Genetic influences on osteoarthritis in women: a twin study TD Spector, F Cicuttini, J Baker, J Loughlin, D Hart Bmj 312 (7036), 940-943, 1996 | 1038 | 1996 |
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency RE Dickinson, H Griffin, V Bigley, LN Reynard, R Hussain, M Haniffa, ... Blood, The Journal of the American Society of Hematology 118 (10), 2656-2658, 2011 | 498 | 2011 |
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females J Loughlin, B Dowling, K Chapman, L Marcelline, Z Mustafa, L Southam, ... Proceedings of the National Academy of Sciences 101 (26), 9757-9762, 2004 | 479 | 2004 |
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study arcOGEN Consortium, arcOGEN Collaborators The Lancet 380 (9844), 815-823, 2012 | 450 | 2012 |
A genome‐wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22 HJM Kerkhof, RJ Lories, I Meulenbelt, I Jonsdottir, AM Valdes, P Arp, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 280 | 2010 |
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee AM Valdes, J Loughlin, MV Oene, K Chapman, GL Surdulescu, M Doherty, ... Arthritis & Rheumatism 56 (1), 137-146, 2007 | 275 | 2007 |
Mutations in fibroblast growth-factor receptor 3 in sporadic cases of achondroplasia occur exclusively on the paternally derived chromosome DJ Wilkin, JK Szabo, R Cameron, S Henderson, GA Bellus, ML Mack, ... The American Journal of Human Genetics 63 (3), 711-716, 1998 | 275 | 1998 |
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis I Meulenbelt, JL Min, S Bos, N Riyazi, JJ Houwing-Duistermaat, ... Human molecular genetics 17 (12), 1867-1875, 2008 | 259 | 2008 |
Large‐scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand E Evangelou, K Chapman, I Meulenbelt, FB Karassa, J Loughlin, A Carr, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 237 | 2009 |
An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage L Southam, J Rodriguez-Lopez, JM Wilkins, M Pombo-Suarez, S Snelling, ... Human molecular genetics 16 (18), 2226-2232, 2007 | 235 | 2007 |
Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women AM Valdes, M Van Oene, DJ Hart, GL Surdulescu, J Loughlin, M Doherty, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 225 | 2006 |
Mutations in the region encoding the von Willebrand factor A domain of matrilin-3 are associated with multiple epiphyseal dysplasia KL Chapman, GR Mortier, K Chapman, J Loughlin, ME Grant, MD Briggs Nature genetics 28 (4), 393-396, 2001 | 224 | 2001 |
The genetic epidemiology of human primary osteoarthritis: current status J Loughlin Expert reviews in molecular medicine 7 (9), 1-12, 2005 | 223 | 2005 |
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility K Chapman, A Takahashi, I Meulenbelt, C Watson, J Rodriguez-Lopez, ... Human molecular genetics 17 (10), 1497-1504, 2008 | 221 | 2008 |
Estrogen receptor α gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women AP Bergink, JB van Meurs, J Loughlin, PP Arp, Y Fang, A Hofman, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 209 | 2003 |
Characterization of the cartilage DNA methylome in knee and hip osteoarthritis MD Rushton, LN Reynard, MJ Barter, R Refaie, KS Rankin, DA Young, ... Arthritis & rheumatology 66 (9), 2450-2460, 2014 | 199 | 2014 |
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 E Evangelou, AM Valdes, HJM Kerkhof, U Styrkarsdottir, YY Zhu, ... Annals of the rheumatic diseases 70 (2), 349-355, 2011 | 195 | 2011 |
Recent advances in the genetic investigation of osteoarthritis CA Peach, AJ Carr, J Loughlin Trends in molecular medicine 11 (4), 186-191, 2005 | 186 | 2005 |
Genetic epidemiology of primary osteoarthritis J Loughlin Current opinion in rheumatology 13 (2), 111-116, 2001 | 185 | 2001 |
A variant in MCF2L is associated with osteoarthritis AG Day-Williams, L Southam, K Panoutsopoulou, NW Rayner, T Esko, ... The American Journal of Human Genetics 89 (3), 446-450, 2011 | 180 | 2011 |