Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2 MJ Schmeisser, E Ey, S Wegener, J Bockmann, AV Stempel, A Kuebler, ... Nature 486 (7402), 256-260, 2012 | 691 | 2012 |
Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments CS Leblond, C Nava, A Polge, J Gauthier, G Huguet, S Lumbroso, ... PLoS genetics 10 (9), e1004580, 2014 | 622 | 2014 |
Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies AM Grabrucker, MJ Schmeisser, M Schoen, TM Boeckers Trends in cell biology 21 (10), 594-603, 2011 | 253 | 2011 |
Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice S Peter, MM Ten Brinke, J Stedehouder, CM Reinelt, B Wu, H Zhou, ... Nature communications 7 (1), 12627, 2016 | 197 | 2016 |
Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders S Grabrucker, L Jannetti, M Eckert, S Gaub, R Chhabra, S Pfaender, ... Brain 137 (1), 137-152, 2014 | 187 | 2014 |
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice C Vicidomini, L Ponzoni, D Lim, MJ Schmeisser, D Reim, N Morello, ... Molecular psychiatry 22 (5), 689-702, 2017 | 155 | 2017 |
IκB kinase/nuclear factor κB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling MJ Schmeisser, B Baumann, S Johannsen, GF Vindedal, V Jensen, ... Journal of Neuroscience 32 (16), 5688-5703, 2012 | 151 | 2012 |
In‐depth protein profiling of the postsynaptic density from mouse hippocampus using data‐independent acquisition proteomics U Distler, MJ Schmeisser, A Pelosi, D Reim, J Kuharev, R Weiczner, ... Proteomics 14 (21-22), 2607-2613, 2014 | 108 | 2014 |
Scaffold proteins at the postsynaptic density C Verpelli, MJ Schmeisser, C Sala, TM Boeckers Synaptic plasticity: dynamics, development and disease, 29-61, 2012 | 105 | 2012 |
Neurobiology of autism gene products: towards pathogenesis and drug targets KTE Kleijer, MJ Schmeisser, DD Krueger, TM Boeckers, P Scheiffele, ... Psychopharmacology 231, 1037-1062, 2014 | 96 | 2014 |
Super-resolution microscopy reveals presynaptic localization of the ALS/FTD related protein FUS in hippocampal neurons M Schoen, JM Reichel, M Demestre, S Putz, D Deshpande, C Proepper, ... Frontiers in cellular neuroscience 9, 496, 2016 | 89 | 2016 |
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold AM Grabrucker, MJ Schmeisser, PT Udvardi, M Arons, M Schoen, ... Molecular neurodegeneration 6, 1-20, 2011 | 78 | 2011 |
Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder D Reim, U Distler, S Halbedl, C Verpelli, C Sala, J Bockmann, S Tenzer, ... Frontiers in molecular neuroscience 10, 26, 2017 | 73 | 2017 |
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation S Grabrucker, C Proepper, K Mangus, M Eckert, R Chhabra, ... Experimental neurology 253, 126-137, 2014 | 70 | 2014 |
Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID DM Cochoy, A Kolevzon, Y Kajiwara, M Schoen, M Pascual-Lucas, ... Molecular autism 6, 1-13, 2015 | 69 | 2015 |
Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-β-catenin at excitatory synapses MJ Schmeisser, AM Grabrucker, J Bockmann, TM Boeckers Journal of Biological Chemistry 284 (42), 29146-29157, 2009 | 66 | 2009 |
Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport G Tosi, A Vilella, R Chhabra, MJ Schmeisser, TM Boeckers, B Ruozi, ... Journal of controlled Release 177, 96-107, 2014 | 63 | 2014 |
An SK3 channel/nWASP/Abi-1 complex is involved in early neurogenesis S Liebau, J Steinestel, L Linta, A Kleger, A Storch, M Schoen, K Steinestel, ... PloS one 6 (3), e18148, 2011 | 56 | 2011 |
Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals S Halbedl, M Schoen, MS Feiler, TM Boeckers, MJ Schmeisser Journal of neurochemistry 137 (1), 26-32, 2016 | 55 | 2016 |
PRG-1 regulates synaptic plasticity via intracellular PP2A/β1-integrin signaling X Liu, J Huai, H Endle, L Schlüter, W Fan, Y Li, S Richers, H Yurugi, ... Developmental cell 38 (3), 275-290, 2016 | 47 | 2016 |