Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ... Molecular cell 63 (1), 167-178, 2016 | 522 | 2016 |
Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin Elife 4, e08007, 2015 | 189 | 2015 |
DNA Topoisomerase I differentially modulates R-loops across the human genome SG Manzo, SR Hartono, LA Sanz, J Marinello, S De Biasi, A Cossarizza, ... Genome biology 19, 1-18, 2018 | 155 | 2018 |
The affinity of the S9. 6 antibody for double-stranded RNAs impacts the accurate mapping of R-loops in fission yeast SR Hartono, A Malapert, P Legros, P Bernard, F Chédin, V Vanoosthuyse Journal of molecular biology 430 (3), 272-284, 2018 | 152 | 2018 |
Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA: RNA hybrids S Sagie, S Toubiana, SR Hartono, H Katzir, A Tzur-Gilat, S Havazelet, ... Nature communications 8 (1), 14015, 2017 | 122 | 2017 |
Interplay between DNA sequence and negative superhelicity drives R-loop structures R Stolz, S Sulthana, SR Hartono, M Malig, CJ Benham, F Chedin Proceedings of the National Academy of Sciences 116 (13), 6260-6269, 2019 | 119 | 2019 |
Recognition of RNA by the S9. 6 antibody creates pervasive artifacts when imaging RNA: DNA hybrids JA Smolka, LA Sanz, SR Hartono, F Chédin Journal of Cell Biology 220 (6), e202004079, 2021 | 105 | 2021 |
Best practices for the visualization, mapping, and manipulation of R‐loops F Chédin, SR Hartono, LA Sanz, V Vanoosthuyse The EMBO journal 40 (4), e106394, 2021 | 75 | 2021 |
Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation CA Gordon, SR Hartono, F Chédin PloS one 8 (7), e69486, 2013 | 70 | 2013 |
Sequencing the transcriptome of milk production: milk trumps mammary tissue DG Lemay, RC Hovey, SR Hartono, K Hinde, JT Smilowitz, F Ventimiglia, ... BMC genomics 14, 1-17, 2013 | 68 | 2013 |
Ultra-deep coverage single-molecule R-loop footprinting reveals principles of R-loop formation M Malig, SR Hartono, JM Giafaglione, LA Sanz, F Chedin Journal of molecular biology 432 (7), 2271-2288, 2020 | 67 | 2020 |
GC skew is a conserved property of unmethylated CpG island promoters across vertebrates SR Hartono, IF Korf, F Chédin Nucleic acids research 43 (20), 9729-9741, 2015 | 67 | 2015 |
CARM1 inhibition enables immunotherapy of resistant tumors by dual action on tumor cells and T cells S Kumar, Z Zeng, A Bagati, RE Tay, LA Sanz, SR Hartono, Y Ito, ... Cancer discovery 11 (8), 2050-2071, 2021 | 61 | 2021 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation P Richard, S Feng, YL Tsai, W Li, P Rinchetti, U Muhith, J Irizarry-Cole, ... Autophagy 17 (8), 1889-1906, 2021 | 46 | 2021 |
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma V Giuliani, MA Miller, CY Liu, SR Hartono, CA Class, CA Bristow, E Suzuki, ... Nature communications 12 (1), 4626, 2021 | 44 | 2021 |
SF3B1-targeted splicing inhibition triggers global alterations in transcriptional dynamics and R-loop metabolism D Castillo-Guzman, SR Hartono, LA Sanz, F Chédin BioRxiv, 2020.06. 08.130583, 2020 | 20 | 2020 |
Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length SS Shah, S Hartono, A Piazza, V Som, W Wright, F Chédin, WD Heyer Elife 9, e59112, 2020 | 17 | 2020 |
Quality-controlled R-loop meta-analysis reveals the characteristics of R-loop consensus regions HE Miller, D Montemayor, J Abdul, A Vines, SA Levy, SR Hartono, ... Nucleic acids research 50 (13), 7260-7286, 2022 | 14 | 2022 |
Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination H Zhao, SR Hartono, KMF de Vera, Z Yu, K Satchi, T Zhao, R Sciammas, ... Elife 11, e78917, 2022 | 10 | 2022 |
Exploration and analysis of R-loop mapping data with RLBase HE Miller, D Montemayor, J Li, SA Levy, R Pawar, S Hartono, K Sharma, ... Nucleic acids research 51 (D1), D1129-D1137, 2023 | 8 | 2023 |