Modulation of innate and adaptive immunity by cytomegaloviruses R Berry, GM Watson, S Jonjic, MA Degli-Esposti, J Rossjohn Nature reviews immunology 20 (2), 113-127, 2020 | 108 | 2020 |
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44 A Niehrs, WF Garcia-Beltran, PJ Norman, GM Watson, A Hölzemer, ... Nature Immunology 20 (9), 1129-1137, 2019 | 77 | 2019 |
Structural basis for CD96 immune receptor recognition of nectin-like protein-5, CD155 FA Deuss, GM Watson, Z Fu, J Rossjohn, R Berry Structure 27 (2), 219-228. e3, 2019 | 49 | 2019 |
Discovery, development, and cellular delivery of potent and selective bicyclic peptide inhibitors of Grb7 cancer target GM Watson, K Kulkarni, J Sang, X Ma, MJ Gunzburg, P Perlmutter, ... Journal of Medicinal Chemistry 60 (22), 9349-9359, 2017 | 29 | 2017 |
Cyclic peptides incorporating phosphotyrosine mimetics as potent and specific inhibitors of the Grb7 breast cancer target GM Watson, MJ Gunzburg, ND Ambaye, WAH Lucas, DA Traore, ... Journal of medicinal chemistry 58 (19), 7707-7718, 2015 | 25 | 2015 |
Shortened penetratin cell-penetrating peptide is insufficient for cytosolic delivery of a Grb7 targeting peptide GM Watson, K Kulkarni, R Brandt, MP Del Borgo, MI Aguilar, JA Wilce ACS omega 2 (2), 670-677, 2017 | 24 | 2017 |
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7 MJ Gunzburg, K Kulkarni, GM Watson, ND Ambaye, MP Del Borgo, ... Scientific Reports 6 (1), 27060, 2016 | 22 | 2016 |
A pocket guide on how to structure SARS-CoV-2 drugs and therapies DR Littler, BJ MacLachlan, GM Watson, JP Vivian, BS Gully Biochemical Society Transactions 48 (6), 2625-2641, 2020 | 14 | 2020 |
Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1 FA Deuss, GM Watson, KJ Goodall, I Leece, S Chatterjee, Z Fu, ... Journal of Biological Chemistry 294 (33), 12534-12546, 2019 | 14 | 2019 |
Direct interaction between calmodulin and the Grb7 RA-PH domain GM Watson, JA Wilce International Journal of Molecular Sciences 21 (4), 1336, 2020 | 8 | 2020 |
Evaluation of cyclic peptide inhibitors of the Grb7 breast Cancer target: small change in cargo results in large change in cellular activity J Sang, K Kulkarni, GM Watson, X Ma, DJ Craik, ST Henriques, AG Poth, ... Molecules 24 (20), 3739, 2019 | 8 | 2019 |
Insight into the selectivity of the G7-18NATE inhibitor peptide for the Grb7-SH2 domain target GM Watson, WAH Lucas, MJ Gunzburg, JA Wilce Frontiers in Molecular Biosciences 4, 64, 2017 | 8 | 2017 |
Preparation and cellular uptake of bicyclic‐peptide cargo clicked to cell penetrating peptides K Kulkarni, GM Watson, J Sang, JA Wilce Peptide Science 110 (3), e24037, 2018 | 5 | 2018 |
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1 MG Dans, C Boulet, GM Watson, W Nguyen, JM Dziekan, C Evelyn, ... Nature Communications 15 (1), 5219, 2024 | 3 | 2024 |
Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein W Nguyen, C Boulet, MG Dans, K Loi, KE Jarman, GM Watson, WH Tham, ... European Journal of Medicinal Chemistry 270, 116354, 2024 | 3 | 2024 |
Enhancing the bioactivity of bicyclic peptides targeted to Grb7-SH2 by restoring cell permeability NP Sturre, RN Colson, N Shah, GM Watson, X Yang, MCJ Wilce, JT Price, ... Biomedicines 10 (5), 1145, 2022 | 2 | 2022 |
Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids C Zimmermann, GM Watson, L Bauersfeld, R Berry, B Ciblis, H Lan, ... Proceedings of the National Academy of Sciences 121 (9), e2315985121, 2024 | 1 | 2024 |
Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1 MG Dans, C Boulet, GM Watson, W Nguyen, JM Dziekan, C Evelyn, ... bioRxiv, 2023.11. 02.565411, 2023 | 1 | 2023 |
Using Surface Plasmon Resonance to Study SH2 Domain–Peptide Interactions GM Watson, MJ Gunzburg, JA Wilce SH2 Domains: Functional Modules and Evolving Tools in Biology, 199-210, 2023 | | 2023 |
The natural cytotoxicity receptor NKp44 interacts with a subset of HLA-DP molecules A Niehrs, WF Garcia-Beltran, PJ Norman, GM Watson, A Hoelzemer, ... EUROPEAN JOURNAL OF IMMUNOLOGY 49, 20-21, 2019 | | 2019 |