Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation*♦ K Kuramoto, T Okamura, T Yamaguchi, TY Nakamura, S Wakabayashi, ... Journal of Biological Chemistry 287 (28), 23852-23863, 2012 | 254 | 2012 |
Autophagy differentially regulates insulin production and insulin sensitivity S Yamamoto, K Kuramoto, N Wang, X Situ, M Priyadarshini, W Zhang, ... Cell reports 23 (11), 3286-3299, 2018 | 141 | 2018 |
GSKJ4, a selective jumonji H3K27 demethylase inhibitor, effectively targets ovarian cancer stem cells H Sakaki, M Okada, K Kuramoto, H Takeda, H Watarai, S Suzuki, S Seino, ... Anticancer Research 35 (12), 6607-6614, 2015 | 69 | 2015 |
Deficiency of a lipid droplet protein, Perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction K Kuramoto, F Sakai, N Yoshinori, TY Nakamura, S Wakabayashi, ... Molecular and Cellular Biology 34 (14), 2721-2731, 2014 | 67 | 2014 |
The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo M Okada, K Kuramoto, H Takeda, H Watarai, H Sakaki, S Seino, M Seino, ... Oncotarget 7 (19), 27021, 2016 | 59 | 2016 |
Aripiprazole, an antipsychotic and partial dopamine agonist, inhibits cancer stem cells and reverses chemoresistance S Suzuki, M Okada, K Kuramoto, H Takeda, H Sakaki, H Watarai, ... Anticancer research 36 (10), 5153-5161, 2016 | 57 | 2016 |
Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells S Suzuki, M Okada, H Takeda, K Kuramoto, T Sanomachi, K Togashi, ... Oncotarget 9 (66), 32667, 2018 | 50 | 2018 |
Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells K Kuramoto, M Yamamoto, S Suzuki, T Sanomachi, K Togashi, S Seino, ... The FEBS journal 287 (10), 2023-2036, 2020 | 49 | 2020 |
Olanzapine, an atypical antipsychotic, inhibits survivin expression and sensitizes cancer cells to chemotherapeutic agents T Sanomachi, S Suzuki, K Kuramoto, H Takeda, H Sakaki, K Togashi, ... Anticancer research 37 (11), 6177-6188, 2017 | 42 | 2017 |
The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding K Kuramoto, YJ Kim, JH Hong, C He Cell reports 35 (8), 2021 | 37 | 2021 |
Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson’s disease, as an anti-cancer stem cell drug M Okada, H Takeda, H Sakaki, K Kuramoto, S Suzuki, T Sanomachi, ... Oncotarget 8 (55), 94872, 2017 | 37 | 2017 |
Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction K Kuramoto, S Suzuki, H Sakaki, H Takeda, T Sanomachi, S Seino, ... FEBS Open Bio 7 (6), 835-844, 2017 | 35 | 2017 |
Rho-associated protein kinase (ROCK) inhibitors inhibit survivin expression and sensitize pancreatic cancer stem cells to gemcitabine H Takeda, M Okada, S Suzuki, K Kuramoto, H Sakaki, H Watarai, ... Anticancer Research 36 (12), 6311-6318, 2016 | 32 | 2016 |
Impact of H3K27 demethylase inhibitor GSKJ4 on NSCLC cells alone and in combination with metformin H Watarai, M Okada, K Kuramoto, H Takeda, H Sakaki, S Suzuki, S Seino, ... Anticancer research 36 (11), 6083-6092, 2016 | 32 | 2016 |
Inhibition of the Lipid Droplet–Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties K Kuramoto, M Yamamoto, S Suzuki, K Togashi, T Sanomachi, ... Genes 12 (1), 99, 2021 | 31 | 2021 |
Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel M Seino, M Okada, H Sakaki, H Takeda, H Watarai, S Suzuki, S Seino, ... Oncology Reports 35 (1), 593-601, 2016 | 29 | 2016 |
Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise K Kuramoto, H Liang, JH Hong, C He Cell metabolism 35 (4), 620-632. e5, 2023 | 26 | 2023 |
Heart lipid droplets and lipid droplet-binding proteins: Biochemistry, physiology, and pathology T Osumi, K Kuramoto Experimental Cell Research 340 (2), 198-204, 2016 | 24 | 2016 |
AS602801, an anti-cancer stem cell drug candidate, suppresses gap-junction communication between lung cancer stem cells and astrocytes K Kuramoto, M Yamamoto, S Suzuki, T Sanomachi, K Togashi, S Seino, ... Anticancer research 38 (9), 5093-5099, 2018 | 23 | 2018 |
Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo H Takeda, M Okada, K Kuramoto, S Suzuki, H Sakaki, T Sanomachi, ... Oncotarget 8 (53), 90996, 2017 | 20 | 2017 |