| Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 123 | 2019 |
| Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... Cell chemical biology 29 (2), 191-201. e8, 2022 | 57 | 2022 |
| Mechanism of feedback allosteric inhibition of ATP phosphoribosyltransferase S Pedreño, JP Pisco, G Larrouy-Maumus, G Kelly, LPS de Carvalho Biochemistry 51 (40), 8027-8038, 2012 | 41 | 2012 |
| Hybrid mass spectrometry approaches to determine how L-histidine feedback regulates the enzyzme MtATP-phosphoribosyltransferase KJ Pacholarz, RJ Burnley, TA Jowitt, V Ordsmith, JP Pisco, M Porrini, ... Structure 25 (5), 730-738. e4, 2017 | 27 | 2017 |
| Uncoupling conformational states from activity in an allosteric enzyme JP Pisco, C De Chiara, KJ Pacholarz, A Garza-Garcia, RW Ogrodowicz, ... Nature communications 8 (1), 203, 2017 | 24 | 2017 |
| Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention. Cell Chem Biol 29: 191-201. e8 RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... | 6 | 2022 |
| Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors AJ Wilkinson, N Ooi, J Finlayson, VE Lee, D Lyth, KS Maskew, R Newman, ... Bioorganic & Medicinal Chemistry Letters 90, 129331, 2023 | 1 | 2023 |
| Identification of the Plasmodium falciparum acetyl-CoA synthetase as an emerging antiplasmodial drug target RL Summers, M Vanaerschot, JM Murithi, CF Pasaje, MR Luth, ... American Journal of Tropical Medicine and Hygiene 101 (5_Suppl), 476-477, 2019 | 1 | 2019 |
| Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis LP de Carvalho, D Hunt, J Pisco, A Rodgers, C de Chiara, A Zaveri, ... | | 2024 |
| INHIBITION OF THE PLASMODIUM FALCIPARUM ACETYL-COA SYNTHETASE BY MULTIPLE CHEMOTYPES DISRUPTS PROTEIN ACETYLATION AND EPIGENETIC REGULATION IN BLOOD STAGE PARASITES R Summers, C Pasaje, J Pisco, M Vanaerschot, J Murithi, M Luth, J Munro, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 70-70, 2021 | | 2021 |
| Full wwPDB X-ray Structure Validation Report i NE Clark, SC Garman | | |
