Salmonellae interactions with host processes DL LaRock, A Chaudhary, SI Miller Nature Reviews Microbiology 13 (4), 191-205, 2015 | 534 | 2015 |
IL-1β is an innate immune sensor of microbial proteolysis CN LaRock, J Todd, DL LaRock, J Olson, AJ O’Donoghue, ... Science Immunology 1 (2), eaah3539-eaah3539, 2016 | 143 | 2016 |
Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes DL LaRock, AF Johnson, S Wilde, JS Sands, MP Monteiro, CN LaRock Nature 605 (7910), 527-531, 2022 | 94 | 2022 |
Activation of a bacterial virulence protein by the GTPase RhoA M Christen, LH Coye, JS Hontz, DL LaRock, RA Pfuetzner, Megha, ... Science signaling 2 (95), ra71-ra71, 2009 | 58 | 2009 |
The Pseudomonas aeruginosa protease LasB directly activates IL-1β J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, ... EBioMedicine 60, 2020 | 39 | 2020 |
The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance J Munguia, DL LaRock, H Tsunemoto, J Olson, I Cornax, J Pogliano, ... Journal of molecular medicine 95, 1127-1136, 2017 | 39 | 2017 |
A Salmonella typhimurium-translocated glycerophospholipid: cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions DL LaRock, PS Brzovic, I Levin, MP Blanc, SI Miller Journal of Biological Chemistry 287 (35), 29654-29663, 2012 | 34 | 2012 |
Group A Streptococcus infection of the nasopharynx requires proinflammatory signaling through the interleukin-1 receptor DL LaRock, R Russell, AF Johnson, S Wilde, CN LaRock Infection and immunity 88 (10), 10.1128/iai. 00356-20, 2020 | 29 | 2020 |
Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea … JL Spinner, CO Jarrett, DL LaRock, SI Miller, CM Collins, BJ Hinnebusch BMC microbiology 12, 1-14, 2012 | 22 | 2012 |
Restoring endogenous repair mechanisms to heal chronic wounds with a multifunctional wound dressing RB Atashgah, A Ghasemi, M Raoufi, MA Abdollahifar, S Zanganeh, ... Molecular pharmaceutics 18 (8), 3171-3180, 2021 | 20 | 2021 |
Inflammasome inhibition blocks cardiac glycoside cell toxicity DL LaRock, JS Sands, E Ettouati, M Richard, PJ Bushway, ED Adler, ... Journal of Biological Chemistry 294 (34), 12846-12854, 2019 | 17 | 2019 |
IL-1β is an innate immune sensor of microbial proteolysis. Sci Immunol 1: eaah3539 CN LaRock, J Todd, DL LaRock, J Olson, AJ O’Donoghue, ... | 9 | 2016 |
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and … MJ Everett, DT Davies, S Leiris, N Sprynski, A Llanos, JM Castandet, ... ACS Infectious Diseases 9 (2), 270-282, 2023 | 8 | 2023 |
Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection AF Johnson, JS Sands, KM Trivedi, R Russell, DL LaRock, CN LaRock PLoS Pathogens 19 (4), e1011321, 2023 | 5 | 2023 |
Role of Inflammasome-independent Activation of IL-1β by the Pseudomonas aeruginosa Protease LasB J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, ... bioRxiv, 2020.05. 18.101303, 2020 | 2 | 2020 |
Assessing interleukin-1β activation during pyroptosis DL LaRock, CN LaRock Pyroptosis: Methods and Protocols, 163-169, 2023 | 1 | 2023 |
Pro-IL-18 secreted by keratinocytes detects the group A streptococcal protease SpeB AF Johnson, JS Sands, K Trivedi, R Russell, DL LaRock, CN LaRock bioRxiv, 2021.08. 22.457234, 2021 | 1 | 2021 |
Evaluation of Small Molecule Inhibitors of Pseudomonas Virulence factor LasB as Non‐Traditional Immunotherapeutics SR Chou, DL LaRock, J Sun, V Nizet, JK Bohannon, CN LaRock The FASEB Journal 36, 2022 | | 2022 |
Activation of the Salmonella enterica serovar Typhimurium translocated glycerophospholipid:cholesterol acyltransferase SseJ by the small GTPase RhoA DL LaRock University of Washington, 2012 | | 2012 |