Monounsaturated fatty acid–enriched high-fat diets impede adipose NLRP3 inflammasome–mediated IL-1β secretion and insulin resistance despite obesity OM Finucane, CL Lyons, AM Murphy, CM Reynolds, R Klinger, NP Healy, ... Diabetes 64 (6), 2116-2128, 2015 | 299 | 2015 |
Fatty acids and NLRP3 inflammasome–mediated inflammation in metabolic tissues JC Ralston, CL Lyons, EB Kennedy, AM Kirwan, HM Roche Annual review of nutrition 37 (1), 77-102, 2017 | 193 | 2017 |
Nutritional modulation of AMPK-impact upon metabolic-inflammation CL Lyons, HM Roche International journal of molecular sciences 19 (10), 3092, 2018 | 151 | 2018 |
Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome AA Cooke, RM Connaughton, CL Lyons, AM McMorrow, HM Roche European journal of pharmacology 785, 207-214, 2016 | 136 | 2016 |
Metabolic inflammation-differential modulation by dietary constituents CL Lyons, EB Kennedy, HM Roche Nutrients 8 (5), 247, 2016 | 114 | 2016 |
Serotonergic regulation of insulin secretion LR Cataldo Bascuñan, C Lyons, H Bennet, I Artner, M Fex Acta Physiologica 225 (1), e13101, 2019 | 65 | 2019 |
High-density lipoprotein proteomic composition, and not efflux capacity, reflects differential modulation of reverse cholesterol transport by saturated and monounsaturated fat … M O’Reilly, E Dillon, W Guo, O Finucane, A McMorrow, A Murphy, C Lyons, ... Circulation 133 (19), 1838-1850, 2016 | 61 | 2016 |
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α–Dependent inflammation GA Tynan, CH Hearnden, E Oleszycka, CL Lyons, G Coutts, J O’Connell, ... Diabetes 63 (6), 2037-2050, 2014 | 44 | 2014 |
Interactions between differential fatty acids and inflammatory stressors—impact on metabolic health AM Murphy, CL Lyons, OM Finucane, HM Roche Prostaglandins, Leukotrienes and Essential Fatty Acids 92, 49-55, 2015 | 33 | 2015 |
A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome‐mediated inflammation and improving insulin signaling NP Healy, AM Kirwan, MA McArdle, K Holohan, AB Nongonierma, ... Molecular nutrition & food research 60 (11), 2421-2432, 2016 | 30 | 2016 |
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets K Bacos, A Perfilyev, A Karagiannopoulos, E Cowan, JK Ofori, ... The Journal of clinical investigation 133 (4), 2023 | 20 | 2023 |
Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction JC Ralston, MS Nguyen-Tu, CL Lyons, AA Cooke, AM Murphy, A Falvey, ... British Journal of Nutrition 124 (3), 247-255, 2020 | 12 | 2020 |
Monounsaturated fatty acids impede inflammation partially through activation of AMPK CL Lyons, OF Finucane, AM Murphy, AA Cooke, B Viollet, PM Vieira, ... The FASEB Journal 30, 296.5-296.5, 2016 | 12 | 2016 |
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion G Verma, A Bowen, S Gheibi, A Hamilton, S Muthukumar, LR Cataldo, ... Journal of Biological Chemistry 298 (3), 2022 | 10 | 2022 |
Dietary substitution of saturated with monounsaturated fatty acids within high-fat diets attenuates hyperinsulinemia and pancreatic islet dysfunction JC Ralston, CL Lyons, AA Cooke, M Aoife, A Falvey, OM Finucane, ... Br. J. Nutr, 1-22, 2020 | 2 | 2020 |
Pancreatic islet dysfunction is partially attenuated by replacement of dietary saturated fatty acids with monounsaturated fatty acids JC Ralston, MS Nguyen-Tu, CL Lyons, AM Murphy, AA Cooke, A Falvey, ... Proceedings of the Nutrition Society 76 (OCE3), E55, 2017 | 2 | 2017 |
Next generation diabetes scientists shape global research culture: A reflective proposal from postdoctoral researchers in diabetes research MM Broadley, A Gonzalez‐Franquesa, A Jonsson, CB Christiansen, ... Acta Physiologica 229 (2), 2020 | 1 | 2020 |
Creating an Inclusive Academic Research Culture C Lyons, K Herzog, M Tata, N von der Lehr, S Jain | | 2021 |
Science not silence–a positive spin on negative results C Lyons, K Herzog | | 2021 |
DIMT1, a regulator of ribosomal biogenesis, controls β-cell protein synthesis, mitochondrial function and insulin secretion G Verma, A Bowen, A Hamilton, J Esguerra, A Karagiannopoulos, ... bioRxiv, 2020.09. 27.313262, 2020 | | 2020 |