Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53 HJ Shin, HK Kwon, JH Lee, X Gui, A Achek, JH Kim, S Choi Scientific reports 5 (1), 15798, 2015 | 125 | 2015 |
Toll-like receptors: promising therapeutic targets for inflammatory diseases A Achek, D Yesudhas, S Choi Archives of pharmacal research 39, 1032-1049, 2016 | 104 | 2016 |
WNT signaling and chondrocytes: from cell fate determination to osteoarthritis physiopathology N Sassi, L Laadhar, M Allouche, A Achek, M Kallel-Sellami, S Makni, ... Journal of Receptors and Signal Transduction 34 (2), 73-80, 2014 | 82 | 2014 |
Server and units IM Mergler US Patent 6,942,575, 2005 | 49 | 2005 |
TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation S Park, HJ Shin, M Shah, HY Cho, MA Anwar, A Achek, HK Kwon, B Lee, ... Biomaterials 126, 49-60, 2017 | 48 | 2017 |
Linear and rationally designed stapled peptides abrogate TLR4 pathway and relieve inflammatory symptoms in rheumatoid arthritis rat model A Achek, M Shah, JY Seo, HK Kwon, X Gui, HJ Shin, EY Cho, BS Lee, ... Journal of medicinal chemistry 62 (14), 6495-6511, 2019 | 33 | 2019 |
A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice HK Kwon, MC Patra, HJ Shin, X Gui, A Achek, S Panneerselvam, DJ Kim, ... Experimental & Molecular Medicine 51 (4), 1-19, 2019 | 30 | 2019 |
A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models A Achek, HK Kwon, MC Patra, M Shah, R Hong, WH Lee, WY Baek, ... EBioMedicine 52, 2020 | 20 | 2020 |
Toll‐like receptor 2 antagonists identified through virtual screening and experimental validation P Durai, HJ Shin, A Achek, HK Kwon, RG Govindaraj, S Panneerselvam, ... The FEBS journal 284 (14), 2264-2283, 2017 | 20 | 2017 |
The αC helix of TIRAP holds therapeutic potential in TLR-mediated autoimmune diseases M Shah, GY Kim, A Achek, EY Cho, WY Baek, YS Choi, WH Lee, DJ Kim, ... Biomaterials 245, 119974, 2020 | 16 | 2020 |
A novel small-molecule inhibitor of endosomal TLRs reduces inflammation and alleviates autoimmune disease symptoms in murine models MC Patra, A Achek, GY Kim, S Panneerselvam, HJ Shin, WY Baek, ... Cells 9 (7), 1648, 2020 | 13 | 2020 |
Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study S Panneerselvam, P Durai, D Yesudhas, A Achek, HK Kwon, S Choi RSC advances 6 (103), 100804-100819, 2016 | 6 | 2016 |
Accelerated NLRP3 inflammasome-inhibitory peptide design using a recurrent neural network model and molecular dynamics simulations B Ahmad, A Achek, M Farooq, S Choi Computational and Structural Biotechnology Journal 21, 4825-4835, 2023 | 1 | 2023 |
Peptide therapeutics for autoimmune diseases and inflammatory diseases SD Choi, CH Suh, W Kim, S Masaud, A Achek, KIM Giyoung, JY Cheong, ... US Patent App. 17/627,018, 2022 | | 2022 |
Novel tlr2 antagonists SD Choi, P Durai, A Achek US Patent App. 15/578,086, 2018 | | 2018 |