Cyclohexylcarbamic acid 3 ‘-or 4 ‘-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure− activity relationships, and … M Mor, S Rivara, A Lodola, PV Plazzi, G Tarzia, A Duranti, A Tontini, ... Journal of medicinal chemistry 47 (21), 4998-5008, 2004 | 332 | 2004 |
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus JK Makara, M Mor, D Fegley, SI Szabó, S Kathuria, G Astarita, A Duranti, ... Nature neuroscience 8 (9), 1139-1141, 2005 | 266 | 2005 |
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation C Solorzano, C Zhu, N Battista, G Astarita, A Lodola, S Rivara, M Mor, ... Proceedings of the National Academy of Sciences 106 (49), 20966-20971, 2009 | 264 | 2009 |
Design, synthesis, and structure− activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors G Tarzia, A Duranti, A Tontini, G Piersanti, M Mor, S Rivara, PV Plazzi, ... Journal of medicinal chemistry 46 (12), 2352-2360, 2003 | 209 | 2003 |
MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential DP Zlotos, R Jockers, E Cecon, S Rivara, PA Witt-Enderby Journal of medicinal chemistry 57 (8), 3161-3185, 2014 | 203 | 2014 |
Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases S Rivara, FM Milazzo, G Giannini Future medicinal chemistry 8 (6), 647-680, 2016 | 179 | 2016 |
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand R Ochoa-Sanchez, S Comai, B Lacoste, FR Bambico, ... Journal of Neuroscience 31 (50), 18439-18452, 2011 | 147 | 2011 |
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice J LoVerme, A Duranti, A Tontini, G Spadoni, M Mor, S Rivara, N Stella, ... Bioorganic & medicinal chemistry letters 19 (3), 639-643, 2009 | 130 | 2009 |
2-[N-Acylamino(C1−C3)alkyl]indoles as MT1 Melatonin Receptor Partial Agonists, Antagonists, and Putative Inverse Agonists G Spadoni, C Balsamini, A Bedini, G Diamantini, B Di Giacomo, A Tontini, ... Journal of medicinal chemistry 41 (19), 3624-3634, 1998 | 127 | 1998 |
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices AR King, A Duranti, A Tontini, S Rivara, A Rosengarth, JR Clapper, ... Chemistry & biology 14 (12), 1357-1365, 2007 | 126 | 2007 |
Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties G Astarita, B Di Giacomo, S Gaetani, F Oveisi, TR Compton, S Rivara, ... Journal of Pharmacology and Experimental Therapeutics 318 (2), 563-570, 2006 | 112 | 2006 |
N-(Substituted-anilinoethyl)amides: Design, Synthesis, and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands S Rivara, A Lodola, M Mor, A Bedini, G Spadoni, V Lucini, M Pannacci, ... Journal of medicinal chemistry 50 (26), 6618-6626, 2007 | 101 | 2007 |
Melatonin receptor ligands: Synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study M Mor, S Rivara, C Silva, F Bordi, PV Plazzi, G Spadoni, G Diamantini, ... Journal of medicinal chemistry 41 (20), 3831-3844, 1998 | 99 | 1998 |
Analysis of Structure−Activity Relationships for MT2 Selective Antagonists by Melatonin MT1 and MT2 Receptor Models S Rivara, S Lorenzi, M Mor, PV Plazzi, G Spadoni, A Bedini, G Tarzia Journal of medicinal chemistry 48 (12), 4049-4060, 2005 | 92 | 2005 |
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study G Spadoni, C Balsamini, G Diamantini, B Di Giacomo, G Tarzia, M Mor, ... Journal of medicinal chemistry 40 (13), 1990-2002, 1997 | 91 | 1997 |
Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam R Ochoa-Sanchez, Q Rainer, S Comai, G Spadoni, A Bedini, S Rivara, ... Progress in neuro-psychopharmacology and biological psychiatry 39 (2), 318-325, 2012 | 89 | 2012 |
Irreversible inhibition of epidermal growth factor receptor activity by 3-aminopropanamides C Carmi, E Galvani, F Vacondio, S Rivara, A Lodola, S Russo, S Aiello, ... Journal of medicinal chemistry 55 (5), 2251-2264, 2012 | 83 | 2012 |
Melatonin receptor agonists: new options for insomnia and depression treatment G Spadoni, A Bedini, S Rivara, M Mor CNS neuroscience & therapeutics 17 (6), 733-741, 2011 | 82 | 2011 |
Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion C Carmi, A Cavazzoni, S Vezzosi, F Bordi, F Vacondio, C Silva, S Rivara, ... Journal of medicinal chemistry 53 (5), 2038-2050, 2010 | 77 | 2010 |
Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders S Rivara, M Mor, A Bedini, G Spadoni, G Tarzia Current topics in medicinal chemistry 8 (11), 954-968, 2008 | 77 | 2008 |