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John Loughlin
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Genetic influences on osteoarthritis in women: a twin study
TD Spector, F Cicuttini, J Baker, J Loughlin, D Hart
Bmj 312 (7036), 940-943, 1996
10381996
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
RE Dickinson, H Griffin, V Bigley, LN Reynard, R Hussain, M Haniffa, ...
Blood, The Journal of the American Society of Hematology 118 (10), 2656-2658, 2011
4982011
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females
J Loughlin, B Dowling, K Chapman, L Marcelline, Z Mustafa, L Southam, ...
Proceedings of the National Academy of Sciences 101 (26), 9757-9762, 2004
4792004
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
arcOGEN Consortium, arcOGEN Collaborators
The Lancet 380 (9844), 815-823, 2012
4502012
A genome‐wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
HJM Kerkhof, RJ Lories, I Meulenbelt, I Jonsdottir, AM Valdes, P Arp, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2010
2802010
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee
AM Valdes, J Loughlin, MV Oene, K Chapman, GL Surdulescu, M Doherty, ...
Arthritis & Rheumatism 56 (1), 137-146, 2007
2752007
Mutations in fibroblast growth-factor receptor 3 in sporadic cases of achondroplasia occur exclusively on the paternally derived chromosome
DJ Wilkin, JK Szabo, R Cameron, S Henderson, GA Bellus, ML Mack, ...
The American Journal of Human Genetics 63 (3), 711-716, 1998
2751998
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis
I Meulenbelt, JL Min, S Bos, N Riyazi, JJ Houwing-Duistermaat, ...
Human molecular genetics 17 (12), 1867-1875, 2008
2592008
Large‐scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
E Evangelou, K Chapman, I Meulenbelt, FB Karassa, J Loughlin, A Carr, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2009
2372009
An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage
L Southam, J Rodriguez-Lopez, JM Wilkins, M Pombo-Suarez, S Snelling, ...
Human molecular genetics 16 (18), 2226-2232, 2007
2352007
Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women
AM Valdes, M Van Oene, DJ Hart, GL Surdulescu, J Loughlin, M Doherty, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2006
2252006
Mutations in the region encoding the von Willebrand factor A domain of matrilin-3 are associated with multiple epiphyseal dysplasia
KL Chapman, GR Mortier, K Chapman, J Loughlin, ME Grant, MD Briggs
Nature genetics 28 (4), 393-396, 2001
2242001
The genetic epidemiology of human primary osteoarthritis: current status
J Loughlin
Expert reviews in molecular medicine 7 (9), 1-12, 2005
2232005
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility
K Chapman, A Takahashi, I Meulenbelt, C Watson, J Rodriguez-Lopez, ...
Human molecular genetics 17 (10), 1497-1504, 2008
2212008
Estrogen receptor α gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women
AP Bergink, JB van Meurs, J Loughlin, PP Arp, Y Fang, A Hofman, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2003
2092003
Characterization of the cartilage DNA methylome in knee and hip osteoarthritis
MD Rushton, LN Reynard, MJ Barter, R Refaie, KS Rankin, DA Young, ...
Arthritis & rheumatology 66 (9), 2450-2460, 2014
1992014
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
E Evangelou, AM Valdes, HJM Kerkhof, U Styrkarsdottir, YY Zhu, ...
Annals of the rheumatic diseases 70 (2), 349-355, 2011
1952011
Recent advances in the genetic investigation of osteoarthritis
CA Peach, AJ Carr, J Loughlin
Trends in molecular medicine 11 (4), 186-191, 2005
1862005
Genetic epidemiology of primary osteoarthritis
J Loughlin
Current opinion in rheumatology 13 (2), 111-116, 2001
1852001
A variant in MCF2L is associated with osteoarthritis
AG Day-Williams, L Southam, K Panoutsopoulou, NW Rayner, T Esko, ...
The American Journal of Human Genetics 89 (3), 446-450, 2011
1802011
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