| Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation BJ Fraser, S Beldar, A Seitova, A Hutchinson, D Mannar, Y Li, D Kwon, ... Nature chemical biology 18 (9), 963-971, 2022 | 137 | 2022 |
| Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response MM Szewczyk, Y Ishikawa, S Organ, N Sakai, F Li, L Halabelian, S Ackloo, ... Nature communications 11 (1), 2396, 2020 | 92 | 2020 |
| The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates ME Jakobsson, JM Małecki, L Halabelian, BS Nilges, R Pinto, ... Nature Communications 9 (1), 3411, 2018 | 90 | 2018 |
| HMCES functions in the alternative end-joining pathway of the DNA DSB repair during class switch recombination in B cells V Shukla, L Halabelian, S Balagere, D Samaniego-Castruita, DE Feldman, ... Molecular cell 77 (2), 384-394. e4, 2020 | 62 | 2020 |
| Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition L Halabelian, M Ravichandran, Y Li, H Zeng, A Rao, L Aravind, ... Nature structural & molecular biology 26 (7), 607-612, 2019 | 59 | 2019 |
| Identification of lysine isobutyrylation as a new histone modification mark Z Zhu, Z Han, L Halabelian, X Yang, J Ding, N Zhang, L Ngo, J Song, ... Nucleic Acids Research 49 (1), 177-189, 2021 | 48 | 2021 |
| Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex D Ivanochko, L Halabelian, E Henderson, P Savitsky, H Jain, E Marcon, ... Nucleic acids research 47 (3), 1225-1238, 2019 | 43 | 2019 |
| Discovery of a first-in-class protein arginine methyltransferase 6 (PRMT6) covalent inhibitor Y Shen, F Li, MM Szewczyk, L Halabelian, KS Park, I Chau, A Dong, ... Journal of medicinal chemistry 63 (10), 5477-5487, 2020 | 37 | 2020 |
| Discovery of a chemical probe for PRDM9 A Allali-Hassani, MM Szewczyk, D Ivanochko, SL Organ, J Bok, JSY Ho, ... Nature communications 10 (1), 5759, 2019 | 37 | 2019 |
| Discovery of nanomolar DCAF1 small molecule ligands ASM Li, S Kimani, B Wilson, M Noureldin, H González-Álvarez, A Mamai, ... Journal of Medicinal Chemistry 66 (7), 5041-5060, 2023 | 33 | 2023 |
| Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin L Halabelian, S Ricagno, S Giorgetti, C Santambrogio, A Barbiroli, ... Journal of Biological Chemistry 289 (6), 3318-3327, 2014 | 32 | 2014 |
| Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2 K Delaney, M Tan, Z Zhu, J Gao, L Dai, S Kim, J Ding, M He, L Halabelian, ... Cell Discovery 7 (1), 122, 2021 | 29 | 2021 |
| A first-in-class, highly selective and cell-active allosteric inhibitor of protein arginine methyltransferase 6 Y Shen, F Li, MM Szewczyk, L Halabelian, I Chau, MS Eram, C Dela Sena, ... Journal of medicinal chemistry 64 (7), 3697-3706, 2021 | 23 | 2021 |
| The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface J Guegueniat, L Halabelian, H Zeng, A Dong, Y Li, H Wu, CH Arrowsmith, ... Nucleic acids research 49 (20), 11810-11822, 2021 | 22 | 2021 |
| Structure, activity and inhibition of human TMPRSS2, a protease implicated in SARS-CoV-2 activation BJ Fraser, S Beldar, A Seitova, A Hutchinson, D Mannar, Y Li, D Kwon, ... BioRxiv, 2021.06. 23.449282, 2021 | 21 | 2021 |
| Structure and function of protein arginine methyltransferase PRMT7 L Halabelian, D Barsyte-Lovejoy Life 11 (8), 768, 2021 | 19 | 2021 |
| Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid L Mélin, S Abdullayev, A Fnaiche, V Vu, N González Suárez, H Zeng, ... ChemMedChem 16 (19), 2982-3002, 2021 | 18 | 2021 |
| Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells K Sugata, Y Matsunaga, Y Yamashita, M Nakatsugawa, T Guo, ... Nature Biotechnology 39 (8), 958-967, 2021 | 18 | 2021 |
| A covalent homodimer probing early oligomers along amyloid aggregation L Halabelian, A Relini, A Barbiroli, A Penco, M Bolognesi, S Ricagno Scientific reports 5 (1), 14651, 2015 | 18 | 2015 |
| Wild type beta-2 microglobulin and DE loop mutants display a common fibrillar architecture A Natalello, A Relini, A Penco, L Halabelian, M Bolognesi, SM Doglia, ... PLoS One 10 (3), e0122449, 2015 | 15 | 2015 |
