Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process I Iacovache, S De Carlo, N Cirauqui, M Dal Peraro, FG Van Der Goot, ... Nature communications 7 (1), 12062, 2016 | 175 | 2016 |
Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores C Cao, N Cirauqui, MJ Marcaida, E Buglakova, A Duperrex, A Radenovic, ... Nature communications 10 (1), 4918, 2019 | 92 | 2019 |
Mapping the sensing spots of aerolysin for single oligonucleotides analysis C Cao, MY Li, N Cirauqui, YQ Wang, M Dal Peraro, H Tian, YT Long Nature communications 9 (1), 2823, 2018 | 74 | 2018 |
Melanin-concentrating hormone receptor 1 antagonists: a new perspective for the pharmacologic treatment of obesity G Rivera, V Bocanegra-García, S Galiano, N Cirauqui, J Ceras, S Pérez, ... Current medicinal chemistry 15 (10), 1025-1043, 2008 | 65 | 2008 |
Aerolysin nanopores decode digital information stored in tailored macromolecular analytes C Cao, LF Krapp, A Al Ouahabi, NF König, N Cirauqui, A Radenovic, ... Science Advances 6 (50), eabc2661, 2020 | 61 | 2020 |
Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family N Cirauqui, LA Abriata, FG Van Der Goot, M Dal Peraro Scientific reports 7 (1), 13932, 2017 | 53 | 2017 |
Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi R Martin-Escolano, E Moreno-Viguri, M Santivanez-Veliz, ... Journal of medicinal chemistry 61 (13), 5643-5663, 2018 | 38 | 2018 |
In Vitro and in Vivo Anti-Trypanosoma cruzi Activity of New Arylamine Mannich Base-Type Derivatives E Moreno-Viguri, C Jimenez-Montes, R Martin-Escolano, ... Journal of Medicinal Chemistry 59 (24), 10929-10945, 2016 | 33 | 2016 |
BK polyomavirus genotypes Ia and Ib1 exhibit different biological properties in renal transplant recipients RB Varella, ACJ Zalona, NC Diaz, MG Zalis, G Santoro-Lopes Virus research 243, 65-68, 2018 | 21 | 2018 |
Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation R Paucar, R Martin-Escolano, E Moreno-Viguri, A Azqueta, N Cirauqui, ... Bioorganic & Medicinal Chemistry 27 (17), 3902-3917, 2019 | 20 | 2019 |
Novel sulfonylurea derivatives as H3 receptor antagonists. Preliminary SAR studies J Ceras, N Cirauqui, S Pérez-Silanes, I Aldana, A Monge, S Galiano European journal of medicinal chemistry 52, 1-13, 2012 | 20 | 2012 |
Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity S Galiano, J Ceras, N Cirauqui, S Pérez, L Juanenea, G Rivera, I Aldana, ... Bioorganic & medicinal chemistry 15 (11), 3896-3911, 2007 | 17 | 2007 |
Phase separation and disorder-to-order transition of human brain expressed X-linked 3 (hBEX3) in the presence of small fragments of tRNA MJ do Amaral, TS Araujo, NC Díaz, F Accornero, CR Polycarpo, ... Journal of molecular biology 432 (7), 2319-2348, 2020 | 16 | 2020 |
Analysis of worldwide sequence mutations in Zika virus proteins E, NS1, NS3 and NS5 from a structural point of view CF Baez, VA Barel, AMT De Souza, CR Rodrigues, RB Varella, ... Molecular BioSystems 13 (1), 122-131, 2017 | 13 | 2017 |
Building a MCHR1 homology model provides insight into the receptor–antagonist contacts that are important for the development of new anti-obesity agents N Cirauqui, AK Schrey, S Galiano, J Ceras, S Pérez-Silanes, I Aldana, ... Bioorganic & medicinal chemistry 18 (21), 7365-7379, 2010 | 13 | 2010 |
Phylogenetic and structural analysis of merkel cell polyomavirus VP1 in Brazilian samples CF Baez, NC Diaz, MT Venceslau, FB Luz, MAAM Guimarães, MG Zalis, ... Virus research 221, 1-7, 2016 | 12 | 2016 |
A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives R Paucar, R Martín-Escolano, E Moreno-Viguri, N Cirauqui, ... European Journal of Medicinal Chemistry 163, 569-582, 2019 | 10 | 2019 |
Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial … R Martín-Escolano, J Martín-Escolano, R Ballesteros-Garrido, N Cirauqui, ... Parasitology Research 119, 2943-2954, 2020 | 8 | 2020 |
In vivo biological evaluation of a synthetic royleanone derivative as a promising fast-acting trypanocidal agent by inducing mitochondrial-dependent necrosis R Martin-Escolano, JJ Guardia, J Martín-Escolano, N Cirauqui, ... Journal of Natural Products 83 (12), 3571-3583, 2020 | 7 | 2020 |
Molecular modeling study of a series of amodiaquine analogues with antimalarial activity ACC de Sousa, NC Diaz, AMT de Souza, LM Cabral, HC Castro, ... Medicinal Chemistry Research 24, 3529-3536, 2015 | 7 | 2015 |