GSK3 inhibitor-loaded osteotropic Pluronic hydrogel effectively mitigates periodontal tissue damage associated with experimental periodontitis Y Almoshari, R Ren, H Zhang, Z Jia, X Wei, N Chen, G Li, S Ryu, SM Lele, ... Biomaterials 261, 120293, 2020 | 58 | 2020 |
Thermoresponsive hydrogel-based local delivery of simvastatin for the treatment of periodontitis N Chen, R Ren, X Wei, R Mukundan, G Li, X Xu, G Zhao, Z Zhao, SM Lele, ... Molecular pharmaceutics 18 (5), 1992-2003, 2021 | 36 | 2021 |
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain G Zhao, R Ren, X Wei, Z Jia, N Chen, Y Sun, Z Zhao, SM Lele, HA Zhong, ... Journal of Controlled Release 339, 484-497, 2021 | 27 | 2021 |
Dexamethasone prodrug nanomedicine (ZSJ-0228) treatment significantly reduces lupus nephritis in mice without measurable side effects—A 5-month study Z Zhao, Z Jia, KW Foster, X Wei, F Qiao, H Jiang, Y Jin, G Li, N Chen, ... Nanomedicine: Nanotechnology, Biology and Medicine 31, 102302, 2021 | 12 | 2021 |
Sympathetic innervation regulates osteocyte‐mediated cortical bone resorption during lactation Q Guo, N Chen, C Qian, C Qi, K Noller, M Wan, X Liu, W Zhang, P Cahan, ... Advanced Science 10 (18), 2207602, 2023 | 9 | 2023 |
Head-to-head comparative pharmacokinetic and biodistribution (PK/BD) study of two dexamethasone prodrug nanomedicines on lupus-prone NZB/WF1 mice X Wei, G Zhao, X Wang, N Gautam, Z Jia, Z Zhao, D Kong, F Zhang, ... Nanomedicine: Nanotechnology, Biology and Medicine 29, 102266, 2020 | 9 | 2020 |
Macromolecular dexamethasone prodrug ameliorates neuroinflammation and prevents bone loss associated with traumatic brain injury X Wei, G Zhao, Z Jia, Z Zhao, N Chen, Y Sun, M Kelso, G Rathore, ... Molecular pharmaceutics 19 (11), 4000-4009, 2022 | 7 | 2022 |
Polymeric dexamethasone prodrugs attenuate lupus nephritis in MRL/lpr mice with reduced glucocorticoid toxicity Z Zhao, H Jiang, X Xu, Z Jia, R Ren, KW Foster, X Wei, N Chen, ... Nanomedicine: Nanotechnology, Biology and Medicine 44, 102579, 2022 | 7 | 2022 |
Unloading‐Induced skeletal interoception alters hypothalamic signaling to promote bone loss and fat metabolism Q Guo, N Chen, K Patel, M Wan, J Zheng, X Cao Advanced Science 10 (35), 2305042, 2023 | 6 | 2023 |
Preclinical dose-escalation study of ZSJ-0228, a polymeric dexamethasone prodrug, in the treatment of murine lupus nephritis Z Zhao, X Xu, H Jiang, KW Foster, Z Jia, X Wei, N Chen, SR Goldring, ... Molecular pharmaceutics 18 (11), 4188-4197, 2021 | 5 | 2021 |
Single dose thermoresponsive dexamethasone prodrug completely mitigates joint pain for 15 weeks in a murine model of osteoarthritis N Chen, X Wei, G Zhao, Z Jia, X Fu, H Jiang, X Xu, Z Zhao, P Singh, ... Nanomedicine: Nanotechnology, Biology and Medicine 57, 102735, 2024 | 1 | 2024 |
Thermoresponsive Polymeric Hydromorphone Prodrug Provides Sustained Local Analgesia without Apparent Adverse Effects Z Jia, X Wei, N Chen, X Xu, G Zhao, X Fu, H Wang, MB Goldring, ... Molecular Pharmaceutics 21 (4), 1838-1847, 2024 | | 2024 |
The Development of Thermoresponsive Polymeric Simvastatin Prodrug for the Treatment of Experimental Periodontitis in Rats X Xu, Z Jia, N Chen, SM Lele, S Arash, RA Reinhardt, AC Killeen, D Wang Molecular Pharmaceutics 20 (11), 5631-5645, 2023 | | 2023 |
Macromolecular Dexamethasone Prodrug Ameliorates Neuroinflammation and Prevents Bone Loss Associated with Traumatic Brain Injury G Zhao, Z Jia, Z Zhao, N Chen, Y Sun, M Kelso, G Rathore, D Wang ANNALS OF NEUROLOGY 92, S186-S188, 2022 | | 2022 |
Hydrogel drug delivery composition D Wang, Y Almoshari, R Ren, N Chen US Patent App. 17/604,659, 2022 | | 2022 |
Development of a Local Injectable Hydrogel Formulation to Accelerate the Healing of Delayed Fracture Union N Chen, M Akhter, R Ren, X Wei, G Zhao, H Jiang, Y Jin, Z Jia, ... JOURNAL OF BONE AND MINERAL RESEARCH 37, 199-199, 2022 | | 2022 |
The Development of Thermoresponsive Hydrogel-Based Drug Delivery Systems for the Treatment of Musculoskeletal Diseases N Chen | | 2022 |
A Macromolecular Tanshinone IIA Prodrug-Based Thermoresponsive Hydrogel Accelerates the Healing of Delayed Fracture Union N Chen, R Ren, X Wei, G Zhao, Y Jin, Z Jia, R Mukundan, Z Zhao, Y Sun, ... | | |