CD4+ T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation K Rakhra, P Bachireddy, T Zabuawala, R Zeiser, L Xu, A Kopelman, ... Cancer cell 18 (5), 485-498, 2010 | 378 | 2010 |
CD47 blockade augmentation of trastuzumab antitumor efficacy dependent on antibody-dependent cellular phagocytosis LC Tsao, EJ Crosby, TN Trotter, P Agarwal, BJ Hwang, C Acharya, ... JCI insight 4 (24), 2019 | 94 | 2019 |
Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection EJ Crosby, MH Goldschmidt, EJ Wherry, P Scott PLoS pathogens 10 (2), e1003970, 2014 | 92 | 2014 |
Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors EJ Crosby, J Wei, XY Yang, G Lei, T Wang, CX Liu, P Agarwal, AJ Korman, ... Oncoimmunology 7 (5), e1421891, 2018 | 89 | 2018 |
The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment J Turpin, C Ling, EJ Crosby, ZC Hartman, AM Simond, LA Chodosh, ... Oncogene 35 (47), 6053-6064, 2016 | 78 | 2016 |
Vaccine-induced memory CD8+ T cells provide clinical benefit in HER2 expressing breast cancer: a mouse to human translational study EJ Crosby, W Gwin, K Blackwell, PK Marcom, S Chang, HT Maecker, ... Clinical Cancer Research 25 (9), 2725-2736, 2019 | 62 | 2019 |
Lymphocytic choriomeningitis virus expands a population of NKG2D+ CD8+ T cells that exacerbates disease in mice coinfected with Leishmania major EJ Crosby, M Clark, FO Novais, EJ Wherry, P Scott The Journal of Immunology 195 (7), 3301-3310, 2015 | 47 | 2015 |
Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti–PD-1 … ML Telli, H Nagata, I Wapnir, CR Acharya, K Zablotsky, BA Fox, ... Clinical Cancer Research 27 (9), 2481-2493, 2021 | 41 | 2021 |
Effector T cell egress via afferent lymph modulates local tissue inflammation D Gómez, MC Diehl, EJ Crosby, T Weinkopff, GF Debes The Journal of Immunology 195 (8), 3531-3536, 2015 | 40 | 2015 |
Stimulation of oncogene-specific tumor-infiltrating T cells through combined vaccine and αPD-1 enable sustained antitumor responses against established HER2 breast cancer EJ Crosby, CR Acharya, AF Haddad, CA Rabiola, G Lei, JP Wei, XY Yang, ... Clinical Cancer Research 26 (17), 4670-4681, 2020 | 38 | 2020 |
Combination of ultrasound-based mechanical disruption of tumor with immune checkpoint blockade modifies tumor microenvironment and augments systemic antitumor immunity S Abe, H Nagata, EJ Crosby, Y Inoue, K Kaneko, CX Liu, X Yang, T Wang, ... Journal for immunotherapy of cancer 10 (1), 2022 | 36 | 2022 |
Long-term survival of patients with stage III colon cancer treated with VRP-CEA (6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio EJ Crosby, AC Hobeika, D Niedzwiecki, C Rushing, D Hsu, P Berglund, ... Journal for immunotherapy of cancer 8 (2), 2020 | 36 | 2020 |
Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-induced … J Ren, WR Gwin, X Zhou, X Wang, H Huang, N Jiang, L Zhou, P Agarwal, ... Oncoimmunology 6 (4), e1264563, 2017 | 24 | 2017 |
Trastuzumab/pertuzumab combination therapy stimulates antitumor responses through complement-dependent cytotoxicity and phagocytosis LC Tsao, EJ Crosby, TN Trotter, J Wei, T Wang, X Yang, AN Summers, ... JCI insight 7 (6), 2022 | 22 | 2022 |
Immunosurveillance by Antiangiogenesis: Tumor Growth Arrest by T Cell–Derived Thrombospondin-1 KL Schadler, EJ Crosby, AY Zhou, DH Bhang, L Braunstein, KH Baek, ... Cancer research 74 (8), 2171-2181, 2014 | 20 | 2014 |
Clinical trials of self-replicating RNA-based cancer vaccines MA Morse, EJ Crosby, J Force, T Osada, AC Hobeika, ZC Hartman, ... Cancer Gene Therapy 30 (6), 803-811, 2023 | 19 | 2023 |
Cancer vaccine strategies using self-replicating RNA viral platforms GP Dailey, EJ Crosby, ZC Hartman Cancer Gene Therapy 30 (6), 794-802, 2023 | 14 | 2023 |
HER2 isoforms uniquely program intratumor heterogeneity and predetermine breast cancer trajectories during the occult tumorigenic phase JD Ginzel, CR Acharya, V Lubkov, H Mori, PG Boone, LK Rochelle, ... Molecular Cancer Research 19 (10), 1699-1711, 2021 | 12 | 2021 |
Delayed rejection of MHC class II-disparate skin allografts in mice treated with farnesyltransferase inhibitors. FKA Gaylo AE, Laux KS, Batzel EJ, Berg ME Transpl Immunol 20 (3), 163-70, 2009 | 7 | 2009 |
HSP90-specific nIR probe identifies aggressive prostate cancers: translation from preclinical models to a human phase I study T Osada, EJ Crosby, K Kaneko, JC Snyder, JD Ginzel, CR Acharya, ... Molecular cancer therapeutics 21 (1), 217-226, 2022 | 5 | 2022 |