BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges KL Chan, PS North, ID Hickson The EMBO journal 26 (14), 3397-3409, 2007 | 467 | 2007 |
The Bloom's syndrome gene product interacts with topoisomerase III L Wu, SL Davies, PS North, H Goulaouic, JF Riou, H Turley, KC Gatter, ... Journal of Biological Chemistry 275 (13), 9636-9644, 2000 | 365 | 2000 |
Role for BLM in replication-fork restart and suppression of origin firing after replicative stress SL Davies, PS North, ID Hickson Nature structural & molecular biology 14 (7), 677-679, 2007 | 269 | 2007 |
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest SL Davies, PS North, A Dart, ND Lakin, ID Hickson Molecular and cellular biology, 2004 | 248 | 2004 |
RUNX1 is a key target in t (4; 11) leukemias that contributes to gene activation through an AF4-MLL complex interaction AC Wilkinson, E Ballabio, H Geng, P North, M Tapia, J Kerry, D Biswas, ... Cell reports 3 (1), 116-127, 2013 | 161 | 2013 |
The rejoining of double-strand breaks in DNA by human cell extracts P North, A Ganesh, J Thacker Nucleic acids research 18 (21), 6205-6210, 1990 | 158 | 1990 |
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199 JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ... Cell reports 13 (12), 2715-2727, 2015 | 143 | 2015 |
A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats J Thacker, J Chalk, A Ganesh, P North Nucleic acids research 20 (23), 6183-6188, 1992 | 142 | 1992 |
Increased error-prone non homologous DNA end-joining–a proposed mechanism of chromosomal instability in Bloom's syndrome TJ Gaymes, PS North, N Brady, ID Hickson, GJ Mufti, FV Rassool Oncogene 21 (16), 2525-2533, 2002 | 138 | 2002 |
Phosphorylation of BLM, dissociation from topoisomerase IIIα, and colocalization with γ-H2AX after topoisomerase I-induced replication damage VA Rao, AM Fan, LH Meng, CF Doe, PS North, ID Hickson, Y Pommier Molecular and cellular biology 25 (20), 8925-8937, 2005 | 112 | 2005 |
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome AN Suhasini, NA Rawtani, Y Wu, JA Sommers, S Sharma, G Mosedale, ... The EMBO journal 30 (4), 692-705, 2011 | 99 | 2011 |
Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts A Ganesh, P North, J Thacker Mutation Research/Genetic Toxicology 299 (3-4), 251-259, 1993 | 73 | 1993 |
Role of the Bloom's syndrome helicase in maintenance of genome stability ID Hickson, SL Davies, JL Li, NC Levitt, P Mohaghegh, PS North, L Wu Biochemical Society Transactions 29 (2), 201-204, 2001 | 63 | 2001 |
Evidence for the involvement of DNA topoisomerase II in neutrophil-granulocyte differentiation. GE Francis, JJ Berney, PS North, Z Khan, EL Wilson, P Jacobs, M Ali Leukemia 1 (9), 653-659, 1987 | 32 | 1987 |
Topo IIIα and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents AW Hemphill, Y Akkari, AH Newell, RA Schultz, M Grompe, PS North, ... Cytogenetic and genome research 125 (3), 165-175, 2009 | 20 | 2009 |
Overexpression of the RIα subunit of protein kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-chloro-cyclic adenosine 3′, 5′-monophosphate in Chinese … PS North, SL Davies, F Ciardiello, V Damiano, C Bianco, S Pepe, ... Cancer research 54 (15), 4123-4128, 1994 | 14 | 1994 |
Cyclic AMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors. G Tortora, F Ciardiello, V Damiano, S Pepe, C Bianco, G di Isernia, ... Clinical cancer research: an official journal of the American Association …, 1995 | 11 | 1995 |
Mechanisms of resistance to ionising radiations: genetic and molecular studies on ataxia-telangiectasia and related radiation-sensitive mutants J Thacker, R Wilkinson, A Ganesh, P North DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells …, 1989 | 2 | 1989 |
Rejoining of DNA double-strand breaks by human cell-extracts P North, A Ganesh, J Thacker International Journal Of Radiation Biology 57 (6), 1254-1254, 1990 | 1 | 1990 |
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199 M Muschen, JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, ... | | 2015 |