Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases M Tiemi Shio, SC Eisenbarth, M Savaria, AF Vinet, MJ Bellemare, ... PLoS pathogens 5 (8), e1000559, 2009 | 412 | 2009 |
Leishmania virulence factors: focus on the metalloprotease GP63 M Olivier, VD Atayde, A Isnard, K Hassani, MT Shio Microbes and infection 14 (15), 1377-1389, 2012 | 270 | 2012 |
Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection M Jaramillo, MA Gomez, O Larsson, MT Shio, I Topisirovic, I Contreras, ... Cell host & microbe 9 (4), 331-341, 2011 | 209 | 2011 |
Impact of Leishmania metalloprotease GP63 on macrophage signaling A Isnard, MT Shio, M Olivier Frontiers in cellular and infection microbiology 2, 72, 2012 | 194 | 2012 |
Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63 I Contreras, MA Gómez, O Nguyen, MT Shio, RW McMaster, M Olivier PLoS pathogens 6 (10), e1001148, 2010 | 177 | 2010 |
Malarial pigment hemozoin and the innate inflammatory response M Olivier, K Van Den Ham, MT Shio, FA Kassa, S Fougeray Frontiers in immunology 5, 74452, 2014 | 174 | 2014 |
Leishmania evades host immunity by inhibiting antigen cross-presentation through direct cleavage of the SNARE VAMP8 D Matheoud, N Moradin, A Bellemare-Pelletier, MT Shio, WJ Hong, ... Cell host & microbe 14 (1), 15-25, 2013 | 158 | 2013 |
Host Cell Signalling and Leishmania Mechanisms of Evasion MT Shio, K Hassani, A Isnard, B Ralph, I Contreras, MA Gomez, ... Journal of tropical medicine 2012 (1), 819512, 2012 | 144 | 2012 |
Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes K Hassani, MT Shio, C Martel, D Faubert, M Olivier PloS one 9 (4), e95007, 2014 | 137 | 2014 |
Inflammation-Driven Reprogramming of CD4+Foxp3+ Regulatory T Cells into Pathogenic Th1/Th17 T Effectors Is Abrogated by mTOR Inhibition in vivo E Yurchenko, MT Shio, TC Huang, M Da Silva Martins, M Szyf, ... PloS one 7 (4), e35572, 2012 | 137 | 2012 |
Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif I Abu-Dayyeh, MT Shio, S Sato, S Akira, B Cousineau, M Olivier PLoS neglected tropical diseases 2 (12), e305, 2008 | 125 | 2008 |
Innate inflammatory response to the malarial pigment hemozoin MT Shio, FA Kassa, MJ Bellemare, M Olivier Microbes and infection 12 (12-13), 889-899, 2010 | 111 | 2010 |
Synthetic Plasmodium-like hemozoin activates the immune response: a morphology-function study M Jaramillo, MJ Bellemare, C Martel, MT Shio, AP Contreras, M Godbout, ... PloS one 4 (9), e6957, 2009 | 99 | 2009 |
PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection MT Shio, JG Christian, JY Jung, KP Chang, M Olivier PLoS neglected tropical diseases 9 (6), e0003868, 2015 | 89 | 2015 |
New inflammation-related biomarkers during malaria infection FA Kassa, MT Shio, MJ Bellemare, B Faye, M Ndao, M Olivier PloS one 6 (10), e26495, 2011 | 61 | 2011 |
Impact of Leishmania mexicana Infection on Dendritic Cell Signaling and Functions I Contreras, JA Estrada, H Guak, C Martel, A Borjian, B Ralph, MT Shio, ... PLoS Neglected Tropical Diseases 8 (9), e3202, 2014 | 53 | 2014 |
Drug delivery by tattooing to treat cutaneous leishmaniasis MT Shio, M Paquet, C Martel, T Bosschaerts, S Stienstra, M Olivier, ... Scientific reports 4 (1), 4156, 2014 | 36 | 2014 |
Leishmania survival mechanisms: the role of host phosphatases MT Shio, M Olivier Journal of leukocyte biology 88 (1), 1-3, 2010 | 34 | 2010 |
Immature macrophages derived from mouse bone marrow produce large amounts of IL-12p40 after LPS stimulation MAP Oliveira, G Lima, MT Shio, PJM Leenen, IA Abrahamsohn Journal of Leucocyte Biology 74 (5), 857-867, 2003 | 34 | 2003 |
The protein tyrosine phosphatase SHP-1 regulates phagolysosome biogenesis CP Gómez, M Tiemi Shio, P Duplay, M Olivier, A Descoteaux The Journal of Immunology 189 (5), 2203-2210, 2012 | 27 | 2012 |