Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin B Lehnertz, Y Ueda, AAHA Derijck, U Braunschweig, L Perez-Burgos, ... Current Biology 13 (14), 1192-1200, 2003 | 1508 | 2003 |
Mubritinib targets the electron transport chain complex I and reveals the landscape of OXPHOS dependency in acute myeloid leukemia I Baccelli, Y Gareau, B Lehnertz, S Gingras, JF Spinella, S Corneau, ... Cancer cell 36 (1), 84-99. e8, 2019 | 212 | 2019 |
EPCR expression marks UM171-expanded CD34+ cord blood stem cells I Fares, J Chagraoui, B Lehnertz, T MacRae, N Mayotte, E Tomellini, ... Blood, The Journal of the American Society of Hematology 129 (25), 3344-3351, 2017 | 192 | 2017 |
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study S Cohen, J Roy, S Lachance, JS Delisle, A Marinier, L Busque, DC Roy, ... The Lancet Haematology 7 (2), e134-e145, 2020 | 191 | 2020 |
Control of the hippo pathway by Set7-dependent methylation of Yap MJ Oudhoff, SA Freeman, AL Couzens, F Antignano, E Kuznetsova, ... Developmental cell 26 (2), 188-194, 2013 | 180 | 2013 |
Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function B Lehnertz, JP Northrop, F Antignano, K Burrows, S Hadidi, SC Mullaly, ... Journal of Experimental Medicine 207 (5), 915-922, 2010 | 176 | 2010 |
The methyltransferase G9a regulates HoxA9-dependent transcription in AML B Lehnertz, C Pabst, L Su, M Miller, F Liu, L Yi, R Zhang, J Krosl, E Yung, ... Genes & development 28 (4), 317-327, 2014 | 157 | 2014 |
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing DC Leung, KB Dong, IA Maksakova, P Goyal, R Appanah, S Lee, ... Proceedings of the National Academy of Sciences 108 (14), 5718-5723, 2011 | 142 | 2011 |
p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice B Lehnertz, JC Rogalski, FM Schulze, L Yi, S Lin, J Kast, FMV Rossi Molecular cell 43 (4), 673-680, 2011 | 86 | 2011 |
Genetic characterization of ABT-199 sensitivity in human AML R Bisaillon, C Moison, C Thiollier, J Krosl, ME Bordeleau, B Lehnertz, ... Leukemia 34 (1), 63-74, 2020 | 79 | 2020 |
H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations B Lehnertz, YW Zhang, I Boivin, N Mayotte, E Tomellini, J Chagraoui, ... Blood, The Journal of the American Society of Hematology 130 (20), 2204-2214, 2017 | 76 | 2017 |
Integrin-α3 is a functional marker of ex vivo expanded human long-term hematopoietic stem cells E Tomellini, I Fares, B Lehnertz, J Chagraoui, N Mayotte, T MacRae, ... Cell Reports 28 (4), 1063-1073. e5, 2019 | 61 | 2019 |
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal J Chagraoui, B Lehnertz, S Girard, JF Spinella, I Fares, E Tomellini, ... PLoS One 14 (11), e0224900, 2019 | 53 | 2019 |
HLF expression defines the human hematopoietic stem cell state B Lehnertz, J Chagraoui, T MacRae, E Tomellini, S Corneau, N Mayotte, ... Blood, The Journal of the American Society of Hematology 138 (25), 2642-2654, 2021 | 50 | 2021 |
Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity L Simon, VP Lavallée, ME Bordeleau, J Krosl, I Baccelli, G Boucher, ... Clinical cancer research 23 (22), 6969-6981, 2017 | 49 | 2017 |
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells YW Zhang, J Mess, N Aizarani, P Mishra, C Johnson, MC Romero-Mulero, ... Nature cell biology 24 (7), 1038-1048, 2022 | 41 | 2022 |
Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition C Moison, VP Lavallée, C Thiollier, B Lehnertz, I Boivin, N Mayotte, ... Blood advances 3 (4), 552-563, 2019 | 28 | 2019 |
Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression N Higashihori, B Lehnertz, A Sampaio, TM Underhill, F Rossi, ... Journal of dental research 96 (10), 1136-1144, 2017 | 26 | 2017 |
UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis R Aucagne, S Girard, N Mayotte, B Lehnertz, S Lopes‐Paciencia, ... The FASEB Journal 31 (11), 5012-5018, 2017 | 21 | 2017 |
HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition C Moison, JF Spinella, J Chagraoui, VP Lavallée, B Lehnertz, C Thiollier, ... Blood Advances 6 (16), 4793-4806, 2022 | 10 | 2022 |