关注
Thomas P. Mathews
Thomas P. Mathews
Assistant Professor, UT Southwestern Medical center
在 utsouthwestern.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Lymph protects metastasizing melanoma cells from ferroptosis
JM Ubellacker, A Tasdogan, V Ramesh, B Shen, EC Mitchell, ...
Nature 585 (7823), 113-118, 2020
6012020
Metabolic heterogeneity confers differences in melanoma metastatic potential
A Tasdogan, B Faubert, V Ramesh, JM Ubellacker, BO Shen, ...
Nature 577 (7788), 115-120, 2020
3782020
Biomarkers of NAFLD progression: A lipidomics approach to an epidemic1 [S]
DL Gorden, DS Myers, PT Ivanova, E Fahy, MR Maurya, S Gupta, J Min, ...
Journal of lipid research 56 (3), 722-736, 2015
3452015
Drugs for allosteric sites on receptors
CJ Wenthur, PR Gentry, TP Mathews, CW Lindsley
Annual review of pharmacology and toxicology 54 (1), 165-184, 2014
2672014
Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study
A Shrivastava, A Kumar, JD Thomas, KF Laserson, G Bhushan, MD Carter, ...
The Lancet Global Health 5 (4), e458-e466, 2017
1142017
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells
AJ Kennedy, TP Mathews, Y Kharel, SD Field, ML Moyer, JE East, ...
Journal of medicinal chemistry 54 (10), 3524-3548, 2011
972011
Sum of the parts: mass spectrometry-based metabolomics
SB Milne, TP Mathews, DS Myers, PT Ivanova, HA Brown
Biochemistry 52 (22), 3829-3840, 2013
842013
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate
Y Kharel, TP Mathews, AM Gellett, JL Tomsig, PC Kennedy, ML Moyer, ...
Biochemical Journal 440 (3), 345-353, 2011
782011
Discovery, biological evaluation, and structure− activity relationship of amidine based sphingosine kinase inhibitors
TP Mathews, AJ Kennedy, Y Kharel, PC Kennedy, O Nicoara, M Sunkara, ...
Journal of medicinal chemistry 53 (7), 2766-2778, 2010
752010
Compartmentalized metabolism supports midgestation mammalian development
A Solmonson, B Faubert, W Gu, A Rao, MA Cowdin, I Menendez-Montes, ...
Nature 604 (7905), 349-353, 2022
692022
Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
AW DeVilbiss, Z Zhao, MS Martin-Sandoval, JM Ubellacker, A Tasdogan, ...
Elife 10, e61980, 2021
652021
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ...
Cancer cell 40 (9), 939-956. e16, 2022
622022
Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer
A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ...
Nature communications 10 (1), 5604, 2019
552019
TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling
SY Kasitinon, U Eskiocak, M Martin, D Bezwada, V Khivansara, ...
Cell reports 28 (9), 2293-2305. e9, 2019
532019
Stable isotope tracing to assess tumor metabolism in vivo
B Faubert, A Tasdogan, SJ Morrison, TP Mathews, RJ DeBerardinis
Nature protocols 16 (11), 5123-5145, 2021
522021
Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs
FW Foss Jr, TP Mathews, Y Kharel, PC Kennedy, AH Snyder, MD Davis, ...
Bioorganic & medicinal chemistry 17 (16), 6123-6136, 2009
472009
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ...
Proceedings of the National Academy of Sciences 119 (6), e2120617119, 2022
462022
A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution
X Grau-Bové, C Navarrete, C Chiva, T Pribasnig, M Antó, G Torruella, ...
Nature ecology & evolution 6 (7), 1007-1023, 2022
452022
Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration
L Qi, MS Martin-Sandoval, S Merchant, W Gu, M Eckhardt, TP Mathews, ...
Cell Stem Cell 28 (11), 1982-1999. e8, 2021
452021
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage
S Jun, S Mahesula, TP Mathews, MS Martin-Sandoval, Z Zhao, ...
Cell metabolism 33 (9), 1777-1792. e8, 2021
422021
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