| Matrix elasticity regulates lamin-A, C phosphorylation and turnover with feedback to actomyosin A Buxboim, J Swift, J Irianto, KR Spinler, PCDP Dingal, A Athirasala, ... Current Biology 24 (16), 1909-1917, 2014 | 381 | 2014 |
| Mechanosensing by the nucleus: From pathways to scaling relationships S Cho, J Irianto, DE Discher Journal of Cell Biology 216 (2), 305-315, 2017 | 374 | 2017 |
| Stem cell differentiation is regulated by extracellular matrix mechanics LR Smith, S Cho, DE Discher Physiology 33 (1), 16-25, 2018 | 262 | 2018 |
| Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell-cycle arrest S Cho, M Vashisth, A Abbas, S Majkut, K Vogel, Y Xia, IL Ivanovska, ... Developmental cell 49 (6), 920-935. e5, 2019 | 244 | 2019 |
| Single-cell RNA sequencing in cardiovascular development, disease and medicine DT Paik, S Cho, L Tian, HY Chang, JC Wu Nature Reviews Cardiology 17 (8), 457-473, 2020 | 215 | 2020 |
| Nuclear rupture at sites of high curvature compromises retention of DNA repair factors Y Xia, IL Ivanovska, K Zhu, L Smith, J Irianto, CR Pfeifer, CM Alvey, J Ji, ... Journal of Cell Biology 217 (11), 3796-3808, 2018 | 155 | 2018 |
| Tight coupling between nucleus and cell migration through the perinuclear actin cap DH Kim, D Wirtz Biophysical Journal 106 (2), 43a, 2014 | 133 | 2014 |
| Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor D Dingal, AM Bradshaw, S Cho, M Raab, A Buxboim, J Swift, DE Discher Nature materials 14 (9), 951, 2015 | 124 | 2015 |
| SIRPA-inhibited, marrow-derived macrophages engorge, accumulate, and differentiate in antibody-targeted regression of solid tumors CM Alvey, KR Spinler, J Irianto, CR Pfeifer, B Hayes, Y Xia, S Cho, ... Current Biology 27 (14), 2065-2077. e6, 2017 | 123 | 2017 |
| Matrix mechanosensing: from scaling concepts in’omics data to mechanisms in the nucleus, regeneration, and cancer DE Discher, L Smith, S Cho, M Colasurdo, AJ García, S Safran Annual review of biophysics 46 (1), 295-315, 2017 | 94 | 2017 |
| Mechanosensing of matrix by stem cells: From matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo L Smith, S Cho, DE Discher Seminars in cell & developmental biology 71, 84-98, 2017 | 81 | 2017 |
| Challenges and opportunities for the next generation of cardiovascular tissue engineering S Cho, DE Discher, KW Leong, G Vunjak-Novakovic, JC Wu Nature Methods 19 (9), 1064-1071, 2022 | 73 | 2022 |
| Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation IL Ivanovska, J Swift, K Spinler, D Dingal, S Cho, DE Discher Molecular biology of the cell 28 (14), 2010-2022, 2017 | 69 | 2017 |
| Mechanical signaling coordinates the embryonic heartbeat AJL K Chiou, JW Rocks, CY Chen, S Cho, KE Merkus, A Rajaratnam, P Robison, M ... Proceedings of the National Academy of Sciences 113 (32), 8939-8944, 2016 | 61* | 2016 |
| Tension in fibrils suppresses their enzymatic degradation–A molecular mechanism for ‘use it or lose it’ K Saini, S Cho, LJ Dooling, DE Discher Matrix Biology 85, 34-46, 2020 | 60 | 2020 |
| Reconstructing the heart using iPSCs: Engineering strategies and applications S Cho, C Lee, MA Skylar-Scott, SC Heilshorn, JC Wu Journal of Molecular and Cellular Cardiology 157, 56-65, 2021 | 44 | 2021 |
| Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A, C in iPS-derived mesenchymal stem cells S Cho, A Abbas, J Irianto, IL Ivanovska, Y Xia, M Tewari, DE Discher Nucleus 9 (1), 235-250, 2018 | 37 | 2018 |
| Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate CR Pfeifer, MP Tobin, S Cho, M Vashisth, LJ Dooling, LL Vazquez, ... Nucleus 13 (1), 130-144, 2022 | 25 | 2022 |
| Nuclear mechanosensing Y Xia, CR Pfeifer, S Cho, DE Discher, J Irianto Emerging topics in life sciences 2 (5), 713-725, 2018 | 25 | 2018 |
| Scaling concepts in ‘omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis M Vashisth, S Cho, J Irianto, Y Xia, M Wang, B Hayes, D Wieland, R Wells, ... Proceedings of the National Academy of Sciences 118 (48), e2112940118, 2021 | 17 | 2021 |
Dennis DischerUniversity of Pennsylvania在 seas.upenn.edu 的电子邮件经过验证
