Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project MB Gerstein, ZJ Lu, EL Van Nostrand, C Cheng, BI Arshinoff, T Liu, ... Science 330 (6012), 1775-1787, 2010 | 1146 | 2010 |
Broad chromosomal domains of histone modification patterns in C. elegans T Liu, A Rechtsteiner, TA Egelhofer, A Vielle, I Latorre, MS Cheung, ... Genome research 21 (2), 227-236, 2011 | 316 | 2011 |
The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny A Rechtsteiner, S Ercan, T Takasaki, TM Phippen, TA Egelhofer, W Wang, ... PLoS genetics 6 (9), e1001091, 2010 | 213 | 2010 |
ERK: a double-edged sword in cancer. ERK-dependent apoptosis as a potential therapeutic strategy for cancer R Sugiura, R Satoh, T Takasaki Cells 10 (10), 2509, 2021 | 212 | 2021 |
Trans-generational epigenetic regulation of C. elegans primordial germ cells H Furuhashi, T Takasaki, A Rechtsteiner, T Li, H Kimura, PM Checchi, ... Epigenetics & chromatin 3, 1-21, 2010 | 134 | 2010 |
MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in Caenorhabditis elegans T Takasaki, Z Liu, Y Habara, K Nishiwaki, J Nakayama, K Inoue, ... Oxford University Press for The Company of Biologists Limited 134 (4), 757-767, 2007 | 61 | 2007 |
MRG-1, a mortality factor-related chromodomain protein, is required maternally for primordial germ cells to initiate mitotic proliferation in C. elegans M Fujita, T Takasaki, N Nakajima, T Kawano, Y Shimura, H Sakamoto Mechanisms of development 114 (1-2), 61-69, 2002 | 47 | 2002 |
Distinct Roles of Two Histone Methyltransferases in Transmitting H3K36me3-Based Epigenetic Memory Across Generations in Caenorhabditis elegans J Kreher, T Takasaki, C Cockrum, S Sidoli, BA Garcia, ON Jensen, ... Genetics 210 (3), 969-982, 2018 | 43 | 2018 |
More than just an immunosuppressant: the emerging role of FTY720 as a novel inducer of ROS and apoptosis T Takasaki, K Hagihara, R Satoh, R Sugiura Oxidative medicine and cellular longevity 2018 (1), 4397159, 2018 | 38 | 2018 |
Sequestration of the PKC ortholog Pck2 in stress granules as a feedback mechanism of MAPK signaling in fission yeast Y Kanda, R Satoh, T Takasaki, N Tomimoto, K Tsuchiya, CA Tsai, ... Journal of Cell Science 134 (2), jcs250191, 2021 | 16 | 2021 |
Down‐regulation of dual‐specificity phosphatase 6, a negative regulator of oncogenic ERK signaling, by ACA‐28 induces apoptosis in NIH/3T3 cells overexpressing HER2/ErbB2 Y Kanda, A Mizuno, T Takasaki, R Satoh, K Hagihara, T Masuko, Y Endo, ... Genes to Cells 26 (2), 109-116, 2021 | 11 | 2021 |
Discovery of new benzhydrol biscarbonate esters as potent and selective apoptosis inducers of human melanomas bearing the activated ERK pathway: SAR studies on an ERK MAPK … R Satoh, N Hamada, A Yamada, Y Kanda, F Ishikawa, T Takasaki, ... Bioorganic Chemistry 103, 104137, 2020 | 9 | 2020 |
ACAGT-007a, an ERK MAPK signaling modulator, in combination with AKT signaling inhibition induces apoptosis in kras mutant pancreatic cancer T3M4 and MIA-Pa-Ca-2 cells GI Khandakar, R Satoh, T Takasaki, K Fujitani, G Tanabe, K Sakai, ... Cells 11 (4), 702, 2022 | 8 | 2022 |
A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis K Hagihara, K Kinoshita, K Ishida, S Hojo, Y Kameoka, R Satoh, ... Microbial Cell 4 (12), 390, 2017 | 7 | 2017 |
Distinct modes of stress granule assembly mediated by the KH‐type RNA‐binding protein Rnc1 R Satoh, N Hara, A Kawasaki, T Takasaki, R Sugiura Genes to Cells 23 (9), 778-785, 2018 | 6 | 2018 |
Distinct spatiotemporal distribution of Hsp90 under high-heat and mild-heat stress conditions in fission yeast T Takasaki, N Tomimoto, T Ikehata, R Satoh, R Sugiura microPublication Biology 2021, 2021 | 4 | 2021 |
Stress granules as a feedback mechanism of MAPK signaling by sequestering PKC/Pck2 Y Kanda, R Satoh, T Takasaki, N Tomimoto, K Tsuchiya, CA Tsai, ... Journal of Cell Science 134, jcs250191, 2020 | 4 | 2020 |
Restricted distribution of mrg‐1 mRNA in C. elegans primordial germ cells through germ granule‐independent regulation T Miwa, T Takasaki, K Inoue, H Sakamoto Genes to Cells 20 (11), 932-942, 2015 | 3 | 2015 |
Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast T Takasaki, R Utsumi, E Shimada, A Bamba, K Hagihara, R Satoh, ... Microbial Cell 10 (6), 133, 2023 | 2 | 2023 |
Arsenite treatment induces Hsp90 aggregatesdistinct from conventional stress granules in fission yeast N Tomimoto, T Takasaki, R Sugiura Microbial Cell 11, 242, 2024 | 1 | 2024 |