Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 593 | 2020 |
Rapid determination of quaternary protein structures in complex biological samples S Hauri*, H Khakzad*, L Happonen, J Teleman, J Malmström, ... Nature communications 10 (1), 1-10, 2019 | 55 | 2019 |
Spike-dependent opsonization indicates both dose-dependent inhibition of phagocytosis and that non-neutralizing antibodies can confer protection to SARS-CoV-2 W Bahnan, S Wrighton, M Sundwall, A Bläckberg, O Larsson, U Höglund, ... Frontiers in immunology 12, 808932, 2022 | 54 | 2022 |
A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodies L Happonen, S Hauri, G Svensson Birkedal, C Karlsson, T de Neergaard, ... Nature communications 10 (1), 2727, 2019 | 49 | 2019 |
Better together: Elements of successful scientific software development in a distributed collaborative community J Koehler Leman, BD Weitzner, PD Renfrew, SM Lewis, R Moretti, ... PLoS computational biology 16 (5), e1007507, 2020 | 34 | 2020 |
De novo protein design by inversion of the AlphaFold structure prediction network CA Goverde, B Wolf, H Khakzad, S Rosset, BE Correia Protein Science 32 (6), e4653, 2023 | 30 | 2023 |
Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology H Khakzad, L Happonen, Y Karami, S Chowdhury, GE Bergdahl, M Nilges, ... PLoS Computational Biology 17 (1), e1008169, 2021 | 17 | 2021 |
A new age in protein design empowered by deep learning H Khakzad, I Igashov, A Schneuing, C Goverde, M Bronstein, B Correia Cell Systems 14 (11), 925-939, 2023 | 16 | 2023 |
A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function W Bahnan, L Happonen, H Khakzad, V Kumra Ahnlide, T de Neergaard, ... EMBO Molecular Medicine 15 (2), e16208, 2023 | 13* | 2023 |
Streptococcus pyogenes forms serotype-and local environment-dependent interspecies protein complexes S Chowdhury, H Khakzad, GE Bergdahl, R Lood, S Ekstrom, D Linke, ... Msystems 6 (5), 10.1128/msystems. 00271-21, 2021 | 12 | 2021 |
Structural proteomics, electron cryo-microscopy and structural modeling approaches in bacteria–human protein interactions S Chowdhury, L Happonen, H Khakzad, L Malmström, J Malmström Medical microbiology and immunology 209 (3), 265-275, 2020 | 12 | 2020 |
Protein structure prediction using bio-inspired algorithm: A review Y Karami, H Khakzad, H Shirazi, S Arab The 16th CSI international symposium on artificial intelligence and signal …, 2012 | 10 | 2012 |
In vivo cross-linking MS of the complement system MAC assembled on live Gram-positive bacteria H Khakzad, L Happonen, G Tran Van Nhieu, J Malmström, L Malmström Frontiers in Genetics 11, 612475, 2021 | 9 | 2021 |
PDB2Graph: A toolbox for identifying critical amino acids map in proteins based on graph theory N Niknam, H Khakzad, SS Arab, H Naderi-Manesh Computers in biology and medicine 72, 151-159, 2016 | 9 | 2016 |
Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint C Valencia-Gallardo, DI Aguilar-Salvador, H Khakzad, B Cocom-Chan, ... Cell Reports 42 (4), 2023 | 8* | 2023 |
Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics C Gueto-Tettay, D Tang, L Happonen, M Heusel, H Khakzad, ... PLoS Computational Biology 19 (1), e1010457, 2023 | 6 | 2023 |
The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms M Hasan*, H Khakzad*, L Happonen, A Sundin, J Unge, U Mueller, ... Chemical science 12 (5), 1869-1885, 2021 | 6 | 2021 |
Accelerating protein structure prediction using particle swarm optimization on GPU H Khakzad, Y Karami, SS Arab Biorxiv, 022434, 2015 | 6 | 2015 |
Invasive streptococcal infection can lead to the generation of cross-strain opsonic antibodies T de Neergaard, A Bläckberg, H Ivarsson, S Thomasson, ... Microbiology spectrum 10 (6), e02486-22, 2022 | 3 | 2022 |
Greedy de novo motif discovery to construct motif repositories for bacterial proteomes H Khakzad, J Malmström, L Malmström BMC bioinformatics 20, 1-10, 2019 | 3 | 2019 |