Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ... Molecular pharmaceutics 14 (12), 4281-4294, 2017 | 132 | 2017 |
Exploring gastrointestinal variables affecting drug and formulation behavior: methodologies, challenges and opportunities B Hens, M Corsetti, R Spiller, L Marciani, T Vanuytsel, J Tack, A Talattof, ... International Journal of Pharmaceutics 519 (1-2), 79-97, 2017 | 115 | 2017 |
Project aria: A new tool for egocentric multi-modal ai research J Engel, K Somasundaram, M Goesele, A Sun, A Gamino, A Turner, ... arXiv preprint arXiv:2308.13561, 2023 | 59 | 2023 |
Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’project B Hens, PD Sinko, N Job, M Dean, J Al-Gousous, N Salehi, RM Ziff, ... International journal of pharmaceutics 548 (1), 120-127, 2018 | 51 | 2018 |
Gastrointestinal motility variation and implications for plasma level variation: oral drug products A Talattof, JC Price, GL Amidon Molecular pharmaceutics 13 (2), 557-567, 2016 | 49 | 2016 |
Using physiologically based pharmacokinetic (PBPK) modeling to evaluate the impact of pharmaceutical excipients on oral drug absorption: sensitivity analyses ECY Chow, A Talattof, E Tsakalozou, J Fan, L Zhao, X Zhang The AAPS journal 18, 1500-1511, 2016 | 40 | 2016 |
Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ... European Journal of Pharmaceutics and Biopharmaceutics 129, 162-174, 2018 | 32 | 2018 |
Linking the gastrointestinal behavior of ibuprofen with the systemic exposure between and within humans—part 1: fasted state conditions M Bermejo, P Paixão, B Hens, Y Tsume, MJ Koenigsknecht, JR Baker, ... Molecular pharmaceutics 15 (12), 5454-5467, 2018 | 27 | 2018 |
Measuring the impact of gastrointestinal variables on the systemic outcome of two suspensions of posaconazole by a PBPK model B Hens, A Talattof, P Paixão, M Bermejo, Y Tsume, R Löbenberg, ... The AAPS Journal 20, 1-14, 2018 | 24 | 2018 |
Massive Bioaccumulation and Self‐Assembly of Phenazine Compounds in Live Cells KA Min, WG Rajeswaran, R Oldenbourg, G Harris, RK Keswani, M Chiang, ... Advanced Science 2 (8), 1500025, 2015 | 18 | 2015 |
Pulse packet stochastic model for gastric emptying in the fasted state: a physiological approach A Talattof, GL Amidon Molecular Pharmaceutics 15 (6), 2107-2115, 2018 | 17 | 2018 |
Modeling temperature-dependent dermal absorption and clearance for transdermal and topical drug applications TD LaCount, Q Zhang, J Hao, P Ghosh, SG Raney, A Talattof, GB Kasting, ... The AAPS journal 22, 1-13, 2020 | 16 | 2020 |
Linking the gastrointestinal behavior of ibuprofen with the systemic exposure between and within humans—part 2: fed state P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ... Molecular pharmaceutics 15 (12), 5468-5478, 2018 | 14 | 2018 |
Physiologically based pharmacokinetic and absorption modeling for osmotic pump products Z Ni, A Talattof, J Fan, E Tsakalozou, S Sharan, D Sun, H Wen, L Zhao, ... The AAPS Journal 19, 1045-1053, 2017 | 14 | 2017 |
The extracellular microenvironment explains variations in passive drug transport across different airway epithelial cell types KA Min, A Talattof, Y Tsume, KA Stringer, J Yu, DH Lim, GR Rosania Pharmaceutical research 30, 2118-2132, 2013 | 12 | 2013 |
Evaluation of Heat Effects on Transdermal Nicotine Delivery In Vitro and In Silico Using Heat-Enhanced Transport Model Analysis TD La Count, Q Zhang, M Murawsky, J Hao, P Ghosh, K Dave, SG Raney, ... The AAPS journal 22, 1-14, 2020 | 8 | 2020 |
Summary of the In Vivo Predictive Dissolution (iPD): Oral Drug Delivery (ODD) Conference 2018 B Hens, J Al-Gousous, K Wang, N Salehi, RM Ziff, Y Tsume, M Bermejo, ... Dissolution Technologies 25 (2), 2018 | 1 | 2018 |
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State P Paixao, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ... Molecular Pharmaceutics 15 (12), 5468-5478, 2018 | | 2018 |
Dynamic Change in pH by Low Buffer Capacity of Gastrointestinal Fluids Along The Human Gastrointestinal Tract: Implications For In Vivo Dissolution and Absorption of Ionizable … B Hens, Y Tsume, M Bermejo, P Paixão, M Koenigsknecht, J Baker R, ... Annual AAPS Meeting, Date: 2017/11/12-2017/11/15, Location: San Diego, CA, 2017 | | 2017 |
Mechanistic Analysis and Quantification of Gastrointestinal Motility: Physiological Variability and Plasma Level Implications. A Talattof | | 2015 |