| New arylthioindoles: Potent Inhibitors of tubulin polymerization. 2. Structure− activity relationships and molecular modeling studies G De Martino, MC Edler, G La Regina, A Coluccia, MC Barbera, D Barrow, ... Journal of medicinal chemistry 49 (3), 947-954, 2006 | 437 | 2006 |
| Arylthioindoles, potent inhibitors of tubulin polymerization G De Martino, G La Regina, A Coluccia, MC Edler, MC Barbera, ... Journal of medicinal chemistry 47 (25), 6120-6123, 2004 | 330 | 2004 |
| New Arylthioindoles Inhibitors of Tubulin Polymerization 3. Biological evaluation, structure-activity relationships and molecular modeling studies G La Regina, MC Edler, A Brancale, S Kandil, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 50 (12), 2865-2874, 2007 | 226 | 2007 |
| Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies R Silvestri, G De Martino, G La Regina, M Artico, S Massa, L Vargiu, ... Journal of medicinal chemistry 46 (12), 2482-2493, 2003 | 211 | 2003 |
| Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide G La Regina, A Coluccia, A Brancale, F Piscitelli, V Gatti, G Maga, ... Journal of medicinal chemistry 54 (6), 1587-1598, 2011 | 209* | 2011 |
| Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide R Ragno, A Coluccia, G La Regina, G De Martino, F Piscitelli, ... Journal of medicinal chemistry 49 (11), 3172-3184, 2006 | 206 | 2006 |
| New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity G La Regina, R Silvestri, M Artico, A Lavecchia, E Novellino, O Befani, ... Journal of medicinal chemistry 50 (5), 922-931, 2007 | 138 | 2007 |
| Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors G La Regina, R Bai, WM Rensen, E Di Cesare, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 56 (1), 123-149, 2013 | 135 | 2013 |
| New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies G La Regina, T Sarkar, R Bai, MC Edler, R Saletti, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 52 (23), 7512-7527, 2009 | 115 | 2009 |
| Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2 … R Ragno, M Artico, G De Martino, G La Regina, A Coluccia, A Di Pasquali, ... Journal of medicinal chemistry 48 (1), 213-223, 2005 | 97 | 2005 |
| Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability G La Regina, R Bai, W Rensen, A Coluccia, F Piscitelli, V Gatti, ... Journal of medicinal chemistry 54 (24), 8394-8406, 2011 | 94 | 2011 |
| New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer G La Regina, R Bai, A Coluccia, V Famiglini, S Pelliccia, S Passacantilli, ... Journal of medicinal chemistry 57 (15), 6531-6552, 2014 | 91 | 2014 |
| Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides R Silvestri, MG Cascio, G La Regina, F Piscitelli, A Lavecchia, A Brizzi, ... Journal of medicinal chemistry 51 (6), 1560-1576, 2008 | 89 | 2008 |
| Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors GL Regina, A Coluccia, R Silvestri Antiviral Chemistry and Chemotherapy 20 (6), 213-237, 2010 | 81 | 2010 |
| Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): A New Class of Agents with High Apoptotic Activity in Chronic Myelogenous Leukemia K562 Cells and in Cells … R Silvestri, G Marfe, M Artico, G La Regina, A Lavecchia, E Novellino, ... Journal of medicinal chemistry 49 (19), 5840-5844, 2006 | 77 | 2006 |
| Imidazole analogues of fluoxetine, a novel class of anti-Candida agents R Silvestri, M Artico, G La Regina, A Di Pasquali, G De Martino, ... Journal of medicinal chemistry 47 (16), 3924-3926, 2004 | 75 | 2004 |
| Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid CB1 Receptor F Piscitelli, A Ligresti, G La Regina, A Coluccia, L Morera, M Allarà, ... Journal of medicinal chemistry 55 (11), 5627-5631, 2012 | 74 | 2012 |
| Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both … L Masuelli, F Pantanella, G La Regina, M Benvenuto, M Fantini, R Mattera, ... Tumor Biology 37, 3705-3717, 2016 | 72 | 2016 |
| Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse … F Piscitelli, A Coluccia, A Brancale, G La Regina, A Sansone, C Giordano, ... Journal of medicinal chemistry 52 (7), 1922-1934, 2009 | 68 | 2009 |
| Novel 1-[2-(Diarylmethoxy) ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure− activity relationship investigation G De Martino, G La Regina, A Di Pasquali, R Ragno, A Bergamini, ... Journal of medicinal chemistry 48 (13), 4378-4388, 2005 | 68 | 2005 |
