Virus-induced senescence is a driver and therapeutic target in COVID-19 S Lee, Y Yu, J Trimpert, F Benthani, M Mairhofer, P Richter-Pechanska, ... Nature 599 (7884), 283-289, 2021 | 256 | 2021 |
A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations F Bertoglio, V Fühner, M Ruschig, PA Heine, L Abassi, T Klünemann, ... Cell reports 36 (4), 2021 | 80 | 2021 |
Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding J Trimpert, K Dietert, TC Firsching, N Ebert, TTN Thao, D Vladimirova, ... Cell reports 36 (5), 2021 | 52 | 2021 |
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters G Nouailles, JM Adler, P Pennitz, S Peidli, LG Teixeira Alves, ... Nature Microbiology 8 (5), 860-874, 2023 | 44 | 2023 |
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants S Rothenberger, DL Hurdiss, M Walser, F Malvezzi, J Mayor, S Ryter, ... Nature biotechnology 40 (12), 1845-1854, 2022 | 43 | 2022 |
Inhibition of SARS-CoV-2 replication by a small interfering RNA targeting the leader sequence B Tolksdorf, C Nie, D Niemeyer, V Röhrs, J Berg, D Lauster, JM Adler, ... Viruses 13 (10), 2030, 2021 | 33 | 2021 |
Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B. 1.1. 7 (Alpha) and B. 1.351 (Beta) J Trimpert, JM Adler, K Eschke, A Abdelgawad, TC Firsching, N Ebert, ... Science Advances 7 (49), eabk0172, 2021 | 32 | 2021 |
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics E Wyler, JM Adler, K Eschke, GT Alves, S Peidli, F Pott, J Kazmierski, ... Molecular Therapy 30 (5), 1952-1965, 2022 | 29 | 2022 |
The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in … IL Shytaj, M Fares, L Gallucci, B Lucic, MM Tolba, L Zimmermann, ... Mbio 13 (2), e03705-21, 2022 | 29 | 2022 |
A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients by phage display is binding to the ACE2-RBD interface and is tolerant to most known recently emerging RBD … F Bertoglio, V Fühner, M Ruschig, PA Heine, L Abasi, T Klünemann, ... BioRxiv, 2020.12. 03.409318, 2020 | 17 | 2020 |
Functionalized Fullerene for Inhibition of SARS‐CoV‐2 Variants TM Page, C Nie, L Neander, TL Povolotsky, AK Sahoo, P Nickl, JM Adler, ... small 19 (15), 2206154, 2023 | 13 | 2023 |
Prevalence of anti‐severe acute respiratory syndrome coronavirus 2 antibodies in cats in Germany and other European countries in the early phase of the coronavirus disease‐19 … JM Adler, C Weber, K Wernike, A Michelitsch, K Friedrich, J Trimpert, ... Zoonoses and Public Health 69 (5), 439-450, 2022 | 13 | 2022 |
Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants S Rothenberger, DL Hurdiss, M Walser, F Malvezzi, J Mayor, S Ryter, ... bioRxiv, 2021.02. 03.429164, 2021 | 12 | 2021 |
Multi-specific DARPin (R) therapeutics demonstrate very high potency against mutated SARS-CoV-2 variants in vitro S Rothenberger, DL Hurdiss, M Walser, F Malvezzi, J Mayor, S Ryter, ... | 11 | 2021 |
An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission JM Adler, R Martin Vidal, C Langner, D Vladimirova, A Abdelgawad, ... Nature Communications 15 (1), 995, 2024 | 10 | 2024 |
A non-transmissible live attenuated SARS-CoV-2 vaccine JM Adler, RM Vidal, A Voß, S Kunder, M Nascimento, A Abdelgawad, ... Molecular Therapy 31 (8), 2391-2407, 2023 | 8 | 2023 |
Deciphering the role of humoral and cellular immune responses in different COVID-19 vaccines—a comparison of vaccine candidate genes in Roborovski dwarf hamsters J Trimpert, S Herwig, J Stein, D Vladimirova, JM Adler, A Abdelgawad, ... Viruses 13 (11), 2290, 2021 | 8 | 2021 |
Antigenic cartography using variant-specific hamster sera reveals substantial antigenic variation among Omicron subvariants B Mühlemann, J Trimpert, F Walper, ML Schmidt, J Jansen, S Schroeder, ... Proceedings of the National Academy of Sciences 121 (32), e2310917121, 2024 | 5 | 2024 |
In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and … J Emanuel, J Papies, C Galander, JM Adler, N Heinemann, K Eschke, ... Frontiers in pharmacology 14, 1214351, 2023 | 3 | 2023 |
Neural Network-Assisted Humanization of COVID-19 Hamster scRNAseq Data Reveals Matching Severity States in Human Disease VD Friedrich, P Pennitz, E Wyler, JM Adler, D Postmus, LGT Alves, ... bioRxiv, 2024.01. 11.574849, 2024 | 2 | 2024 |