Lymph protects metastasizing melanoma cells from ferroptosis JM Ubellacker, A Tasdogan, V Ramesh, B Shen, EC Mitchell, ... Nature 585 (7823), 113-118, 2020 | 601 | 2020 |
Metabolic heterogeneity confers differences in melanoma metastatic potential A Tasdogan, B Faubert, V Ramesh, JM Ubellacker, BO Shen, ... Nature 577 (7788), 115-120, 2020 | 378 | 2020 |
Biomarkers of NAFLD progression: A lipidomics approach to an epidemic1 [S] DL Gorden, DS Myers, PT Ivanova, E Fahy, MR Maurya, S Gupta, J Min, ... Journal of lipid research 56 (3), 722-736, 2015 | 345 | 2015 |
Drugs for allosteric sites on receptors CJ Wenthur, PR Gentry, TP Mathews, CW Lindsley Annual review of pharmacology and toxicology 54 (1), 165-184, 2014 | 267 | 2014 |
Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study A Shrivastava, A Kumar, JD Thomas, KF Laserson, G Bhushan, MD Carter, ... The Lancet Global Health 5 (4), e458-e466, 2017 | 114 | 2017 |
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells AJ Kennedy, TP Mathews, Y Kharel, SD Field, ML Moyer, JE East, ... Journal of medicinal chemistry 54 (10), 3524-3548, 2011 | 97 | 2011 |
Sum of the parts: mass spectrometry-based metabolomics SB Milne, TP Mathews, DS Myers, PT Ivanova, HA Brown Biochemistry 52 (22), 3829-3840, 2013 | 84 | 2013 |
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate Y Kharel, TP Mathews, AM Gellett, JL Tomsig, PC Kennedy, ML Moyer, ... Biochemical Journal 440 (3), 345-353, 2011 | 78 | 2011 |
Discovery, biological evaluation, and structure− activity relationship of amidine based sphingosine kinase inhibitors TP Mathews, AJ Kennedy, Y Kharel, PC Kennedy, O Nicoara, M Sunkara, ... Journal of medicinal chemistry 53 (7), 2766-2778, 2010 | 75 | 2010 |
Compartmentalized metabolism supports midgestation mammalian development A Solmonson, B Faubert, W Gu, A Rao, MA Cowdin, I Menendez-Montes, ... Nature 604 (7905), 349-353, 2022 | 69 | 2022 |
Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues AW DeVilbiss, Z Zhao, MS Martin-Sandoval, JM Ubellacker, A Tasdogan, ... Elife 10, e61980, 2021 | 65 | 2021 |
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ... Cancer cell 40 (9), 939-956. e16, 2022 | 62 | 2022 |
Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ... Nature communications 10 (1), 5604, 2019 | 55 | 2019 |
TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling SY Kasitinon, U Eskiocak, M Martin, D Bezwada, V Khivansara, ... Cell reports 28 (9), 2293-2305. e9, 2019 | 53 | 2019 |
Stable isotope tracing to assess tumor metabolism in vivo B Faubert, A Tasdogan, SJ Morrison, TP Mathews, RJ DeBerardinis Nature protocols 16 (11), 5123-5145, 2021 | 52 | 2021 |
Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs FW Foss Jr, TP Mathews, Y Kharel, PC Kennedy, AH Snyder, MD Davis, ... Bioorganic & medicinal chemistry 17 (16), 6123-6136, 2009 | 47 | 2009 |
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ... Proceedings of the National Academy of Sciences 119 (6), e2120617119, 2022 | 46 | 2022 |
A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution X Grau-Bové, C Navarrete, C Chiva, T Pribasnig, M Antó, G Torruella, ... Nature ecology & evolution 6 (7), 1007-1023, 2022 | 45 | 2022 |
Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration L Qi, MS Martin-Sandoval, S Merchant, W Gu, M Eckhardt, TP Mathews, ... Cell Stem Cell 28 (11), 1982-1999. e8, 2021 | 45 | 2021 |
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage S Jun, S Mahesula, TP Mathews, MS Martin-Sandoval, Z Zhao, ... Cell metabolism 33 (9), 1777-1792. e8, 2021 | 42 | 2021 |