Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang Science 360 (6387), 439-444, 2018 | 2055 | 2018 |
RNA targeting with CRISPR–Cas13 OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ... Nature 550 (7675), 280-284, 2017 | 1863 | 2017 |
RNA editing with CRISPR-Cas13 DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ... Science 358 (6366), 1019-1027, 2017 | 1779 | 2017 |
Field-deployable viral diagnostics using CRISPR-Cas13 C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ... Science 360 (6387), 444-448, 2018 | 1172 | 2018 |
SHERLOCK: nucleic acid detection with CRISPR nucleases MJ Kellner, JG Koob, JS Gootenberg, OO Abudayyeh, F Zhang Nature protocols 14 (10), 2986-3012, 2019 | 1077 | 2019 |
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, ... Cell stem cell 27 (6), 951-961. e5, 2020 | 488 | 2020 |
A cytosine deaminase for programmable single-base RNA editing OO Abudayyeh, JS Gootenberg, B Franklin, J Koob, MJ Kellner, A Ladha, ... Science 365 (6451), 382-386, 2019 | 405 | 2019 |
High-resolution structure of Cas13b and biochemical characterization of RNA targeting and cleavage IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ... Cell reports 26 (13), 3741-3751. e5, 2019 | 108 | 2019 |
Nucleic acid detection of plant genes using CRISPR-Cas13 OO Abudayyeh, JS Gootenberg, MJ Kellner, F Zhang The CRISPR journal 2 (3), 165-171, 2019 | 105 | 2019 |
A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing MJ Kellner, JJ Ross, J Schnabl, MPS Dekens, M Matl, R Heinen, ... Frontiers in Molecular Biosciences 9, 801309, 2022 | 64 | 2022 |
Identification of lectin receptors for conserved SARS‐CoV‐2 glycosylation sites D Hoffmann, S Mereiter, Y Jin Oh, V Monteil, E Elder, R Zhu, D Canena, ... The EMBO Journal 40 (19), e108375, 2021 | 64 | 2021 |
NanoPARE: parallel analysis of RNA 5′ ends from low-input RNA MA Schon, MJ Kellner, A Plotnikova, F Hofmann, MD Nodine Genome research 28 (12), 1931-1942, 2018 | 63 | 2018 |
Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic GY Oudit, K Wang, A Viveiros, MJ Kellner, JM Penninger Cell 186 (5), 906-922, 2023 | 62 | 2023 |
MicroRNA dynamics and functions during Arabidopsis embryogenesis A Plotnikova, MJ Kellner, MA Schon, M Mosiolek, MD Nodine The Plant Cell 31 (12), 2929-2946, 2019 | 55 | 2019 |
Clinical grade ACE2 as a universal agent to block SARS‐CoV‐2 variants V Monteil, B Eaton, E Postnikova, M Murphy, B Braunsfeld, I Crozier, ... EMBO Molecular Medicine 14 (8), e15230, 2022 | 36 | 2022 |
Crispr effector system based amplification methods, systems, and diagnostics F Zhang, M Kellner, J Gootenberg, O Abudayyeh US Patent App. 16/973,061, 2021 | 13 | 2021 |
Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics MJ Kellner, M Matl, JJ Ross, J Schnabl, D Handler, R Heinen, J Schaeffer, ... MedRxiv, 2021.01. 19.21250079, 2021 | 10 | 2021 |
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections V Monteil, H Kwon, L John, C Salata, G Jonsson, SU Vorrink, S Appelberg, ... Nature Communications 14 (1), 6785, 2023 | 4 | 2023 |
Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells VM Monteil, SC Wright, M Dyczynski, MJ Kellner, S Appelberg, SW Platzer, ... Nature Microbiology 9 (6), 1499-1512, 2024 | 2 | 2024 |
Crispr/cas and transposase based amplification compositions, systems and methods F Zhang, M Kellner, J Gootenberg, O Abudayyeh US Patent App. 17/054,428, 2021 | 1 | 2021 |