOC) 129, 299-312, 2017 | 19 | 2017 |
| T-cell receptors engineered de novo for peptide specificity can mediate optimal T-cell activity without self cross-reactivity P Sharma, DT Harris, JD Stone, DM Kranz Cancer Immunology Research, canimm. 0035.2019, 2019 | 14 | 2019 |
| A multiplex assay for detection of staphylococcal and streptococcal exotoxins P Sharma, N Wang, AS Chervin, CL Quinn, JD Stone, DM Kranz PloS one 10 (8), e0135986, 2015 | 7 | 2015 |
| Characterization of the Staphylococcal enterotoxin A: Vβ receptor interaction using human receptor fragments engineered for high affinity P Sharma, S Postel, EJ Sundberg, DM Kranz Protein Engineering, Design & Selection 26 (12), 781-789, 2013 | 7 | 2013 |
| Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model DRE Ranoa, P Sharma, CP Schane, AN Lewis, E Valdez, VVVR Marada, ... Journal for Immunotherapy of Cancer 11 (5), 2023 | 5 | 2023 |
| T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy P Sharma, DM Kranz Critical Reviews™ in Immunology 39 (2), 2019 | 2 | 2019 |
| i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists MG Romei, B Leonard, ZB Katz, D Le, Y Yang, ES Day, CW Koo, ... Nature Communications 15 (1), 642, 2024 | 1 | 2024 |
| Engineering Proteins by Combining Deep Mutational Scanning and Yeast Display P Sharma, E Procko, DM Kranz Yeast Surface Display, 117-142, 2022 | 1 | 2022 |
| Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen P Sharma, VVVR Marada, M Kizerwetter, CP Schane, Y He, SP Wolf, ... Cancer Research 80 (16 Supplement), 3238-3238, 2020 | | 2020 |
| Cancer treatment with 237 car-t cell based therapeutics recognizing the tn epitope PS Hans Schreiber, David Kranz, Karin Schreiber, Yanran He WO Patent WO2020056023A1, 2020 | | 2020 |
| Convergence of the specificity and cross-reactivity of multiple T cell receptors isolated against a single cancer peptide/HLA complex P Sharma, DT Harris, MV Hager, DM Kranz Cancer Research 78 (13_Supplement), 3581-3581, 2018 | | 2018 |
| Engineering soluble, high affinity T cell receptor domains for detection of staphylococcal and streptococcal exotoxins P Sharma University of Illinois at Urbana-Champaign, 2015 | | 2015 |
David Kranz在 illinois.edu 的电子邮件经过验证
