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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma MA Pule, B Savoldo, GD Myers, C Rossig, HV Russell, G Dotti, MH Huls, ... Nature medicine 14 (11), 1264-1270, 2008 | 1375 | 2008 |
Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma CU Louis, B Savoldo, G Dotti, M Pule, E Yvon, GD Myers, C Rossig, ... Blood, The Journal of the American Society of Hematology 118 (23), 6050-6056, 2011 | 1327 | 2011 |
CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients B Savoldo, CA Ramos, E Liu, MP Mims, MJ Keating, G Carrum, ... The Journal of clinical investigation 121 (5), 1822-1826, 2011 | 1245 | 2011 |
Human epidermal growth factor receptor 2 (HER2)–specific chimeric antigen receptor–modified T cells for the immunotherapy of HER2-positive sarcoma N Ahmed, VS Brawley, M Hegde, C Robertson, A Ghazi, C Gerken, E Liu, ... Journal of clinical oncology 33 (15), 1688-1696, 2015 | 1038 | 2015 |
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients HE Heslop, KS Slobod, MA Pule, GA Hale, A Rousseau, CA Smith, ... Blood, The Journal of the American Society of Hematology 115 (5), 925-935, 2010 | 915 | 2010 |
Closely related T-memory stem cells correlate with in vivo expansion of CAR. CD19-T cells and are preserved by IL-7 and IL-15 Y Xu, M Zhang, CA Ramos, A Durett, E Liu, O Dakhova, H Liu, ... Blood, The Journal of the American Society of Hematology 123 (24), 3750-3759, 2014 | 779 | 2014 |
HER2-specific chimeric antigen receptor–modified virus-specific T cells for progressive glioblastoma: a phase 1 dose-escalation trial N Ahmed, V Brawley, M Hegde, K Bielamowicz, M Kalra, D Landi, ... JAMA oncology 3 (8), 1094-1101, 2017 | 752 | 2017 |
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes I Caruana, B Savoldo, V Hoyos, G Weber, H Liu, ES Kim, MM Ittmann, ... Nature medicine 21 (5), 524-529, 2015 | 730 | 2015 |
Perineural invasion is an independent predictor of outcome in colorectal cancer C Liebig, G Ayala, J Wilks, G Verstovsek, H Liu, N Agarwal, DH Berger, ... Journal of clinical oncology 27 (31), 5131-5137, 2009 | 614 | 2009 |
Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins CM Bollard, S Gottschalk, V Torrano, O Diouf, S Ku, Y Hazrat, G Carrum, ... Journal of Clinical Oncology 32 (8), 798-808, 2014 | 540 | 2014 |
CAR T cells administered in combination with lymphodepletion and PD-1 inhibition to patients with neuroblastoma A Heczey, CU Louis, B Savoldo, O Dakhova, A Durett, B Grilley, H Liu, ... Molecular therapy 25 (9), 2214-2224, 2017 | 485 | 2017 |
TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype F Zhang, H Wang, X Wang, G Jiang, H Liu, G Zhang, H Wang, R Fang, ... Oncotarget 7 (32), 52294, 2016 | 481 | 2016 |
Off-the-shelf virus-specific T cells to treat BK virus, human herpesvirus 6, cytomegalovirus, Epstein-Barr virus, and adenovirus infections after allogeneic hematopoietic stem … I Tzannou, A Papadopoulou, S Naik, K Leung, CA Martinez, CA Ramos, ... Journal of Clinical Oncology 35 (31), 3547-3557, 2017 | 441 | 2017 |
Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT A Papadopoulou, U Gerdemann, UL Katari, I Tzannou, H Liu, C Martinez, ... Science translational medicine 6 (242), 242ra83-242ra83, 2014 | 431 | 2014 |
Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma M Hegde, A Corder, KKH Chow, M Mukherjee, A Ashoori, Y Kew, ... Molecular Therapy 21 (11), 2087-2101, 2013 | 406 | 2013 |
Clinical and immunological responses after CD30-specific chimeric antigen receptor–redirected lymphocytes CA Ramos, B Ballard, H Zhang, O Dakhova, AP Gee, Z Mei, M Bilgi, ... The Journal of clinical investigation 127 (9), 3462-3471, 2017 | 385 | 2017 |
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell … AM Leen, A Christin, GD Myers, H Liu, CR Cruz, PJ Hanley, ... Blood, The Journal of the American Society of Hematology 114 (19), 4283-4292, 2009 | 375 | 2009 |
Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma S Kakarla, KKH Chow, M Mata, DR Shaffer, XT Song, MF Wu, H Liu, ... Molecular Therapy 21 (8), 1611-1620, 2013 | 346 | 2013 |
Armed oncolytic virus enhances immune functions of chimeric antigen receptor–modified T cells in solid tumors N Nishio, I Diaconu, H Liu, V Cerullo, I Caruana, V Hoyos, ... Cancer research 74 (18), 5195-5205, 2014 | 332 | 2014 |