The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 751 | 2019 |
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 459 | 2021 |
Structure, function and pathophysiology of protease activated receptors MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ... Pharmacology & therapeutics 130 (3), 248-282, 2011 | 459 | 2011 |
Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more R Ramachandran, MD Hollenberg British journal of pharmacology 153 (S1), S263-S282, 2008 | 421 | 2008 |
Targeting proteinase-activated receptors: therapeutic potential and challenges R Ramachandran, F Noorbakhsh, K DeFea, MD Hollenberg Nature reviews Drug discovery 11 (1), 69-86, 2012 | 377 | 2012 |
The concise guide to pharmacology 2017/18: overview SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ... British journal of pharmacology 174, S1-S16, 2017 | 310 | 2017 |
Biased signalling and proteinase‐activated receptors (PAR s): targeting inflammatory disease MD Hollenberg, K Mihara, D Polley, JY Suen, A Han, DP Fairlie, ... British journal of pharmacology 171 (5), 1180-1194, 2014 | 203 | 2014 |
Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2) R Ramachandran, K Mihara, H Chung, B Renaux, CS Lau, DA Muruve, ... Journal of Biological Chemistry 286 (28), 24638-24648, 2011 | 188 | 2011 |
TRPM8 activation attenuates inflammatory responses in mouse models of colitis R Ramachandran, E Hyun, L Zhao, TK Lapointe, K Chapman, CL Hirota, ... Proceedings of the National Academy of Sciences 110 (18), 7476-7481, 2013 | 187 | 2013 |
The concise guide to PHARMACOLOGY 2013/14: overview SPH Alexander, HE Benson, E Faccenda, AJ Pawson, JL Sharman, ... British journal of pharmacology 170 (8), 1449-1458, 2013 | 183 | 2013 |
Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1) K Mihara, R Ramachandran, B Renaux, M Saifeddine, MD Hollenberg Journal of Biological Chemistry 288 (46), 32979-32990, 2013 | 132 | 2013 |
Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways R Ramachandran, K Mihara, M Mathur, MD Rochdi, M Bouvier, K DeFea, ... Molecular pharmacology 76 (4), 791-801, 2009 | 125 | 2009 |
The active Zot domain (aa 288–293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight … SE Goldblum, U Rai, A Tripathi, M Thakar, L De Leo, N Di Toro, T Not, ... The FASEB journal 25 (1), 144, 2011 | 119 | 2011 |
MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase‐6 regulates astrocyte survival F Noorbakhsh, R Ramachandran, N Barsby, KK Ellestad, A LeBlanc, ... The FASEB Journal 24 (6), 1799-1812, 2010 | 105 | 2010 |
Proteinase-activated receptor-2 transactivation of epidermal growth factor receptor and transforming growth factor-β receptor signaling pathways contributes to renal fibrosis H Chung, R Ramachandran, MD Hollenberg, DA Muruve Journal of Biological Chemistry 288 (52), 37319-37331, 2013 | 98 | 2013 |
Thrombin-mediated direct activation of proteinase-activated receptor-2: another target for thrombin signaling K Mihara, R Ramachandran, M Saifeddine, KK Hansen, B Renaux, ... Molecular pharmacology 89 (5), 606-614, 2016 | 94 | 2016 |
Proteinases, their extracellular targets, and inflammatory signaling R Ramachandran, C Altier, K Oikonomopoulou, MD Hollenberg Pharmacological reviews 68 (4), 1110-1142, 2016 | 84 | 2016 |
Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer MD Hollenberg, K Oikonomopoulou, KK Hansen, M Saifeddine, ... Walter de Gruyter 389 (6), 643-651, 2008 | 83 | 2008 |
Activities enjoyed by patients with dementia together with their spouses and psychological morbidity in carers R Searson, AM Hendry, R Ramachandran, A Burns, N Purandare Aging and Mental Health 12 (2), 276-282, 2008 | 72 | 2008 |
Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts LR Sadofsky, R Ramachandran, C Crow, M Cowen, SJ Compton, ... Experimental lung research 38 (2), 75-81, 2012 | 67 | 2012 |